Results 21 to 30 of about 3,082 (198)

Bovine Herpesvirus 5 (BHV-5) Us9 Is Essential for BHV-5 Neuropathogenesis [PDF]

Journal of Virology, 2002
ABSTRACTBovine herpesvirus 5 (BHV-5) is a neurovirulent alphaherpesvirus that causes fatal encephalitis in calves. In a rabbit model, the virus invades the central nervous system (CNS) anterogradely from the olfactory mucosa following intranasal infection.
Shafiqul I. Chowdhury, Muhittin Önderci, Partha S. Bhattacharjee, Abdullah I. A. Al-Mubarak, Mark L. Weiss, Yi Zhou   +5 more
openalex   +4 more sources

A Glycine-Rich Bovine Herpesvirus 5 (BHV-5) gE-Specific Epitope within the Ectodomain Is Important for BHV-5 Neurovirulence [PDF]

Journal of Virology, 2004
ABSTRACTThe bovine herpesvirus 5 (BHV-5) gE ectodomain contains a glycine-rich epitope coding region (gE5 epitope), residues 204 to 218, that is significantly different from the corresponding gE region of BHV-1. Deletion of the gE epitope significantly reduced the neurovirulence of BHV-5 in rabbits.
Abdullah I. A. Al-Mubarak, You Zhou, Shafiqul I. Chowdhury   +2 more
openalex   +4 more sources

The Us9 Gene of Bovine Herpesvirus 1 (BHV-1) Effectively Complements a Us9-Null Strain of BHV-5 for Anterograde Transport, Neurovirulence, and Neuroinvasiveness in a Rabbit Model [PDF]

Journal of Virology, 2006
ABSTRACTThe alphaherpesvirus envelope protein Us9 is a type II viral membrane protein that is required for anterograde spread of bovine herpesvirus 5 (BHV-5) infection from the olfactory receptor neurons to the brain. In a rabbit seizure model, Us9-deleted BHV-5 failed to invade the central nervous system (CNS) following intranasal infection.
Shafiqul I. Chowdhury, Sharif Mahmood, Jillian N. Simon, Abdullah I. A. Al-Mubarak, Yi Zhou   +4 more
openalex   +3 more sources

Neurological disorder in cattle associated with bovine herpesvirus 4 [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2011
A nested PCR assay was used to diagnose bovine encephalitis through herpesviruses including bovine herpesvirus 5 (BHV-5), bovine herpesvirus 1 (BHV-1), Aujeszky's disease virus (SHV-1), and ovine herpesvirus 2 (OHV-2) in 14 fragments of central nervous ...
E.A. Costa, A.C. Vasconcelos, M.R.Q. Bomfim, H.B. Amorim, G.B.L. Lima, F.M. Coelho, M. Resende   +6 more
doaj   +2 more sources

Diagnosis of Encephalitic Bovine Herpesvirus Type 5 (BHV-5) Infection in Cattle: Virus Isolation and Immunohistochemical Detection of Antigen in Formalin-Fixed Bovine Brain Tissues [PDF]

Journal of Veterinary Diagnostic Investigation, 1995
1. Barry R, Vincent M, Kent S, et al.: 1988, Characterization of prion proteins with monospecific antisera to synthetic peptides. J Immunol 140:1188-1193. 2. Bendheim PE, Barry RA, DeArmond SJ, et al.: 1984, Antibodies to a scrapie prion protein. Nature 310:418-421. 3. Berg LJ: 1994, Insights into the role of the immune system in prion diseases.
Jean M. d’Offay, Ray W. Ely, Charles A. Baldwin, D. L. Whitenack, Ernest L. Stair, James K. Collins   +5 more
openalex   +3 more sources

Antibodies against bovine herpesvirus (BHV) 5 may be differentiated from antibodies against BHV1 in a BHV1 glycoprotein E blocking ELISA

Veterinary Microbiology, 2001
We examined whether antibodies against bovine herpesvirus (BHV) 5 cross-react with BHV1 antigens and whether they could interfere with BHV1 eradication programmes. Six calves were experimentally infected with different doses of BHV5 strain N569; homologous antibodies were first detectable on day 11 post infection; they cross-reacted in a BHV1 virus ...
G.J. Wellenberg, M.H. Mars, J.T. van Oirschot   +2 more
openalex   +4 more sources

Expressão de fatores relacionados à morte celular programada em embriões bovinos infectados com BHV-5

, 2013
É sabido que alguns patógenos podem desencadear o processo de apoptose em determinadas células do organismo, entretanto, o BHV-5 inibe a apoptose em embriões bovinos com sete dias de desenvolvimento. Por esta razão, o objetivo deste trabalho foi investigar a interação vírus-embrião no mecanismo de morte celular programada.
Camila Silva-Frade
openalex   +2 more sources

Molecular basis of antigenic variation between the glycoproteins C of respiratory bovine herpesvirus 1 (BHV-1) and neurovirulent BHV-5

Virology, 1995
Herpesvirus glycoprotein C (gC) functions as a major virus attachment protein. The gC sequence of the neurovirulent bovine herpesvirus type 5 (BHV-5) virus was determined and compared with the gC sequence of the nonneurovirulent BHV-1. Alignment of the predicted amino acid sequences of BHV-1 and BHV-5 gC ORFs showed that the amino-terminal third of the
Shafiqul I. Chowdhury
openalex   +3 more sources

Cyranose^® 320 eNose Effectively Differentiates Pre- and Post-Challenge Respiratory Samples in an Induced Bovine Respiratory Disease Model [PDF]

Veterinary Sciences
Field-based diagnostic technologies which aid in the early detection of bovine respiratory disease (BRD) are of great need, given the rising attention related to animal welfare and antimicrobial stewardship.
Conrad S. Schelkopf, Leslie F. Weaver, Michael D. Apley, Roman M. Pogranichniy, Lance W. Noll, Jianfa Bai, Raghavendra G. Amachawadi, Brian V. Lubbers   +7 more
doaj   +2 more sources

Significant Impact of Schmallenberg Virus in Three Ruminant Farms: A Laboratory Experience. [PDF]

Vet Med Int
Schmallenberg virus (SBV) is endemic in Europe and other parts of the world and represents an underestimated and underdiagnosed cause of abortion and economic losses for livestock farms. In the present study, we evaluated SBV’s impact on three ruminant farms, in particular, two dairy cattle farms with reproductive problems (including abortions ...
Guccione J, Longobardi V, Alterisio MC, Pagnini U, Ferrara G.   +4 more
europepmc   +2 more sources