bHLH transcription factors in neural development, disease, and reprogramming
The formation of functional neural circuits in the vertebrate central nervous system (CNS) requires that appropriate numbers of the correct types of neuronal and glial cells are generated in their proper places and times during development. In the embryonic CNS, multipotent progenitor cells first acquire regional identities, and then undergo precisely ...
Daniel J, Dennis +2 more
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Role and functioning of bHLH transcription factors in jasmonate signalling [PDF]
Plant growth, development and interaction with the environment involve the action of multiple phytohormones. Transcription factors (TFs) of diverse families play essential roles in the signalling cascades triggered by the perception of a particular hormone.
Jonas Goossens +2 more
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Speedy grass stomata: emerging molecular and evolutionary features [PDF]
No abstract ...
Blatt, Michael R. +3 more
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The arabidopsis bHLH transcription factor family
Basic helix-loop-helices (bHLHs) are present in all eukaryotes and form one of the largest families of transcription factors (TFs) found in plants. bHLHs function as transcriptional activators and/or repressors of genes involved in key processes involved in plant growth and development in interaction with the environment (e.g., stomata and root hair ...
Fei Gao, Christian Dubos
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bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana [PDF]
Iron (Fe) deficiency is a limiting factor for the normal growth and development of plants, and many species have evolved sophisticated systems for adaptation to Fe-deficient environments. It is still unclear how plants sense Fe status and coordinate the expression of genes responsive to Fe deficiency.
Liang, Gang +4 more
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Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation [PDF]
Basic helix–loop–helix/Per–Arnt–Sim (bHLH/PAS) transcription factors function broadly in development, homeostasis and stress response. Active bHLH/PAS heterodimers consist of a ubiquitous signal-regulated subunit (e.g., hypoxia-inducible factors, HIF-1α ...
Aitola +52 more
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Redox modulation of plant developmental regulators from the class I TCP transcription factor family [PDF]
TEOSINTE BRANCHED1-CYCLOIDEA-PROLIFERATING CELL FACTOR1 (TCP) transcription factors participate in plant developmental processes associated with cell proliferation and growth.
Gonzalez, Daniel Hector +2 more
core +1 more source
Expression of neurogenin3 reveals an islet cell precursor population in the pancreas [PDF]
Differentiation of early gut endoderm cells into the endocrine cells forming the pancreatic islets of Langerhans depends on a cascade of gene activation events controlled by transcription factors including the basic helix-loop-helix (bHLH) proteins.
Anderson, David J. +8 more
core
Neurogenin3 restricts serotonergic neuron differentiation to the hindbrain [PDF]
The development of the nervous system is critically dependent on the production of functionally diverse neuronal cell types at their correct locations.
Carcagno, Abel Luis +4 more
core +1 more source
MASH1 activates expression of the paired homeodomain transcription factor Phox2a, and couples pan-neuronal and subtype-specific components of autonomic neuronal identity [PDF]
We have investigated the genetic circuitry underlying the determination of neuronal identity, using mammalian peripheral autonomic neurons as a model system.
Anderson, David J. +2 more
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