Results 71 to 80 of about 104,823 (289)
, 2017 Background: To determine the appropriate time of concomitant chemotherapy administration after antiangiogenic treatment, we investigated the timing and effect of bevacizumab administration on vascular normalization of metastatic brain tumors in breast ...
陳偉武;盧彥伸;林璟宏;施庭芳;許昭禹;吳佩芳;鄭安理;陳邦斌;魏淑圓;游治維;林季宏 +1 more
core +1 more source
Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation
Advanced Science, EarlyView.An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng +10 more
wiley +1 more source
Cancer Medicine, 2019 Purpose Combination of biological therapy and chemotherapy improves the survival of patients with metastatic colorectal cancer (mCRC). However, the optimal biological therapy sequence remains unclear.
Hung‐Chih Hsu +7 more
doaj +1 more source
Liver Cancer, 2022 Introduction: In the Phase 3 IMbrave150 trial (NCT03434379), atezolizumab + bevacizumab demonstrated a clinically meaningful survival benefit over sorafenib in patients with unresectable hepatocellular carcinoma (HCC), including those with hepatitis B ...
Chiun Hsu +12 more
doaj +1 more source
Bevacizumab in the treatment of ovarian cancer [PDF]
, 2011 Ramez N Eskander1, Leslie M Randall21Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California Irvine Medical Center, Orange, CA, USA; 2Division of Gynecologic Oncology, Department of Obstetrics and Gynecology ...
Leslie Randall +4 more
core +1 more source
Advanced Science, EarlyView.This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma +10 more
wiley +1 more source
Storage stability of bevacizumab in polycarbonate and polypropylene syringes [PDF]
, 2015 Purpose To compare and examine the storage stability of compounded bevacizumab in polycarbonate (PC) and polypropylene (PP) syringes over a 6-month period.
Froome, Andrew +4 more
core
, 2017 Background: We aimed to evaluate early clinical and pathological results for treating locally advanced rectal cancer with bevacizumab and neoadjuvant concurrent chemoradiotherapy using the technique of prone-position volumetric modulated arc therapy and ...
林育麟;成佳憲;王嘉檇;陳育瑄;蔡巧琳;孫家棟;梁金銅 +1 more
core +1 more source
Advanced Science, EarlyView.IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng +7 more
wiley +1 more source
Gravity influences bevacizumab distribution in an undisturbed balanced salt solution in vitro.
PLoS ONE, 2019 PurposeThe effects of gravity on bevacizumab or the recommended head position after intraocular bevacizumab injection have not been reported. To evaluate the effect of gravity on bevacizumab in vitro, we added bevacizumab to the upper part of a test tube
Rae Young Kim, Soonil Kwon, Ho Ra
doaj +1 more source