Plant Biotechnology Journal, Volume 24, Issue 5, Page 3141-3157, May 2026.ABSTRACT The ripening of climacteric fruits is characterised by a sharp increase in ethylene production, coinciding with the conversion of starch into soluble sugars. However, the regulatory interplay between ethylene and starch degradation in apple remains largely unclear. Here, we report a negative correlation between starch accumulation and ethylene
Fan Xiao +8 more
wiley +1 more source
Scavenger receptor class B member 1 promotes lung cancer growth and metastasis through enhanced twist family BHLH transcription factor 1 signaling <i>in vitro</i> and <i>in vivo</i>: Exploration of RPPNs as a therapeutic Strategy. [PDF]
CytojournalLiu X, Bian H, Shi Y, Du T.
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The Plant Journal, Volume 126, Issue 3, May 2026.Significance Statement Seed and leaf phenomic traits, including morphology and spectral features, play key roles in consumer preference and plant performance. Here, we conducted a genome‐wide association study of 71 phenomic traits, identifying 73 high‐confidence quantitative trait locus and 114 candidate genes.
Julia von Steimker +14 more
wiley +1 more source
HDAC3 Regulates Transcriptional Networks Governing Decidualization
The FASEB Journal, Volume 40, Issue 8, 30 April 2026.HDAC3 orchestrates transcriptional programs essential for uterine decidualization. Loss of HDAC3 disrupts cytoskeletal organization, metabolic signaling, and oxidative stress responses, impairing stromal cell differentiation and decidualization. These alterations compromise uterine receptivity and result in failed embryo implantation.
Loan Thi Kim Nguyen +5 more
wiley +1 more source
Statement of Retraction: Circular RNA CNOT2 knockdown regulates twist family BHLH transcription factor via targeting microRNA 409-3p to prevent breast cancer invasion, migration and epithelial-mesenchymal transition. [PDF]
Bioengineeredeuropepmc +1 more source
bHLH transcription factors in neural development, disease, and reprogramming
Brain Research, 2019 The formation of functional neural circuits in the vertebrate central nervous system (CNS) requires that appropriate numbers of the correct types of neuronal and glial cells are generated in their proper places and times during development. In the embryonic CNS, multipotent progenitor cells first acquire regional identities, and then undergo precisely ...
Carol Schuurmans
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Liverwort bHLH transcription factors and the origin of stomata in plants
Current Biology, 2023Stomata are distributed in nearly all major groups of land plants, with the only exception being liverworts. Instead of having stomata on sporophytes, many complex thalloid liverworts possess air pores in their gametophytes. At present, whether stomata in land plants are derived from a common origin remains under debate.1,2,3 In Arabidopsis thaliana, a
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Regulation of MYB and bHLH Transcription Factors: A Glance at the Protein Level [PDF]
Molecular Plant, 2015 In complex, constantly changing environments, plants have developed astonishing survival strategies. These elaborated strategies rely on rapid and precise gene regulation mediated by transcription factors (TFs). TFs represent a large fraction of plant genomes and among them, MYBs and basic helix-loop-helix (bHLHs) have unique inherent properties ...
Marie Pireyre, Meike Burow
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The Significance of the Intrinsically Disordered Regions for the Functions of the bHLH Transcription Factors [PDF]
International Journal of Molecular Sciences, 2019 The bHLH proteins are a family of eukaryotic transcription factors regulating expression of a wide range of genes involved in cell differentiation and development. They contain the Helix-Loop-Helix (HLH) domain, preceded by a stretch of basic residues, which are responsible for dimerization and binding to E-box sequences.
Beata Greb-Markiewicz
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