Results 121 to 130 of about 546 (155)
Effect of acute anaerobic performance on zinc alpha 2 glycoprotein, apelin and lipasin levels. [PDF]
PeerJÜnver Ş +10 more
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First Trimester Hematological Indices in Gestational Diabetes Mellitus: A Meta-Analysis. [PDF]
J Endocr SocFirouzi F +5 more
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Emerging Regulation and Function of Betatrophin [PDF]
International Journal of Molecular Sciences, 2014 Betatrophin, also known as TD26/RIFL/lipasin/ANGPTL8/C19orf80, is a novel protein predominantly expressed in human liver. To date, several betatrophin orthologs have been identified in mammals. Increasing evidence has revealed an association between betatrophin expression and serum lipid profiles, particularly in patients with obesity or diabetes ...
Wei-Jan Chen +2 more
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High betatrophin in coronary patients protects from cardiovascular events
Atherosclerosis, 2020Betatrophin, also known as angiopoietin-like protein 8 (ANGPTL8) or lipasin, is a nutritionally-regulated mammalian-specific protein secreted by the liver and adipose tissue. Many conflicting data exist with respect to its association with type 2 diabetes mellitus (T2DM), insulin resistance, and lipid markers, but no data are available on its ...
Heinz Drexel +2 more
exaly +4 more sources
Evaluation of circulating betatrophin levels in gestational diabetes mellitus
Gynecological Endocrinology, 2015 Experimental data indicate that betatrophin plays a significant role in the regulation of lipid metabolism and glucose homeostasis. In recent years, considerable attention has focused on the relationship between betatrophin and diabetes mellitus in humans.
Onur Erol
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Betatrophin in Diabetes Mellitus: the Epidemiological Evidence in Humans
Current Diabetes Reports, 2015The prevalence of type 2 diabetes is increasing worldwide, and while numerous treatments exist, none of the current pharmacologic therapies is curative. Pharmacologic approaches that increase beta cell mass may present an avenue for actual cure. There have been numerous reports on factors that can induce beta cell proliferation in rodents, whereas ...
Daniel, Espes +3 more
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ANGPTL8 (betatrophin) role in diabetes and metabolic diseases
Diabetes/Metabolism Research and Reviews, 2017SummaryDiabetes is a major disease worldwide that is reaching epidemic levels. Its increased prevalence as well as its association with a high number of complications such as cardiovascular diseases, nephropathy, and retinopathy makes it an important disease for investigation.
Mohamed Abu‐Farha +2 more
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Diabetes, 2018
Betatrophin, also known as ANGPTL8, is secreted by liver and adipose tissue and plays an important role in glucose and lipid metabolism, but the mechanisms behind this remain unclear. Betatrophin is highly activated by active triiodothyronine (T3), a key player in metabolic control, which in turn is activated by bile acids (BA) via the BA-G-protein ...
ANDREAS LEIHERER +9 more
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Betatrophin, also known as ANGPTL8, is secreted by liver and adipose tissue and plays an important role in glucose and lipid metabolism, but the mechanisms behind this remain unclear. Betatrophin is highly activated by active triiodothyronine (T3), a key player in metabolic control, which in turn is activated by bile acids (BA) via the BA-G-protein ...
ANDREAS LEIHERER +9 more
openaire +1 more source
Circulation, 2015
Betatrophin (ANGPTL8), also known as “Lipasin” (lipoprotein lipase inhibitor), has been reported as a dual-regulator of glucose and lipid metabolism. Functional variant R59W in betatrophin gene is common in Japanese (minor allele 25%) compared with Caucasian (5%). Little is known about long-term impact of this gene variant, and also about the effect of
Atsushi Nohara +13 more
openaire +1 more source
Betatrophin (ANGPTL8), also known as “Lipasin” (lipoprotein lipase inhibitor), has been reported as a dual-regulator of glucose and lipid metabolism. Functional variant R59W in betatrophin gene is common in Japanese (minor allele 25%) compared with Caucasian (5%). Little is known about long-term impact of this gene variant, and also about the effect of
Atsushi Nohara +13 more
openaire +1 more source
Assessment of circulating betatrophin levels in intrahepatic cholestasis of pregnancy
The Journal of Maternal-Fetal & Neonatal Medicine, 2018Objective: To investigate maternal serum levels of betatrophin and their relationship with total bile acid (TBA) levels in patients with intrahepatic cholestasis of pregnancy (ICP).Materials and methods: Fifty-nine pregnant women with ICP (31 patients with severe and 28 patients with mild disease classifications) and 23 healthy women with uncomplicated
Özgür, Kara +6 more
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