Results 171 to 180 of about 1,252 (192)
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Betatrophin in Diabetes Mellitus: the Epidemiological Evidence in Humans
Current Diabetes Reports, 2015The prevalence of type 2 diabetes is increasing worldwide, and while numerous treatments exist, none of the current pharmacologic therapies is curative. Pharmacologic approaches that increase beta cell mass may present an avenue for actual cure. There have been numerous reports on factors that can induce beta cell proliferation in rodents, whereas ...
Daniel, Espes +3 more
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Circulation, 2015
Betatrophin (ANGPTL8), also known as “Lipasin” (lipoprotein lipase inhibitor), has been reported as a dual-regulator of glucose and lipid metabolism. Functional variant R59W in betatrophin gene is common in Japanese (minor allele 25%) compared with Caucasian (5%). Little is known about long-term impact of this gene variant, and also about the effect of
Atsushi Nohara +13 more
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Betatrophin (ANGPTL8), also known as “Lipasin” (lipoprotein lipase inhibitor), has been reported as a dual-regulator of glucose and lipid metabolism. Functional variant R59W in betatrophin gene is common in Japanese (minor allele 25%) compared with Caucasian (5%). Little is known about long-term impact of this gene variant, and also about the effect of
Atsushi Nohara +13 more
openaire +1 more source
Diabetes, 2018
Betatrophin, also known as ANGPTL8, is secreted by liver and adipose tissue and plays an important role in glucose and lipid metabolism, but the mechanisms behind this remain unclear. Betatrophin is highly activated by active triiodothyronine (T3), a key player in metabolic control, which in turn is activated by bile acids (BA) via the BA-G-protein ...
ANDREAS LEIHERER +9 more
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Betatrophin, also known as ANGPTL8, is secreted by liver and adipose tissue and plays an important role in glucose and lipid metabolism, but the mechanisms behind this remain unclear. Betatrophin is highly activated by active triiodothyronine (T3), a key player in metabolic control, which in turn is activated by bile acids (BA) via the BA-G-protein ...
ANDREAS LEIHERER +9 more
openaire +1 more source
Assessment of circulating betatrophin levels in intrahepatic cholestasis of pregnancy
The Journal of Maternal-Fetal & Neonatal Medicine, 2018Objective: To investigate maternal serum levels of betatrophin and their relationship with total bile acid (TBA) levels in patients with intrahepatic cholestasis of pregnancy (ICP).Materials and methods: Fifty-nine pregnant women with ICP (31 patients with severe and 28 patients with mild disease classifications) and 23 healthy women with uncomplicated
Özgür, Kara +6 more
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Betatrophin in nonalcoholic fatty liver disease
European Journal of Gastroenterology & Hepatology, 2016Hasan, Gurel, Teoman, Dogru
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Association between circulating betatrophin levels and T2DM: a meta-analysis
Minerva EndocrinologyThe association between betatrophin level and type 2 diabetes mellitus (T2DM) is a subject of controversy, and the reasons for conflicting results have been poorly explained. To address this gap, we conducted a meta-analysis of relevant studies to obtain a more comprehensive estimate and draw a more accurate conclusion.This study included literature ...
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Increased Betatrophin and WISP1 Levels in Gestational Diabetes
2016Soc Reprod ...
Ersoy, Gulcin Sahin +2 more
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Betatrophin – A new insight into lipid homeostasis
Atherosclerosis, 2017Eva Bace +5 more
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Increased circulating levels of betatrophin in individuals with long-standing type 1 diabetes
Diabetologia, 2013Daniel Espes, Joey Lau, Per-Ola Carlsson
exaly