Results 171 to 180 of about 11,641 (225)

Biased agonism in psychopharmacology: an opportunity to improve efficacy and safety of treatments. [PDF]

CNS Spectr
Le GH, Wong S, Bargiota S, Jennifer S, Lo HKY, Orsini D, Teopiz K, Guillen-Burgos HF, Lim PK, McIntyre RS.   +9 more
europepmc   +1 more source

Legumain Induces Oral Cancer Pain by Biased Agonism of Protease-Activated Receptor-2. [PDF]

J Neurosci, 2021
Tu NH, Jensen DD, Anderson BM, Chen E, Jimenez-Vargas NN, Scheff NN, Inoue K, Tran HD, Dolan JC, Meek TA, Hollenberg MD, Liu CZ, Vanner SJ, Janal MN, Bunnett NW, Edgington-Mitchell LE, Schmidt BL.   +16 more
europepmc   +1 more source

Serotonin 5-HT_2C Receptor Signaling Analysis Reveals Psychedelic Biased Agonism. [PDF]

ACS Chem Neurosci
Bonniwell EM, Alabdali R, Hennessey JJ, McKee JL, Cavalco NG, Lammers JC, Moore EJ, Franchini L, Orlandi C, McCorvy JD.   +9 more
europepmc   +1 more source

Evaluating biased agonism of glucagon-like peptide-1 (GLP-1) receptors to improve cellular bioenergetics: A systematic review. [PDF]

Diabetes Obes Metab
Wong S, Le GH, Dri CE, Teopiz KM, McIntyre RS.   +4 more
europepmc   +1 more source

Biased agonism at free-fatty acid receptor-4 (FFA4/GPR120). [PDF]

Pharmacol Ther
Teyani RL, Moniri NH.
europepmc   +1 more source

Methodical Challenges and a Possible Resolution in the Assessment of Receptor Reserve for Adenosine, an Agonist with Short Half-Life [PDF]

, 2018
Erdei, Tamás Dániel, Gesztelyi, Rudolf, Juhász, Béla, Lampé, Nóra, Papp, Csaba, Pintér, Ákos, Szabó, Katalin, Szentmiklósi, József András, Szilvássy, Zoltán, Zsuga, Judit   +9 more
core   +1 more source

Taming interleukin-12: Engineering of bispecific antibody-based IL-12 mimetics with biased agonism capacities. [PDF]

Protein Sci
Lipinski B, Unmuth L, Arras P, Endruszeit R, Becker S, Rödel JM, Scheller J, Pudewell S, Floss DM, Krah S, Harwardt J, Doerner A, Helming L, Xu C, Menrad A, Evers A, Kolmar H, Elter D, Pekar L, Zielonka S.   +19 more
europepmc   +1 more source

Control of human pancreatic beta cell kinome by GLP-1R biased agonism

, 2023
Xiao J, Eid LE, Buenaventura T, Boutry R, Bonnefond A, Jones B, Rutter GA, Froguel P, Tomas A.   +8 more
europepmc   +1 more source

Allosteric transition: a comparison of two models [PDF]

, 2013

core   +1 more source

Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator. [PDF]

Cell Res
Sun D, Li X, Yuan Q, Wang Y, Shi P, Zhang H, Wang T, Sun W, Ling S, Liu Y, Lai J, Xie W, Yin W, Liu L, Xu HE, Tian C.   +15 more
europepmc   +1 more source