Results 101 to 110 of about 185,950 (192)

Hormonal and Allosteric Regulation of the Luteinizing Hormone/Chorionic Gonadotropin Receptor

Frontiers in Bioscience-Landmark
Luteinizing hormone (LH) and human chorionic gonadotropin (CG), like follicle-stimulating hormone, are the most important regulators of the reproductive system.
Alexander O. Shpakov
doaj   +1 more source

Galanin Receptors: G Protein-Dependent Signaling and Beyond

Biomolecules
The G protein-coupled galanin receptors include three different subtypes: galanin receptor 1, 2 and 3 (GalR1, GalR2, GalR3). The neuropeptide galanin is the principal natural agonist of the galanin receptors, the so-called galaninergic system.
Judit Oláh, Eszter Soltész-Katona, Hana Kaci, Gábor Turu, László Hunyady   +4 more
doaj   +1 more source

Single-Molecule Imaging Reveals Differential AT1R Stoichiometry Change in Biased Signaling. [PDF]

Int J Mol Sci, 2023
Qin G, Xu J, Liang Y, Fang X.
europepmc   +1 more source

Imaging early embryonic calcium activity with GCaMP6s transgenic zebrafish [PDF]

, 2017
Bruchas, Michael R, Chen, Jiakun, Solnica-Krezel, Lilianna, Xia, Li   +3 more
core   +2 more sources

The free fatty acid 2 receptor regulates C5a induced neutrophil superoxide production and its sensitivity to inhibition by the antagonist avacopan

Frontiers in Immunology
IntroductionReceptor transactivation is a novel signaling mechanism used by several different neutrophil G protein-coupled receptors (GPCRs) to activate an allosterically modulated receptor that recognizes short chain free fatty acids.
Zahra Khan, Zahra Khan, Neele K. Levin, Claes Dahlgren, Martina Sundqvist, Fariha Khan, Huamei Forsman, Huamei Forsman, Lena Björkman   +8 more
doaj   +1 more source

G-Protein-Coupled Receptor Kinase 2 Limits CCL21-Induced T Cell Migration via Phospholipase Cγ1

Receptors
Background/Objectives: G protein-coupled receptors (GPCRs) can promote ligand-biased signaling, yet the mechanisms that promote bias are not well understood.
Anahi Sanchez, Caitlin T. Winebrenner, Natalia Garcia, Brian Kaiser, Lyndsey Kilgore, Cesar I. Cardona, Daniel W. Bassuk, Mary E. Miller, Charles A. Bill, Laura A. Shannon, Brant M. Wagener, Amy Wagler, Manuel Llano, Colin A. Bill, Charlotte M. Vines   +14 more
doaj   +1 more source

Molecular mechanism of biased signaling at the kappa opioid receptor. [PDF]

Nat Commun, 2023
El Daibani A, Paggi JM, Kim K, Laloudakis YD, Popov P, Bernhard SM, Krumm BE, Olsen RHJ, Diberto J, Carroll FI, Katritch V, Wünsch B, Dror RO, Che T.   +13 more
europepmc   +1 more source

Mechanism of activation and biased signaling in complement receptor C5aR1. [PDF]

Cell Res, 2023
Feng Y, Zhao C, Deng Y, Wang H, Ma L, Liu S, Tian X, Wang B, Bin Y, Chen P, Yan W, Fu P, Shao Z.   +12 more
europepmc   +1 more source

Divergent Pharmacology and Biased Signaling of the Four Melanocortin-4 Receptor Isoforms in Rainbow Trout (Oncorhynchus mykiss). [PDF]

Biomolecules, 2023
Ji RL, Liu T, Hou ZS, Wen HS, Tao YX.
europepmc   +1 more source

Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases. [PDF]

Int J Mol Sci, 2023
Liu H, Ma H, Zeng X, Wu C, Acharya S, Sudan SK, Zhang X.   +6 more
europepmc   +1 more source