Results 261 to 270 of about 143,797 (322)
NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES
Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti+4 more
wiley +1 more source
Tolypothrix Dichloromethane Ethylacetate fraction (TDEF) inhibits cisplatin resistance H357 cell through PI3K/AKT/beta-catenin pathway. [PDF]
Heisnam R+7 more
europepmc +1 more source
Abstract Background The emergence of multicellularity in animals marks a pivotal evolutionary event, which was likely enabled by molecular innovations in the way cells adhere and communicate with one another. β‐Catenin is significant to this transition due to its dual role as both a structural component in the cadherin–catenin complex and as a ...
Brian M. Walters+5 more
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Histopathological Study and Expression of Beta-Catenin in Congenital Choledochal Cyst in a Tertiary Care Pediatric Referral Center in South India. [PDF]
Philpose RT, Mohammed AA, Gowni AR.
europepmc +1 more source
Expression of Wnt5a and .BETA.-Catenin in Chinese Oral Squamous Cell Carcinoma of Tongue
En-xin Zhu+4 more
openalex +2 more sources
Beta-catenin (CTNNB1) plays a dual role in the cell, functioning both in cell adhesion and WNT signalling. In cell adhesion, CTNNB1 binds to cadherins in adherens junctions and anchors them to the cytoskeleton. This is crucial for reinforcing cell-cell junctions and maintaining structural integrity.
openaire +1 more source
Metabolic changes during cardiac regeneration in the axolotl
Abstract Background The axolotl is a prominent model organism of heart regeneration due to its ability to anatomically and functionally repair the heart after an injury that mimics human myocardial infarction. In humans, such an injury leads to permanent scarring. Cardiac regeneration has been linked to metabolism and the oxygenation state, but so far,
Anita Dittrich+10 more
wiley +1 more source