Results 251 to 260 of about 187,893 (285)
Some of the next articles are maybe not open access.
Identification of Frequency of Biased Harmonic Signal
European Journal of Control, 2007zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Stanislav Aranovskiy +4 more
openaire +2 more sources
Biased signaling as allosteric probe dependence
Cellular Signalling, 2021Signaling 'bias' is a phenomenon whereby the natural allosteric probe dependence of seven transmembrane receptors allows different receptor conformations (stabilized by different agonists) to activate some signaling pathways (coupled to pleiotropically coupled receptors) more than others at the expense of those other pathways.
openaire +2 more sources
Emerging structural insights into biased GPCR signaling
Trends in Biochemical Sciences, 2014The discovery of biased signaling at G protein-coupled receptors (GPCRs), the largest class of cell surface receptors and primary drug targets for numerous human diseases, has redefined the classical concepts of receptor pharmacology. It not only highlights the depth of signaling diversity within the GPCR system, but also offers possibilities for novel
Arun K Shukla, Eshan Ghosh
exaly +3 more sources
Biased autoencoder for collaborative filtering with temporal signals
Expert Systems with Applications, 2021Abstract Recommendation systems are used in various types of online platforms and in e-commerce. Collaborative filtering (CF) is one of the most popular approaches for recommendation systems and has been widely studied in academia. In recent years, several models based on neural networks that can discover nonlinear relationships have been proposed ...
Runliang Dou, Oguzhan Arslan, Ce Zhang
openaire +1 more source
GPCR Biased Signaling in Cancer
G protein-coupled receptors (GPCRs) represent the largest family of cell surface receptors. They orchestrate various signaling pathways, playing a central role in regulating various physiological and pathophysiological processes. Dysregulation of GPCR signaling has been intricately linked to cancer pathogenesis, including tumor growth, angiogenesis ...Ariella C, Avigad +10 more
openaire +2 more sources
GPCR Biased Signaling in Metabolism
G protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors and the most prominent drug targets. GPCR-biased signaling exerts different functions through distinct downstream signaling pathways of receptor to maintain body homeostasis.Zhaoyu, Zhang, Zijian, Li
openaire +2 more sources
Probing Biased Signaling in Chemokine Receptors
2016The chemokine system mediates leukocyte migration during homeostatic and inflammatory processes. Traditionally, it is described as redundant and promiscuous, with a single chemokine ligand binding to different receptors and a single receptor having several ligands.
Amarandi, Roxana Maria +3 more
openaire +3 more sources
Biasing GPCR Signaling from Inside
Science Signaling, 2014Strategies that target the intracellular domain of G protein–coupled receptors may enable development of new intracellular biased signaling modulators.
openaire +2 more sources
Signal reconstruction and frequency estimation of a biased and noisy sinusoidal signal
IEEE ICCA 2010, 2010Based on the sampled data of a sinusoidal signal corrupted by unknown constant bias and noise with non-zero mean, a simple and novel approach is proposed to reconstruct the sinusoidal signal having same frequency as the original signal but free from unknown constant bias.
Da Zheng +4 more
openaire +1 more source
Scan BIST with biased scan test signals
Science in China Series F: Information Sciences, 2008The conventional test-per-scan built-in self-test (BIST) scheme needs a number of shift cycles followed by one capture cycle. Fault effects received by the scan flipflops are shifted out while shifting in the next test vector like scan testing. Unlike deterministic testing, it is unnecessary to apply a complete test vector to the scan chains.
Dong Xiang, Mingjing Chen, Jia-Guang Sun
openaire +1 more source