Results 51 to 60 of about 110,931 (189)

Evaluation of the efficacy and tolerability of bevacizumab-based treatments in recurrent primary brain tumors: a multicenter real-world Turkish Oncology Group (TOG) study

BMC Cancer
Background Bevacizumab is widely used for recurrent high-grade glioma, but the real-world effectiveness of bevacizumab with or without irinotecan remains uncertain. We evaluated outcomes of bevacizumab-based regimens in a large multicenter Turkish cohort.
Zehra Sucuoğlu İşleyen, Şaban Seçmeler, Abdullah Sakin, Şener Cihan, Mehmet Beşiroğlu, Seda Kahraman, Melek Karakurt Eryılmaz, Esra Zeynelgil, Eda Çalışkan Yıldırım, Engin Kut, Nilay Şengül, Fatma Paksoy Türköz, Özkan Alan, Özlem Özkul, Selver Işık, Feride Yılmaz, Ahmet Gülmez, Sema Türker, Gökhan Karakaya, Meral Günaldı, Leyla Özer, Asude Aksoy, Fatih Karataş, Teoman Sakalar, Derya Demirtaş Esmer, Fatih Teker, Necla Demir, Özgecan Dülgar, Serdar Turhal, Hacı Mehmet Türk, Kayhan Ertürk, Emir Çelik, M. Mustafa Atcı   +32 more
doaj   +1 more source

CENTRAL MACULAR THICKNESS AFTER COMBINED THERAPY OF BEVACIZUMAB INTRAVITREAL INJECTION AND TOPICAL DICLOFENAC COMPARED WITH BEVACIZUMAB INTRAVITREAL INJECTION ALONE IN DIABETIC MACULAR EDEMA

IJRETINA (International Journal of Retina), 2021
Introduction: To evaluate whether the combination of diclofenac eye drops and bevacizumab intravitreal injection would provide additional benefits over bevacizumab alone in the treatment of naïve diabetic macular edema (DME).
Melvina Nidya Sandra, Yumni Shabrina, Tri Wahyu Widayanti, Retno Ekantini, Agus Supartoto, Muhammad Bayu Sasongko, Supanji Haryanto   +6 more
doaj   +1 more source

Bevacizumab Is Not Toxic to Retinal Ganglion Cells after Repeated Intravitreal Injection

, 2011
Purpose: The cytotoxicity of single and repeated administration of bevacizumab to retinal ganglion cells was studied in vivo and in vitro. Methods: Rats received single or repeated injections of 125 mu g of bevacizumab into the vitreous cavity of the ...
CHENG, CHENG-KUO;PENG, PAI-HUEI;TIEN, LU-TAI;CHEN, CHAU-FONG;LEE, YIH-JING, 鄭成國;彭百慧;田履黛;陳朝峰;李憶菁   +1 more
core   +1 more source

Hepatic Events and Viral Kinetics in Hepatocellular Carcinoma Patients Treated With Atezolizumab Plus Bevacizumab

Liver Cancer, 2022
Introduction: In the Phase 3 IMbrave150 trial (NCT03434379), atezolizumab + bevacizumab demonstrated a clinically meaningful survival benefit over sorafenib in patients with unresectable hepatocellular carcinoma (HCC), including those with hepatitis B ...
Chiun Hsu, Michel Ducreux, Andrew X. Zhu, Shukui Qin, Masafumi Ikeda, Tae-You Kim, Peter R. Galle, Richard S. Finn, Ethan Chen, Ning Ma, Youyou Hu, Lindong Li, Ann-Lii Cheng   +12 more
doaj   +1 more source

Bevacizumab Pretreatment in Vitrectomy with Silicone Oil for Severe Diabetic Retinopathy

, 2011
Purpose: To evaluate the effects of intravitreal bevacizumab pretreatment in vitrectomy with silicone oil infusion for severe diabetic retinopathy. Methods: Forty-one eyes (39 patients) that underwent primary vitrectomy with silicone oil tamponade for ...
葉伯廷;楊中美;林友祺;陳慕師;楊長豪, YEH, PO-TING;YANG, CHUNG-MAY;LIN, YU-CHI;CHEN, MUH-SHY;YANG, CHANG-HAO   +1 more
core   +1 more source

A Single Institution's Experience with Bevacizumab in Combination with Cytotoxic Chemotherapy in Progressive Malignant Glioma

Clinical Medicine Insights: Oncology, 2008
Background Bevacizumab and irinotecan may represent one of the most active treatments in progressive malignant glioma. Limited published experience with bevacizumab in patients with CNS tumors raises concerns regarding toxicity, particularly in regards ...
Tina Mayer, Jill Lacy, Joachim Baehring M.D.   +2 more
doaj   +1 more source

A pilot study to determine the timing and effect of bevacizumab on vascular normalization of metastatic brain tumors in breast cancer

, 2017
Background: To determine the appropriate time of concomitant chemotherapy administration after antiangiogenic treatment, we investigated the timing and effect of bevacizumab administration on vascular normalization of metastatic brain tumors in breast ...
陳偉武;盧彥伸;林璟宏;施庭芳;許昭禹;吳佩芳;鄭安理;陳邦斌;魏淑圓;游治維;林季宏, Chen, Bang-Bin;Lu, Yen-Shen;Lin, Ching-Hung;Chen, Wei-Wu;Wu, Pei-Fang;Hsu, Chao-Yu;Yu, Chih-Wei;Wei, Shwu-Yuan;Cheng, Ann-Lii;Shih, Tiffany Ting-Fang   +1 more
core   +1 more source

Bevacizumab‐associated intestinal perforation and perioperative complications in patients receiving bevacizumab

Annals of Gastroenterological Surgery, 2020
Aim The purposes of this study are to present cases of emergency surgery in which gastrointestinal perforation occurred during bevacizumab administration, consider the indications for emergency surgery, and examine the safety of scheduled surgery after a
Toshiaki Yoshimoto, Kozo Yoshikawa, Jun Higashijima, Tomohiko Miyatani, Takuya Tokunaga, Masaaki Nishi, Chie Takasu, Hideya Kashihara, Yukako Takehara, Mitsuo Shimada   +9 more
doaj   +1 more source

Quantification of Bevacizumab Activity Following Treatment of Patients With Ovarian Cancer or Glioblastoma

Frontiers in Immunology, 2020
Highly sensitive reporter-gene assays have been developed that allow both the direct vascular endothelial growth factor (VEGF) neutralizing activity of bevacizumab and the ability of bevacizumab to activate antibody dependent cellular cytotoxicity (ADCC)
Christophe Lallemand, Rosa Ferrando-Miguel, Michael Auer, Sarah Iglseder, Theresa Czech, Anouk Gaber-Wagener, Franziska Di Pauli, Florian Deisenhammer, Michael G. Tovey   +8 more
doaj   +1 more source

Advantages of Tyrosine Kinase Anti-Angiogenic Cediranib over Bevacizumab: Cell Cycle Abrogation and Synergy with Chemotherapy

Pharmaceuticals, 2021
Angiogenesis plays a crucial role in tumor development and metastasis. Both bevacizumab and cediranib have demonstrated activity as single anti-angiogenic agents in endometrial cancer, though subsequent studies of bevacizumab combined with chemotherapy ...
Jianling Bi, Garima Dixit, Yuping Zhang, Eric J. Devor, Haley A. Losh, Andreea M. Newtson, Kristen L. Coleman, Donna A. Santillan, Thorsten Maretzky, Kristina W. Thiel, Kimberly K. Leslie   +10 more
doaj   +1 more source