Results 261 to 270 of about 143,797 (322)

NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES

open access: yesChemMedChem, Accepted Article.
Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti   +4 more
wiley   +1 more source

Tolypothrix Dichloromethane Ethylacetate fraction (TDEF) inhibits cisplatin resistance H357 cell through PI3K/AKT/beta-catenin pathway. [PDF]

open access: yesAm J Cancer Res
Heisnam R   +7 more
europepmc   +1 more source

Absence of &beta;<i>-catenin</i> Mutations in Mouse Hepatoblastomas Induced by <i>N</i>, <i>N</i>-dimethylformamide

open access: bronze, 2004
Masakazu Kakuni   +6 more
openalex   +2 more sources

β‐Catenin localization in the ctenophore Mnemiopsis leidyi suggests an ancestral role in cell adhesion and nuclear function

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The emergence of multicellularity in animals marks a pivotal evolutionary event, which was likely enabled by molecular innovations in the way cells adhere and communicate with one another. β‐Catenin is significant to this transition due to its dual role as both a structural component in the cadherin–catenin complex and as a ...
Brian M. Walters   +5 more
wiley   +1 more source

Beta-catenin

open access: yes
Beta-catenin (CTNNB1) plays a dual role in the cell, functioning both in cell adhesion and WNT signalling. In cell adhesion, CTNNB1 binds to cadherins in adherens junctions and anchors them to the cytoskeleton. This is crucial for reinforcing cell-cell junctions and maintaining structural integrity.
openaire   +1 more source

Metabolic changes during cardiac regeneration in the axolotl

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The axolotl is a prominent model organism of heart regeneration due to its ability to anatomically and functionally repair the heart after an injury that mimics human myocardial infarction. In humans, such an injury leads to permanent scarring. Cardiac regeneration has been linked to metabolism and the oxygenation state, but so far,
Anita Dittrich   +10 more
wiley   +1 more source

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