Results 171 to 180 of about 11,411 (182)

Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics

Neuropharmacology, 2020
Daniel Sejer Pedersen, Thor Christian Møller, Dariusz Matosiuk   +2 more
exaly  

Mechanisms of signalling and biased agonism in G protein-coupled receptors

Nature Reviews Molecular Cell Biology, 2018
Denise Wootten, Arthur Christopoulos, Maria Marti-Solano   +2 more
exaly  

Biased Agonism

2008
openaire   +1 more source

The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism

Cell, 2016
Denise Wootten, Christopher A Reynolds, Sebastian George Barton Furness   +2 more
exaly  

Critical Assessment of G Protein-Biased Agonism at the μ-Opioid Receptor

Trends in Pharmacological Sciences, 2020
Alexander Gillis, Andrea Kliewer, Eamonn Kelly   +2 more
exaly  

Biased Agonism at G Protein‐Coupled Receptors: The Promise and the Challenges—A Medicinal Chemistry Perspective

Medicinal Research Reviews, 2014
Jeremy Shonberg, Arthur Christopoulos, Ben Capuano   +2 more
exaly  

Identification of psychedelic new psychoactive substances (NPS) showing biased agonism at the 5-HT2AR through simultaneous use of β-arrestin 2 and miniGαq bioassays

Biochemical Pharmacology, 2020
Eline Pottie, Peter Dedecker, Christophe P Stove   +2 more
exaly  

Biased Agonism as a Mechanism for Differential Signaling by Chemokine Receptors

Journal of Biological Chemistry, 2013
Sudarshan Rajagopal
exaly  

Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors

Annual Review of Pharmacology and Toxicology, 2012
Eric Reiter, Robert J Lefkowitz
exaly  

β-Arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1

Journal of Biological Chemistry, 2015
Kevin Vivot, Michel Bouvier, Vincent Poitout   +2 more
exaly