Results 61 to 70 of about 104,823 (289)
Frontiers in Immunology, 2020 Highly sensitive reporter-gene assays have been developed that allow both the direct vascular endothelial growth factor (VEGF) neutralizing activity of bevacizumab and the ability of bevacizumab to activate antibody dependent cellular cytotoxicity (ADCC)
Christophe Lallemand +8 more
doaj +1 more source
Thiolated Polymers in 3D Bioprinting: Control of Gelation
Advanced Materials, EarlyView.Thiolated polymers are established as programmable bioinks for 3D bioprinting, integrating versatile crosslinking chemistries with redox‐responsive control. This work demonstrates how molecular design and external triggers define gelation kinetics, printability windows, and structural fidelity, enabling stable, high‐resolution constructs and advancing ...
Soheil Haddadzadegan +2 more
wiley +1 more source
, 2017 Background/purpose: Patients with leptomeningeal carcinomatosis (LC) from breast cancer is generally resistant to systemic chemotherapy. Bevacizumab may increase intratumor concentration of the chemotherapeutic agents through vascular normalization ...
盧彥伸;林璟宏;詹一秀;陳怡君;鄭安理;林季宏 +1 more
core +1 more source
Advanced Science, EarlyView.Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang +14 more
wiley +1 more source
Evaluation of a New Potential Bevacizumab Biosimilar in Corneal Neovascularization
Türk Oftalmoloji DergisiObjectives: To compare the antiangiogenic effects of bevacizumab and a new potential bevacizumab biosimilar (anti-human VEGF GU01) on suture-induced corneal neovascularization (CNV) in rabbits. Materials and Methods: CNV was induced in the right eyes of
Armağan Özgür +4 more
doaj +1 more source
Clinical Medicine Insights: Oncology, 2008 Background Bevacizumab and irinotecan may represent one of the most active treatments in progressive malignant glioma. Limited published experience with bevacizumab in patients with CNS tumors raises concerns regarding toxicity, particularly in regards ...
Tina Mayer +2 more
doaj +1 more source
Bevacizumab increases the risk of anastomosis site leakage in metastatic colorectal cancer
Frontiers in Oncology, 2022 BackgroundBevacizumab is a humanized monoclonal antibody against vascular endothelial growth factor and is used in combination with first-line chemotherapy in the treatment of metastatic colorectal cancer.
Seijong Kim +9 more
doaj +1 more source
, 2009 : Background To report the effect of intravitreal injection of bevacizumab and gas for the treatment of diabetic premacular hemorrhage with active fibrovascular proliferation.
施智偉;楊中美;陳慕師;王宗仁 +1 more
core +1 more source
Advanced Science, EarlyView.This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
IJRETINA (International Journal of Retina), 2021 Introduction: To evaluate whether the combination of diclofenac eye drops and bevacizumab intravitreal injection would provide additional benefits over bevacizumab alone in the treatment of naïve diabetic macular edema (DME).
Melvina Nidya Sandra +6 more
doaj +1 more source