Results 71 to 80 of about 72,341 (282)
The Evolution of the Neural Basic Helix-Loop-Helix Proteins
The Scientific World Journal, 2001 Basic Helix-Loop-Helix (bHLH) transcription factors control various aspects of the formation of the nervous system in the metazoans. In Drosophila some bHLH (such as the achaete-scuteatonal, and amos genes) act as proneural genes, directing ectodermal ...
Michel Vervoort, Valerie Ledent
doaj +1 more source
Czech Journal of Genetics and Plant Breeding, 2022 The basic Helix-Loop-Helix (bHLH) superfamily is the most widespread family of transcription factors in eukaryotic organisms, which can activate the expression of genes by interacting with specific promoters in the genes.
Noor Muhammad +5 more
doaj +1 more source
Cis-regulatory basis of sister cell type divergence in the vertebrate retina [PDF]
, 2019 Multicellular organisms evolved via repeated functional divergence of transcriptionally related sister cell types, but the mechanisms underlying sister cell type divergence are not well understood.
Corbo, Joseph C +4 more
core +3 more sources
The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus
Advanced Science, EarlyView.BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang +8 more
wiley +1 more source
Scientific Reports, 2017 Basic helix-loop-helix (bHLH) proteins, which are characterized by a conserved bHLH domain, comprise one of the largest families of transcription factors in both plants and animals, and have been shown to have a wide range of biological functions ...
Jinhua Yang +8 more
doaj +1 more source
Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle. [PDF]
, 1996 Viral oncoproteins that inactivate the retinoblastoma tumor suppressor protein (pRb) family both block skeletal muscle differentiation and promote cell cycle progression.
Jacks, T +3 more
core
Genome-wide survey and expression analysis of the bHLH-PAS genes in the amphioxus Branchiostoma floridae reveal both conserved and diverged expression patterns between cephalochordates and vertebrates [PDF]
, 2014 BACKGROUND: The bHLH-PAS transcription factors are found in both protostomes and deuterostomes. They are involved in many developmental and physiological processes, including regional differentiation of the central nervous system, tube-formation, hypoxia
Jr-Kai Yu, Kun-Lung Li, Tsai-Ming Lu
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Advanced Science, EarlyView.This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang +10 more
wiley +1 more source
Transcriptome pathways unique to dehydration tolerant relatives of modern wheat [PDF]
, 2009 Among abiotic stressors, drought is a major factor responsible for dramatic yield loss in agriculture. In order to reveal differences in global expression profiles of drought tolerant and sensitive wild emmer wheat genotypes, a previously deployed shock ...
AN Olsen +53 more
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RFP represses transcriptional activation by bHLH transcription factors [PDF]
Oncogene, 2005 Basic helix-loop-helix (bHLH) transcription factors play a pivotal role in the regulation of tumorigenesis, and also in a wide range of other developmental processes in diverse species from yeast to humans. Here we demonstrate for the first time that Ret finger protein (RFP), a member of the TRIM family of proteins initially identified as a recombined ...
Adrian J C, Bloor +4 more
openaire +2 more sources