Results 131 to 140 of about 384,078 (314)

Maximum walk entropy implies walk regularity [PDF]

open access: yesarXiv, 2014
The notion of walk entropy $S^V(G,\beta)$ for a graph $G$ at the inverse temperature $\beta$ was put forward recently by Estrada et al. (2014) \cite{6}. It was further proved by Benzi \cite{1} that a graph is walk-regular if and only if its walk entropy is maximum for all temperatures $\beta \in I$, where $I$ is a set of real numbers containing at ...
arxiv  

Advances in Nano‐Immunomodulatory Systems for the Treatment of Acute Kidney Injury

open access: yesAdvanced Science, EarlyView.
Based on the biodegradability and the immunological reactiveness, IMNs can be broadly classified into four categories. The first category includes types of biologically derived materials that cause immunomodulatory action and biodegradability like nanoparticles of cell membranes, extracellular vesicles, and exosomes.
Chenli Zhang   +5 more
wiley   +1 more source

BC‐11 is a covalent TMPRSS2 fragment inhibitor that impedes SARS‐CoV‐2 host cell entry

open access: yesArchiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
Drug repurposing has the potential to accelerate the discovery of TMPRSS2 inhibitors acting as COVID‐19 antivirals. In this regard, a low throughput screening led to the identification of BC‐11 as a covalent TMPRSS2 fragment inhibitor (IC50 = 1.44 µM), displaying significant SARS‐CoV‐2 entry inhibition (EC50 = 66 µM). Abstract Host cell entry of severe
Aurélien F. A. Moumbock   +3 more
wiley   +1 more source

Uncertainty principle for discrete Schrödinger evolution on graphs [PDF]

open access: yesarXiv, 2016
We consider the Schr\"odinger evolution on graph, i.e. solution to the equation $\partial_tu(t,\alpha)=i\sum_{\beta\in\mathcal{A}}L(\alpha,\beta)u(t,\beta)$, here $\mathcal{A}$ is the set of vertices of the graph and the matrix $(L(\alpha,\beta))_{\alpha,\beta\in\mathcal{A}}$ describes interaction between the vertices, in particular two vertices ...
arxiv  

X-ray and solution structures of human beta-2 glycoprotein I reveal a new mechanism of autoantibody recognition [PDF]

open access: green, 2020
Eliza A. Ruben   +11 more
openalex   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

open access: yesAdvanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu   +7 more
wiley   +1 more source

Osteosarcoma Cell‐Derived Migrasomes Promote Macrophage M2 Polarization to Aggravate Osteosarcoma Proliferation and Metastasis

open access: yesAdvanced Science, EarlyView.
Migrasomes are newly discovered organelles in migrating cells. This study finds that osteosarcoma cell‐derived migrasomes promote the tumor‐promoting phenotype of macrophages and further aggravate osteosarcoma malignant progression via milk fat globule‐EGF factor 8.
Wanshun Liu   +10 more
wiley   +1 more source

High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection

open access: yesAdvanced Science, EarlyView.
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni   +15 more
wiley   +1 more source

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