Results 261 to 270 of about 187,893 (285)
Some of the next articles are maybe not open access.
Self-fulfilling currency attacks with biased signals
Journal of Policy Modeling, 2007Abstract S. Morris and H.S. Shin [(1998). Unique equilibrium in a model of self-fulfilling currency attacks. American Economic Review, 88(3), 587–597] have shown in a model of self-fulfilling currency crises that when removing the assumption of common knowledge among speculators multiplicity of equilibria disappears.
DELLA POSTA, POMPEO, CHELI, BRUNO
openaire +2 more sources
GPCR Heterodimers: Implications for Biased Signaling
G protein-coupled receptors (GPCRs) are key mediators of cellular signaling, participating in various physiological and pathological processes. Emerging evidence reveals that GPCRs can form functional heterodimers, wherein two distinct receptor subtypes interact mutually to generate unique signaling complexes.Li, Lin +5 more
openaire +2 more sources
Functional Selectivity and Biased Receptor Signaling
The Journal of Pharmacology and Experimental Therapeutics, 2011With the emergence of information describing functional selectivity and biased agonists and antagonists has come a lack of confidence in "one size fits all" assays for detection of agonism. Seven-transmembrane receptors are pleiotropic with respect to the signaling protein to which they couple in a cell, and many conformations of the receptor can be ...
openaire +2 more sources
GPCR Phospho-Barcodes and Biased Signaling
G protein-coupled receptors (GPCRs), the largest family of membrane receptors in humans, primarily regulate diverse physiological and pathological processes through G protein- and arrestin-mediated signaling pathways, making them important drug targets.Qingtao, He +2 more
openaire +2 more sources
Discussion on:“Identification of Frequency of Biased Harmonic Signal”
European Journal of Control, 2010zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Biased signalling in follicle stimulating hormone action
Molecular and Cellular Endocrinology, 2014Follicle-stimulating hormone (FSH) plays a crucial role in the control of reproduction by specifically binding to and activating a membrane receptor (FSHR) that belongs to the G protein-coupled receptor (GPCR) family. Similar to all GPCRs, FSHR activation mechanisms have generally been viewed as a two-state process connecting a unique FSH-bound active ...
Landomiel, Flavie +8 more
openaire +3 more sources
Biases in signal evolution: learning makes a difference
Trends in Ecology & Evolution, 2007It is now well established that signal receivers have a key role in the evolution of animal communication: the suite of sensory and cognitive processes by which animals perceive and learn about their environment can have a significant impact on signal design.
Carel, ten Cate, Candy, Rowe
openaire +2 more sources
Quantifying Biased β-Arrestin Signaling
2013It is now established that agonists do not uniformly activate pleiotropic signaling mechanisms initiated by receptors but rather can bias signals according to the unique receptor conformations they stabilize. One of the important emerging signaling systems where this can occur is through β-arrestin.
openaire +2 more sources
Histamine H2 Receptor Biased Signaling Methods
2017Fil: Fernandez, Natalia Cristina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Farmacologicas. Universidad de Buenos Aires. Facultad de Farmacia y Bioquimica.
Fernandez, Natalia Cristina +3 more
openaire +2 more sources
Structural Perspectives on Biased Allostery of GPCR Signaling
G protein-coupled receptors (GPCRs) are highly dynamic membrane receptors with numerous subtypes and complex signal transduction pathways. Precise regulation of GPCR signaling is closely related to disease treatment but presents significant challenges with classical orthosteric ligands.Chang, Zhao +5 more
openaire +2 more sources