Results 51 to 60 of about 289,968 (296)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Cigarette Smoke Extract Produces Superoxide in Aqueous Media by Reacting with Bicarbonate

open access: yesToxics, 2021
The toxicity of cigarette smoke (CS) is largely attributed to its ability to generate reactive oxygen species (ROS). Reportedly, CS generates superoxide in cell culture systems by stimulating the cells to produce superoxide and through direct chemical ...
Jung-Min Park   +8 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials

open access: yesAdvanced Engineering Materials, EarlyView.
Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley   +1 more source

Tripodal transmembrane transporters for bicarbonate [PDF]

open access: yes, 2010
Easy-to-make tripodal tris-thiourea receptors based upon tris(2-aminoethyl)amine are capable of chloride/bicarbonate transport and as such represent a new class of bicarbonate transport agent.
Jeffery T. Davis   +15 more
core   +1 more source

Using the Response Surface Methodology to Treat Tannery Wastewater with the Bicarbonate-Peroxide System

open access: yes, 2023
A bicarbonate-peroxide (BAP) system was evaluated to improve the quality of industrial tannery wastewater using an I-optimal experimental design with four variables (temperature, initial pH, bicarbonate, and H2O2 concentration).
Néstor A. Urbina-Suarez   +11 more
core   +1 more source

Inorganic carbon acquisition in Palmaria palmata (Rhodophyta) [PDF]

open access: yes, 2010
PhDDIC acquisition mechanisms and the use of DIC in photosynthesis were examined in the temperate red macroalga, Palmaria palmata (Linnaeus) O. Kuntze.
Hill, Gregg
core   +2 more sources

On the substrate turnover rate of NBCe1 and AE1 SLC4 transporters: structure-function considerations

open access: yesFrontiers in Physiology
A transport protein’s turnover rate (TOR) is the maximum rate of substrate translocation under saturating conditions. This parameter represents the number of transporting events per transporter molecule (assuming a single transport site) per second (s ...
Alexander Pushkin   +8 more
doaj   +1 more source

Electrodeposition in Structural Lattices of Variable Architectures

open access: yesAdvanced Engineering Materials, EarlyView.
Electrodeposition enables geometry‐sensitive, autonomous void filling while simultaneously tuning chemical and mechanical properties. The development of approaches that can autonomously fill and heal material voids and yield composites with tailorable properties is increasingly relevant in engineering.
Yeong‐Man Kwon   +3 more
wiley   +1 more source

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