Results 291 to 300 of about 143,797 (322)

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

SOX10, MITF, and microRNAs: Decoding their interplay in regulating melanoma plasticity

International Journal of Cancer, EarlyView.
Abstract Recent studies show that the dysregulation of the transcription factor SOX10 is essential for the development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcription factors at the post‐transcriptional level. The interactions between SOX10 and its targeting miRNAs form network motifs such as feedforward and
Xin Lai, Chunyan Luan, Zhesi Zhang, Anja Wessely, Markus V. Heppt, Carola Berking, Julio Vera   +6 more
wiley   +1 more source

Raab MS, Breitkreutz I, Tonon G, et al. Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling. Blood. 2009;113(7):1513-1521.

Blood
europepmc   +1 more source

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beta-catenin expression in pilomatrixomas. Relationship with beta-catenin gene mutations and comparison with beta-catenin expression in normal hair follicles

British Journal of Dermatology, 2001
beta-catenin functions in signal transduction in the Wnt signalling pathway, which has recently been implicated in hair follicle (HF) morphogenesis. beta-catenin gene mutations affecting exon 3 have been reported in a high percentage of human pilomatrixomas.
C Gamallo, J Palacios, Gema Moreno-Bueno, L Pérez-Gallego, F Contreras   +4 more
openaire   +3 more sources

Beta-catenin-activated hepatocellular adenoma in a male

Clinical Journal of Gastroenterology, 2021
Beta-catenin-activated hepatocellular adenoma is potentially malignant and warrants careful follow-up and surgical resection. Here, we report a 48-year-old man in whom a 55 mm single liver tumor was incidentally detected in the S1 segment. Contrast-enhanced computed tomography scans showed no enhancement in the early phase and a slight defection in the
Ryosuke Ishida, Yoshihiko Yano, Atsushi Yamamoto, Eiichiro Yasutomi, Yuri Hatazawa, Hiroki Hayashi, Yuuki Shiomi, Hidetoshi Gon, Satoshi Omiya, Maki Kanzawa, Tomoo Itoh, Yoshihide Ueda, Yuzo Kodama   +12 more
openaire   +3 more sources

The WNT/Beta-catenin pathway in melanoma

Frontiers in Bioscience, 2006
The Wnt/beta-catenin pathway is involved in various cellular activities--including determination, proliferation, migration and differentiation--in embryonic development and adult homeostasis. The deregulation or constitutive activation of the Wnt/beta-catenin pathway may lead to cancer formation.
Véronique Delmas, Lionel Larue
openaire   +3 more sources

Wnt/beta-Catenin Signaling in Glioma

Journal of Neuroimmune Pharmacology, 2012
Extensive data have shown that Wnt/beta-catenin signaling is associated with various disease pathologies, including an important role in tumorigenesis. Here, we review the regulation of Wnt/beta-catenin signaling in glioma, with particular focus on the expression signatures of the main components in Wnt/beta-catenin signaling, the role of key factors ...
Kailiang Zhang, Peiyu Pu, Lei Han, Junxia Zhang, Chunsheng Kang   +4 more
openaire   +3 more sources