Results 101 to 110 of about 3,421,347 (332)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Effect of Disturbance Regime on Alpha and Beta Diversity of Rock Pools

Diversity, 2013
Measures of alpha diversity are more frequently used to detect environmental changes and subsequent impacts on biodiversity, while measures based on variability (beta diversity) are said to be more appropriate for detecting those impacts. Theory predicts
Annie Séguin, Dominique Gravel, Philippe Archambault   +2 more
doaj   +1 more source

Disentangling the beta-diversity in anuran parasite communities

Parasitology, 2020
AbstractThere is great heterogeneity in parasite communities among hosts, understanding the nature and drivers of such variations is still a great scientific quest. Here, we analyse the variation in parasite communities by addressing the following questions: (i) What is the beta-diversity component (nestedness or turnover) that most contributes to beta
Elvira D'Bastiani, Karla M. Campião
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Genotypic-Phenotypic Diversity in Beta Thalassemia

Mediterranean Journal of Hematology and Infectious Diseases, 2014
The remarkable variability in clinical severity of the thalassemia reflects both genetic and environmental factors. It is becoming apparent that the genetic element involves many loci, some of which are directly involved with the basic defect in globin ...
Ravindra Kumar, Vandana Arya
doaj  

Different facets of alpha and beta diversity of benthic diatoms along stream watercourse in a large near‐natural catchment

Ecology and Evolution
Understanding the processes and mechanisms that shape the distribution patterns and variations of biodiversity along spatial gradients continues to be a priority for ecological research. We focused on the biodiversity of benthic diatom communities within
Naicheng Wu, Guohao Liu, Xinxin Qi, Zongwei Lin, Yixia Wang, Yaochun Wang, Yuying Li, Collins Oduro, Sangar Khan, Shuchan Zhou, Tianjiang Chu   +10 more
doaj   +1 more source

Clinical Features of Rapidly Progressive Alzheimer's Disease [PDF]

, 2010
Objective: To characterize clinical features, CSF biomarkers and genetic polymorphisms of patients suffering from a rapidly progressing subtype of Alzheimer's dementia (rpAD).
Ahsen, Nico von, Krack, Lennart, Kretzschmar, Hans, Meissner, Bettina, Redyk, Katharina, Roeber, Sigrun, Schmidt, Christian, Zerr, Inga   +7 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Genetic and phenotypic characterization of intestinal spirochetes colonizing chickens and allocation of known pathogenic isolates to three distinct genetic groups [PDF]

, 1997
Infection with intestinal spirochetes has recently been recognized as a cause of lost production in the poultry industry. Little is known about these organisms, so a collection of 56 isolates originating from chickens in commercial flocks in Australia ...
McLaren, A.J., Trott, D.J., Swayne, D.E, Oxberry, S.L., Hampson, D.J.   +4 more
core   +1 more source

Emergent global oscillations in heterogeneous excitable media: The example of pancreatic beta cells

, 2000
Using the standard van der Pol-FitzHugh-Nagumo excitable medium model I demonstrate a novel generic mechanism, diversity, that provokes the emergence of global oscillations from individually quiescent elements in heterogeneous excitable media.
A. Herchuelz, A. Jörns, A. Sherman, A.N. Zaikin, A.S. Pikovsky, A.T. Winfree, A.T. Winfree, A.T. Winfree, B. van der Pol, C. Huygens, D. Salomon, D.G. Pipeleers, E. Grapengiesser, E. Meron, F. Schuit, G.B. Ermentrout, H. Heimberg, H. Sakaguchi, H. Sakaguchi, H.P. Meissner, J.E. Truscott, J.H.E. Cartwright, J.H.E. Cartwright, J.J. Collins, J.S. Nagumo, Julyan H. E. Cartwright, K. Bar-Eli, K. Wiesenfeld, K. Wiesenfeld, L. Kramer, M. Feingold, M. Hiriart, M. Pérez-Armendáriz, M. Valdeomillos, P. Rorsman, P. Smolen, P.M. Dean, R.A. FitzHugh, R.A. FitzHugh, R.E. Mirollo, Y. Braiman, Y. Braiman, Y. Kuramoto, Y. Stefan   +43 more
core   +1 more source