Results 221 to 230 of about 63,274 (284)

DEC1 Deficiency Attenuates Breast Cancer‐Induced Osteolytic Destruction by Suppression of Cancer‐Associated Fibroblast Differentiation

Cancer Medicine, Volume 15, Issue 5, May 2026.
Schematic diagram of the mechanism by which DEC1 deficiency attenuates breast cancer‐induced osteolytic destruction through suppression of cancer‐associated fibroblast differentiation. ABSTRACT Background Cancer‐associated fibroblasts (CAFs) in the bone microenvironment play a key role in breast cancer (BC) osteolytic bone metastases.
Zhiyi Qiang, Ying Huo, Lan Lin, Kaiao Chen, Wei Liu, Jian Yang   +5 more
wiley   +1 more source

The bHLH transcription factor gene EGL3 accounts for the natural diversity in Arabidopsis fruit trichome pattern and morphology. [PDF]

Plant Physiol
Méndez-Vigo B, Arteaga N, Murillo-Sánchez A, Alba S, Alonso-Blanco C.   +4 more
europepmc   +1 more source

Integrative Metabolomic and Transcriptomic Profiling Reveals the Chemical and Molecular Basis for Aroma Divergence in Isatis Fruits

Food Frontiers, Volume 7, Issue 3, May 2026.
Integrative metabolomic and transcriptomic analyses revealed the chemical and molecular basis of aroma divergence in fruits of three Isatis species. Distinct volatile profiles and 44 key aroma‐active compounds defined species‐specific sensory characteristics, while co‐expression analysis identified NAC transcription factors and lipid‐derived pathway ...
Rong Chen, Yan Qing, Xiaoshan Geng, Qiaoyun Cai, Lili Wang, Fanglin Liu, Huijun Cheng, Yude Peng, Chunfeng Tang, Huaxi Huang, Qin Liu   +10 more
wiley   +1 more source

Genome- and Transcriptome-Wide Characterization and Expression Analyses of bHLH Transcription Factor Family Reveal Their Relevance to Salt Stress Response in Tomato. [PDF]

Plants (Basel)
Zhang J, Liu X, Yin Z, Zhao T, Du D, Li J, Zhu M, Sun Y, Pan Y.   +8 more
europepmc   +1 more source

Single‐Cell Analysis Identified a Recurrent Malignant‐Associated Transcriptional State in Colorectal Cancer

Cancer Science, Volume 117, Issue 5, Page 1397-1411, May 2026.
Colorectal cancer (CRC) shows high molecular heterogeneity, yet single‐cell data from Japanese patients are limited. We performed scRNA‐seq on tumors and adjacent normal tissues from four Japanese CRC patients and identified a shared malignant cell cluster with high KCNQ1OT1 expression and reduced RASSF6 levels.
Sadahiro Iwabuchi, Kentaro Sawada, Motohiro Kojima, Miho Ozawa, Hiroya Taniguchi, Hideaki Bando, Kazumi Abe, Yuta Kuze, Kiyomi Imamura, Yukie Kashima, Yoshihiko Hirohashi, Atsushi Tajima, Toshihiko Torigoe, Yutaka Suzuki, Takayuki Yoshino, Shinichi Hashimoto   +15 more
wiley   +1 more source

A novel bHLH transcription factor PlLHL1 targets <i>PlLAC15</i> to negatively regulate stem strength by inhibiting syringyl lignin deposition in herbaceous peony. [PDF]

Hortic Res
Liu Z, Yin Y, Zuo S, Zhao M, Tao J, Tang Y, Zhao D.   +6 more
europepmc   +1 more source

A natural variation within duplicated AsWRKY49‐D2 drives the subgenomic functional divergence of homeologs in salt response of allohexaploid oats

Journal of Integrative Plant Biology, Volume 68, Issue 5, Page 1367-1383, May 2026.
Transcriptome analysis of oats under salt stress identified ten important salt‐responsive transcription factor families, which show extensive functional divergence among three oat subgenomes. Further integration with a genome‐wide association study under salt stress identified the AsWRKY49‐D2 gene, whose elite haplotype holds substantial potential for ...
Cailian Du, Yange Yun, Wenjia Li, Xiaolu Wu, Xingyu Liu, Minghao Li, Yingying Li, Shuhui Wang, Wei Li, Qiang He, Zhizhong Gong, Huilong Du, Qingbin Sun   +12 more
wiley   +1 more source

The Basic Helix–Loop–Helix Transcription Factors UvBhlh1 and UvBhlh6 Coordinate Virulence in the Rice False Smut Fungus Ustilaginoidea virens

Molecular Plant Pathology, Volume 27, Issue 5, May 2026.
Transcription factors UvBhlh1 and UvBhlh6 are essential for early infection and virulence in Ustilaginoidea virens. These two proteins form a heterodimer that cooperatively regulates downstream target genes during pathogenesis. ABSTRACT Ustilaginoidea virens is the causal agent of rice false smut, a devastating and globally widespread fungal disease ...
Huijuan Cao, Hao Gong, Xiaohong Huang, Jialin Lei, Mina Yu, Xiayan Pan, Tianqiao Song, Junjie Yu, Zhongqiang Qi, Yan Du, Rongsheng Zhang, Yongfeng Liu   +11 more
wiley   +1 more source

Two mutations in the same MYC-bHLH transcription factor cause segregation of purple coloration of stolons and seed heads in <i>Zoysia japonica</i> × <i>Zoysia matrella</i> F₂ and F₁ populations. [PDF]

Hortic Res
Pradhan S, Zhao J, Spiekerman JJ, Bennetzen EM, Khanal S, Yu X, Milla-Lewis S, Conner J, Schwartz BM, Devos KM.   +9 more
europepmc   +1 more source

Serial Spatial Transcriptomes Reveal Regulatory Transitions in Maize Leaf Development

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2787-2810, May 2026.
ABSTRACT Plant leaves originate from the shoot apical meristem (SAM) and undergo a developmental process of highly coordinated gene expression regulation. To date, only a few key regulators have been identified and characterised, so the gene expression cascades responsible for leaf cell specification and differentiation from SAM remain largely elusive.
Chi‐Chih Wu, Ludvig Larsson, Kun‐Ting Hsieh, Chun‐Ping Yu, Yi‐Hua Chen, Kai‐Hsuan Ding, Ho‐Chun Yang, Joakim Lundeberg, Chin‐Min Kimmy Ho, Shu‐Hsing Wu, Mei‐Yeh Jade Lu, Wen‐Hsiung Li   +11 more
wiley   +1 more source