Results 231 to 240 of about 163,717 (335)

SUN-316 Binding of β-catenin to TCF1 and FoxO1 controls TGF-beta fibrogenic signalling pathways and predicts adverse outcomes in transplanted kidneys

, 2020
Ying Yang, Brian J. Nankivell, Padmashree Rao, Xiaojun Ren, Hong Yu, T. Chen, Qi Cao, Y. Wang, Yaming Wang, V.W. Lee, S. I. Alexander, Chow Heok P’ng, Natasha M. Rogers, Guoping Zheng, David C.H. Harris   +14 more
openalex   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

Erratum to aloe-emodin inhibits the proliferation, migration, and invasion of melanoma cells via inactivation of the Wnt/beta-catenin signaling pathway. [PDF]

Ann Transl Med
Editorial Office.
europepmc   +1 more source

A Rigorous Conceptual Framework for RegenX: A Nanomaterial-Enabled Therapeutic for Targeted Bone Regeneration via Integrated Wnt/$\beta$-Catenin and BMP/Smad Pathway Modulation

Shibah, Sami Rashid Mohammed
openalex   +1 more source

The Anticancer Poperties of Diosgenin on Colorectal Cancer Cells Induced by Wnt/Β Catenin Signaling Pathway [PDF]

Amir Abdolmaleki, Davood Rezazadeh, Mohsen Zhaleh, Houshang Nemati, Hamid Ghobadi, Fuzieh Khani-Hemmatabadi   +5 more
openalex   +1 more source

Nitrogen‐Boosted H2O2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration

Advanced Science, EarlyView.
PEA nanoenzymes are assembled from L‐arginine and EGCG. The nitrogen element in arginine enhances the thermodynamic feasibility of H2O2 production through PEA's oxygen reduction catalysis, enabling nitrogen‐dependent H2O2 release. Intradermal delivery of PEA via microneedles promotes efficient H2O2 synthesis, thereby stimulating regrowth in telogen ...
Yifei Wang, Yaojia Yang, Aoxue Wang, Chen Shen, Shenliang Tan, Changsheng Liu, Yuzheng Zhao, Xue Qu   +7 more
wiley   +1 more source

Faculty Opinions recommendation of Wnt/beta-catenin signaling has an essential role in the initiation of limb regeneration.

, 2007
Harukazu Nakamura
openalex   +2 more sources

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Simultaneous effect of naringenin and beta-catenin signaling inhibitor C-82 on modulating gene expression and functional pattern of mesenchymal stem cells from endometriosis patients. [PDF]

Iran J Basic Med Sci
Fazaeli H, Davoodi F, Sheikholeslami A, Sheykhhasan M, Kalhor N, Naserpour L, Jannatifar R, Sahraei SS.   +7 more
europepmc   +1 more source