Results 221 to 225 of about 11,641 (225)

The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism

Cell, 2016
Denise Wootten, Christopher A Reynolds, Cassandra Koole   +2 more
exaly  

Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism

Journal of Biological Chemistry, 2018
Dehua Yang, Yi-Lynn Liang, Cassandra Koole   +2 more
exaly  

Elucidating structural and molecular mechanisms of β-arrestin-biased agonism at GPCRs via MS-based proteomics

Cellular Signalling, 2018
Kunhong Xiao, Jin-Peng Sun
exaly  

Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: Implications for optimizing preclinical neuroscience drug discovery

Neuropharmacology, 2017
Kathy Sengmany, Gregory D Stewart, P Jeffrey Conn   +2 more
exaly  

NOP RECEPTOR TRANSDUCEROME: INSIGHTS INTO BIASED AGONISM

I recettori accoppiati alle proteine G (GPCR) sono la più grande famiglia di recettori espressi sulla superficie cellulare e svolgono ruoli critici in una varietà di attività fisiologiche. I GPCR mediano i loro effetti preferenzialmente attivando le proteine G eterotrimeriche.
openaire   +1 more source