Results 71 to 80 of about 523,087 (393)
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Serum Bicarbonate Deficiency in Dogs with Acute and Chronic Kidney Disease
Veterinary Sciences, 2023 Serum bicarbonate deficiency is a disorder frequently found in human patients with acute (AKI) and chronic (CKD) kidney disease, due to abnormalities in kidney generation and reabsorption of bicarbonate.
Ilaria Lippi +5 more
doaj +1 more source
Influence of bicarbonate on parathyroid hormone-induced changes in fluid absorption by the proximal tubule [PDF]
, 1976 Influence of bicarbonate on parathyroid hormone-induced changes in fluid absorption by the proximal tubule. Segments of the proximal tubule of the rabbit kidney were perfused in vitro in order to examine the influence of bicarbonate on the reduction in ...
Dennis, Vincent W.
core +1 more source
Nature Microbiology, 2019 A newly discovered energy-linked carbonic anhydrase, DabBA2, is a two-protein complex responsible for inorganic carbon accumulation in the sulfur bacterium Halothiobacillus neapolitanus. DABs are present in a wide range of proteobacterial clades, suggesting that they function in diverse metabolic pathways.
Price, Dean +2 more
openaire +4 more sources
Randomized, Controlled Trial of TRC101 to Increase Serum Bicarbonate in Patients with CKD.
American Society of Nephrology. Clinical Journal, 2018 BACKGROUND AND OBJECTIVES Metabolic acidosis is common in patients with CKD and has significant adverse effects on kidney, muscle, and bone. We tested the efficacy and safety of TRC101, a novel, sodium-free, nonabsorbed hydrochloric acid binder, to ...
D. Bushinsky +11 more
semanticscholar +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
Point-of-Care Testing to Differentiate Various Acid–Base Disorders in Chronic Kidney Disease
Diagnostics, 2023 Background: Normal-anion-gap metabolic acidosis (AGMA) and high-anion-gap metabolic acidosis (HAGMA) are two forms of metabolic acidosis, which is a common complication in patients with chronic kidney disease (CKD).
Tomasz Gołębiowski +12 more
doaj +1 more source
Nitrate And Bicarbonate Selective Chemfets [PDF]
, 1995 The development of durable anion selective CHEMFET micro sensors is described. Selectivity in these sensors is either obtained from differences in hydration energy of the anions (the Hlofmeister series, giving nitrate selectivity) or by introduction of a
Antonisse, Martijn M.G. +2 more
core +1 more source
Smart worm-like micelles responsive to CO₂/N₂ and light dual stimuli [PDF]
, 2017 CO₂/N₂ and light dual stimuli-reponsive worm-like micelles (WLMs) were obtained by addition of a relatively small amount of a switchable surfactant, 4-butyl-4´-(4-N,N-dimethylhexyloxy-amine) azobenzene bicarbonate (AZO-B6-CO₂), sensitive to the same ...
Binks, Bernard P. +4 more
core +1 more source
Journal of Thoracic Disease, 2018 Background Sodium bicarbonate administration during cardiopulmonary resuscitation (CPR) is controversial. Current guidelines recommend sodium bicarbonate injection in patients with existing metabolic acidosis, but clinical trials, particularly, those ...
Shin Ahn +6 more
semanticscholar +1 more source