Results 11 to 20 of about 29,488 (242)

Beti Bachao Beti Padhao Campaign: An Attempt to Social Empowerment

Indian Journal of Community and Family Medicine, 2020
In world, almost half of the total population made up of women but they still lag behind men in a lot of areas. The skewed child sex ratio is a prime indicator of women disempowerment, lack of value attached to her and disrespect. Over few years, a significant fraction of number of women has been at the receiving end of discrimination and exploitation.
Ramesh Verma, Rohit Dhaka, Ginni Agrawal
  +7 more sources

Beti Bachao Beti Padhao Scheme, Haryana: Improvement in sex ratio at birth and other achievements

Indian Journal of Community and Family Medicine, 2021
Yogender Malik
doaj   +2 more sources

Highly effective combination of BRG1/BRM inhibitor with BET inhibitor or decitabine for high-risk MECOM-rearranged AML. [PDF]

Hemasphere
Abstract In AML with 3q26.2 rearrangements (r) the distal GATA2 hematopoietic enhancer becomes aberrantly relocated leading to activation of EVI1 expression. EVI1 is a transcriptional regulator that plays a role in proliferation and maintenance of a stem cell‐like phenotype in AML.
Fiskus W, Mill CP, Piel J, Collins M, Hentemann M, Cuglievan B, Birdwell CE, Das K, Davis JA, Hou H, Jain A, Malovannaya A, Flores LB, Kadia TM, Daver N, Sasaki K, Takahashi K, Hammond D, Wang J, Loghavi S, Su X, DiNardo CD, Delwel R, Bhalla KN.   +23 more
europepmc   +2 more sources

Biological Effects of BET Inhibition by OTX015 (MK-8628) and JQ1 in NPM1-Mutated (NPM1c) Acute Myeloid Leukemia (AML)

Biomedicines, 2021
BET inhibitors (BETi) including OTX015 (MK-8628) and JQ1 demonstrated antileukemic activity including NPM1c AML cells. Nevertheless, the biological consequences of BETi in NPM1c AML were not fully investigated.
Hanane Djamai, Jeannig Berrou, Mélanie Dupont, Marie-Magdelaine Coudé, Marc Delord, Emmanuelle Clappier, Alice Marceau-Renaut, Anna Kaci, Emmanuel Raffoux, Raphaël Itzykson, Caroline Berthier, Hsin-Chieh Wu, Rita Hleihel, Ali Bazarbachi, Hugues de Thé, André Baruchel, Claude Gardin, Hervé Dombret, Thorsten Braun   +18 more
doaj   +1 more source

Bir Aşk Söyleminden Parçalar Işığında Türk Hikayelerine Kısa Bir Bakış

Mukaddime, 2023
Çalışmamız Roland Barthes’in “Bir Aşk Söyleminden Parçalar” adlı metni temelinde Türk hikayelerinin kısa bir değerlendirmesidir. Barthes’in rastlantısal ve düzenli okumalar tekniği kullanılarak yapılan incelemede toplam yirmi yedi başlık tespit edilmiş ...
Serdal Kara
doaj   +1 more source

Oxygen reduction reaction on platinum single-crystal electrodes modified with protonic ionic liquid

Electrochemistry Communications, 2022
The oxygen reduction reaction (ORR) on the low- and high-index planes of Pt modified with a protonic ionic liquid ([7-methyl-1,5,7-triazabicyclo(4.4.0)dec-5-ene][bis(pentafluoroethylsulfonyl)imide], referred to here as [MTBD][beti]) was studied in 0.1 M ...
Rui Suzuki, Masashi Nakamura, Nagahiro Hoshi   +2 more
doaj   +1 more source

Gene therapy in transfusion-dependent non-β0/β0 genotype β-thalassemia: first real-world experience of beti-cel. [PDF]

Blood Adv
Mirza A, Ritsert ML, Tao G, Thakar H, Lobitz S, Heine S, Koscher L, Dürken M, Schmitt A, Schmitt M, Pavel P, Laier S, Jakoby D, Greil J, Kunz J, Kulozik A.   +15 more
europepmc   +2 more sources

Novel regulatory mechanism of choline-O-sulfate and choline catabolism by two BetIs in Alphaproteobacteria. [PDF]

Appl Environ Microbiol
Liu J-R, Li Z-K, Wang M-C, Wang N, Wang Z-Q, Li F-F, Chen Y, Zhang Y-Z, Fu H-H.   +8 more
europepmc   +2 more sources

A Novel Acetylation-Immune Subtyping for the Identification of a BET Inhibitor-Sensitive Subgroup in Melanoma

Pharmaceuticals, 2023
Background: There have been significant advancements in melanoma therapies. BET inhibitors (BETis) show promise in impairing melanoma growth. However, identifying BETi-sensitive melanoma subtypes is challenging.
Liuying Wang, Liuchao Zhang, Shuang Li, Lei Cao, Kang Li, Weiwei Zhao   +5 more
doaj   +1 more source

Targeting radioresistance and replication fork stability in prostate cancer

JCI Insight, 2022
The bromodomain and extraterminal (BET) family of chromatin reader proteins bind to acetylated histones and regulate gene expression. The development of BET inhibitors (BETi) has expanded our knowledge of BET protein function beyond transcriptional ...
Xiangyi Li, GuemHee Baek, Suzanne Carreira, Wei Yuan, Shihong Ma, Mia Hofstad, Sora Lee, Yunpeng Gao, Claudia Bertan, Maria de los Dolores Fenor de la Maza, Prasanna G. Alluri, Sandeep Burma, Benjamin P.C. Chen, Ganesh V. Raj, Johann de Bono, Yves Pommier, Ram S. Mani   +16 more
doaj   +1 more source