Results 11 to 20 of about 60,389 (159)

Prokineticin 2 Is a Target Gene of Proneural Basic Helix-Loop-Helix Factors for Olfactory Bulb Neurogenesis [PDF]

, 2007
Prokineticin 2, a cysteine-rich secreted protein, regulates diverse biological functions including the neurogenesis of olfactory bulb. Here we show that the PK2 gene is a functional target gene of proneural basic helix-loop-helix (bHLH) factors ...
Anderson, David J., He, Fei, Li, Jia-Da, Ng, Kwan L., Sun, Yi E., Zhang, Chengkang, Zhou, Qun-Yong   +6 more
core   +1 more source

Real-time imaging of bHLH transcription factors reveals their dynamic control in the multipotency and fate choice of neural stem cells [PDF]

, 2015
The basic-helix-loop-helix (bHLH) transcription factors Ascl1/Mash1, Hes1, and Olig2 regulate the fate choice of neurons, astrocytes, and oligodendrocytes, respectively; however, these factors are coexpressed in self-renewing multipotent neural stem ...
Imayoshi, Itaru, Ishidate, Fumiyoshi, Kageyama, Ryoichiro   +2 more
core   +1 more source

Identification of Melatonin-Regulated Genes in the Ovine Pituitary Pars Tuberalis, a Target Site for Seasonal Hormone Control [PDF]

, 2008
The pars tuberalis (PT) of the pituitary gland expresses a high density of melatonin (MEL) receptors and is believed to regulate seasonal physiology by decoding changes in nocturnal melatonin secretion.
Alison Downing, Ando, Andrew S. I. Loudon, Ashburner, Bae, Barrett, Bartness, Bechtold, Benoit Malpaux, Bockers, Bockers, Bockmann, Brahimi-Horn, Camon, Carr, Chemineau, Chen, Curlewis, Daphne Mouzaki, Dardente, Dave W. Burt, David Waddington, Draghici, Dupre, Fukuhara, Gerald A. Lincoln, Ghorbel, Graham, Grossmann, Hanon, Hazlerigg, Hazlerigg, Hazlerigg, Hogenesch, Hu, Hu, Johnston, Johnston, Johnston, Julian R. E. Davis, Kel, Kijas, Klosen, Ko, Lamolet, Lee, Lincoln, Lincoln, Lincoln, Lincoln, Malpaux, Merks, Messager, Michan, Morgan, Morgan, Mutoh, Nakao, Naya, Naya, Nilaweera, Oki, Poulin, Reick, Revollo, Richard Talbot, Roepke, Rutter, Samal, Sandrine M. Dupré, Schroeder, Segawa, Stehle, Stirland, Storey, Su, Tobler, Tournier, Wagner, Westfall, Williams, Wittkowski, Yang, Yokoyama   +83 more
core   +2 more sources

A seed-specific regulator of triterpene saponin biosynthesis in Medicago truncatula [PDF]

, 2020
Plants produce a vast array of defense compounds to protect themselves from pathogen attack or herbivore predation. Saponins are a specific class of defense compounds comprising bioactive glycosides with a steroidal or triterpenoid aglycone backbone. The
Arendt, Philipp, Bicalho, Keylla, Buitink, Julia, Calegario, Gabriela, Ceulemans, Evi, Goossens, Alain, Gryffroy, Lore, Lacchini, Elia, Mertens, Jan, Pollier, Jacob, Ribeiro, Bianca, Vanden Bossche, Robin   +11 more
core   +2 more sources

Elevated expression of human bHLH factor ATOH7 accelerates cell cycle progression of progenitors and enhances production of avian retinal ganglion cells. [PDF]

, 2018
The production of vertebrate retinal projection neurons, retinal ganglion cells (RGCs), is regulated by cell-intrinsic determinants and cell-to-cell signaling events.
Hashimoto, Takao, Tang, Ronald, Yang, Xian-Jie, Zhang, Xiang-Mei   +3 more
core   +1 more source

Generalized, switch-like competitive heterodimerization networks [PDF]

, 2007
High-dimensional switches have been proposed as a way to model cellular differentiation, particularly in the context of basic Helix-Loop-Helix (bHLH) competitive heterodimerization networks.
Cinquin, O, Page, KM
core   +1 more source

Functional Profiling of Transcription Factor Genes in Neurospora crassa. [PDF]

, 2017
Regulation of gene expression by DNA-binding transcription factors is essential for proper control of growth and development in all organisms. In this study, we annotate and characterize growth and developmental phenotypes for transcription factor genes ...
Bekman, Thomas, Blahut, Johnathon, Borkovich, Katherine A, Cabrera, Ilva E, Carrera, Cristian, Carrillo, Alexander J, Chen, Vivian, Clark, Isaiah, Dietrich, Sarah, Fierro, Gerardo, Ganzen, Logan, Mei, Jennifer, Orellana, Jose, Prudhomme, Loren, Schacht, Patrick, Wise, Shelby, Yang, Kevin, Zhong, Hui   +17 more
core   +1 more source

bHLH transcription factors LP1 and LP2 regulate longitudinal cell elongation

Plant Physiology, 2021
Abstract Basic helix–loop–helix/helix–loop–helix (bHLH/HLH) transcription factors play substantial roles in plant cell elongation. In this study, two bHLH/HLH homologous proteins leaf related protein 1 and leaf-related protein 2 (AtLP1 and AtLP2) were identified in Arabidopsis thaliana.
Rui Lu, Jiao Zhang, Yu-Wei Wu, Yao Wang, Jie Zhang, Yong Zheng, Yang Li, Xue-Bao Li   +7 more
openaire   +2 more sources

Role of the bHLH transcription factor TCF21 in development and tumorigenesis [PDF]

Brazilian Journal of Medical and Biological Research, 2021
Transcription factors control, coordinate, and separate the functions of distinct network modules spatially and temporally. In this review, we focus on the transcription factor 21 (TCF21) network, a highly conserved basic-helix-loop-helix (bHLH) protein that functions to integrate signals and modulate gene expression.
C.F.P. Lotfi, B.S. Passaia, J.L. Kremer
openaire   +4 more sources

The bHLH Transcription Factor OsbHLH057 Regulates Iron Homeostasis in Rice

International Journal of Molecular Sciences, 2022
Many basic Helix-Loop-Helix (bHLH) transcription factors precisely regulate the expression of Fe uptake and translocation genes to control iron (Fe) homeostasis, as both Fe deficiency and toxicity impair plant growth and development. In rice, three clade IVc bHLH transcription factors have been characterised as positively regulating Fe-deficiency ...
Wujian Wang, Kamran Iqbal Shinwari, Hao Zhang, Hui Zhang, Lv Dong, Fengyu He, Luqing Zheng   +6 more
openaire   +2 more sources