Results 81 to 90 of about 104,823 (289)

Perfusion imaging of colorectal liver metastases treated with bevacizumab and stereotactic body radiotherapy

Physics and Imaging in Radiation Oncology, 2018
Stereotactic body radiotherapy (SBRT) and bevacizumab are used in the treatment of colorectal liver metastases. This study prospectively evaluated changes in perfusion of liver metastases in seven patients treated with both bevacizumab and SBRT ...
Jay S. Detsky, Laurent Milot, Yoo-Joung Ko, Pablo Munoz-Schuffenegger, William Chu, Gregory Czarnota, Hans T. Chung   +6 more
doaj   +1 more source

Bevacizumab with Erlotinib as First-line Therapy in Asian Patients with Advanced Hepatocellular Carcinoma: A Multicenter Phase II Study

, 2014
Objectives: The bevacizumab/erlotinib combination was reported with high clinical activity for advanced hepatocellular carcinoma (HCC) by a phase II study conducted in the USA.
邵幼雲 ;鄭安理 ;徐志宏 ;許駿 ;孫家棟, Hsu, Chih-Hung;Kang, Yoon Koo;Yang, Tsai-Shen;Shun, Chia-Tung;Shao, Yu-Yun;Su, Wu-Chou;Sandoval-Tan, Jennifer;Chiou, Tzeon-Jye;Jin, Kate;Hsu, Chiun;Cheng, Ann-Lii   +1 more
core   +1 more source

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

Efferent therapy in the first-line drug treatment of metastatic colorectal cancer

Медицинский совет, 2018
The aim of this study is to analyse the efficacy of efferent therapy (hemosorption) as part of drug treatment in patients with metastatic colorectal cancer (mCRC) based on the use of standard first-line chemotherapy combined with the bevacizumab ...
Z. S. Kotova, T. Yu. Semiglazova, I. A. Baldueva, D. H. Latipova, D. O. Yurlov, V. V. Semiglazov, G. M. Teletaeva, A. V. Novik, A. I. Semenova, S. A. Protsenko   +9 more
doaj   +1 more source

Technical Feasibility of Laparoscopic Total Mesorectal Excision for Patients with Low Rectal Cancer after Concurrent Radiation and Chemotherapy with Bevacizumab Plus Folfox

, 2012
This study aimed to evaluate the technical feasibility of laparoscopic total mesorectal excision TME for the treatment of low rectal cancer after concurrent chemoradiation therapy CCRT with bevacizumab and FOLFOX.
梁金銅;賴鴻?, Liang, Jin-Tung; Lai, Hong-Shiee; Cheng, Kuo-Wei   +1 more
core   +1 more source

Advances in Cancer Immunotherapy for Solid Tumors

Advanced Science, EarlyView.
Cancer immunotherapy for solid tumors is rapidly evolving beyond classical checkpoint blockade toward more precise strategies. Emerging checkpoint targets, bispecific antibodies, antibody–drug conjugate combinations, personalized vaccines, cellular therapies, and engineered cytokines are expanding therapeutic possibilities, while biomarker‐guided ...
Shira Gabizon‐Peretz, Harriet M. Kluger   +1 more
wiley   +1 more source

Efficacy and Tolerability of Bevacizumab Plus Capecitabine as First-Line Therapy in Patients with Advanced Hepatocellular Carcinoma

, 2010
Molecularly targeted agents with anti-angiogenic activity, including bevacizumab, have demonstrated clinical activity in patients with advanced /metastatic hepatocellular carcinoma (HCC).
徐志宏;許駿;陳培哲;林宗哲;趙祖怡;鄭安理, P-J Chen, C Hsu, H C Toh, A-L Cheng, Z-Z Lin, L-T Hsiao, HSU, CHIH-HUNG;HSU, CHIUN;CHEN, PEI-JER;LIN, ZONG-ZHE;CHAO, TSU-YI;CHENG, ANN-LII, C-H Hsu, T-S Yang, R J Epstein, T-Y Chao   +11 more
core   +1 more source

Primary Tumor Resection in Patients With Unresectable Metastatic Colorectal Cancer: A Systematic Review and Meta‐Analysis

Annals of Gastroenterological Surgery, EarlyView.
This systematic review and meta‐analysis evaluated the role of primary tumor resection (PTR) in asymptomatic patients with unresectable metastatic colorectal cancer. Across 17 eligible studies including 9317 patients, PTR did not improve overall or progression‐free survival compared with chemotherapy alone.
Junpei Takashima, Hirotoshi Kobayashi, Daisuke Fujimoto, Fumihiko Miura   +3 more
wiley   +1 more source

Surgical Outcomes and Recurrence Management in Borderline Resectable Hepatocellular Carcinoma: Implications for Multidisciplinary Strategies

Annals of Gastroenterological Surgery, EarlyView.
Multivariate analysis identified that up‐to‐7 out (p < 0.001), lymph node metastasis (p < 0.001), and non‐anatomical resection (p = 0.02) were independent predictors of cancer recurrence, while older age (p = 0.01), Child‐Pugh B (p < 0.001), up‐to‐7 out (p = 0.01), macrovascular invasion (p = 0.01), and lymph node metastasis (p < 0.001) were ...
Koichiro Haruki, Kenei Furukawa, Munetoshi Akaoka, Yuto Yamahata, Shinji Onda, Yoshihiro Shirai, Masashi Tsunematsu, Tomohiko Taniai, Michinori Matsumoto, Toru Ikegami   +9 more
wiley   +1 more source

Risk of severe pulmonary embolism in cancer patients receiving bevacizumab: Results from a meta-analysis of published and unpublished data

Tumor Biology, 2017
To evaluate the association between severe pulmonary embolism events and bevacizumab, we conducted the first meta-analysis evaluating the incidence and risk of pulmonary embolism associated with bevacizumab-based therapy.
Meidan Liu, Yayuan Zheng, Zuguang Chen, Yumiao Qiu, Zhanchun Pan, Zitao Cai, Yapeng Shi, Junfen Cheng, Weimin Yao   +8 more
doaj   +1 more source