Results 71 to 80 of about 56,899 (289)

Biological niches within human calcified aortic valves. Towards understanding of the pathological biomineralization process [PDF]

open access: yes, 2015
Despite recent advances, mineralization site, its microarchitecture, and composition in calcific heart valve remain poorly understood. A multiscale investigation, using scanning electron microscopy (SEM), transmission electron microscopy (TEM), and ...
Cavarretta, Elena   +6 more
core   +3 more sources

Evolving treatment options for valve and aortic disease with bicuspid aortic valve [PDF]

open access: yesAnnals of Translational Medicine, 2017
Treatment decisions for patients with bicuspid aortic valves (BAVs) are unique for two principal reasons: (I) aortopathy with dilation of the proximal aorta is seen about 50% of cases, and frequently requires a combined repair; (II) patients are significantly younger than those undergoing treatment for acquired aortic valve disease, making the ...
Michael D. Hope, Nicholas S. Burris
openaire   +3 more sources

Establishment and characterization of human induced pluripotent stem cell line (WMUi020-A) from a patient with bicuspid aortic valve aortopathy

open access: yesStem Cell Research, 2021
A human induced pluripotent stem cell (hiPSC) line (WMUi020-A) was generated from the aortic smooth muscle cells of a 56-year-old donor with bicuspid aortic valve and ascending aortic aneurysm.
Li Dong   +9 more
doaj   +1 more source

Evolution of Precision Medicine and Surgical Strategies for Bicuspid Aortic Valve-Associated Aortopathy

open access: yesFrontiers in Physiology, 2017
Bicuspid aortic valve (BAV) is a common congenital cardiac malformation affecting 1–2% of people. BAV results from fusion of two adjacent aortic valve cusps, and is associated with dilatation of the aorta, known as bicuspid valve associated aortopathy ...
Ali Fatehi Hassanabad   +8 more
doaj   +1 more source

Effect Of Coronary Bypass And Valve Structure On Outcome In Isolated Valve Replacement For Aortic Stenosis [PDF]

open access: yes, 2012
Reports differ regarding the effect of concomitant coronary artery bypass grafting (CABG) in patients who undergo aortic valve replacement (AVR) for aortic stenosis (AS), and no reports have described the effect of aortic valve structure in patients who ...
Filardo, Giovanni   +8 more
core   +1 more source

Bicuspid Aortic Valve: a Review with Recommendations for Genetic Counseling [PDF]

open access: yes, 2016
Bicuspid aortic valve (BAV) is the most common congenital heart defect and falls in the spectrum of left-sided heart defects, also known as left ventricular outflow tract obstructive (LVOTO) defects.
Freeze, Samantha L.   +3 more
core   +1 more source

Proximal aortic stiffening in Turner patients may be present before dilation can be detected : a segmental functional MRI study [PDF]

open access: yes, 2017
Background: To study segmental structural and functional aortic properties in Turner syndrome (TS) patients. Aortic abnormalities contribute to increased morbidity and mortality of women with Turner syndrome.
Achten, Eric   +10 more
core   +2 more sources

Role of Echocardiography Before Transcatheter Aortic Valve Implantation (TAVI) [PDF]

open access: yes, 2016
Aortic stenosis (AS) is the most common primary valve disorder in the elderly with an increasing prevalence; transcatheter aortic valve implantation (TAVI) has become an accepted alternative to surgical aortic valve replacement (AVR) in the high risk or ...
Badiani, S, Bhattacharyya, S, Lloyd, G
core   +1 more source

SMAD3 contributes to ascending aortic dilatation independent of transforming growth factor-beta in bicuspid and unicuspid aortic valve disease

open access: yesScientific Reports, 2022
We sought to determine whether there are differences in transforming growth factor-beta (TGFß) signaling in aneurysms associated with bicuspid (BAV) and unicuspid (UAV) aortic valves versus normal aortic valves.
B. Balint   +5 more
semanticscholar   +1 more source

Aortic valve and aortic arch pathology after coarctation repair [PDF]

open access: yes, 2003
OBJECTIVE: To investigate the incidence of clinical problems related to a bicuspid valve (aortic stenosis and regurgitation) and the incidence of ascending aorta and aortic arch pathology in combination with coarctation repair.
Boersma, H. (Eric)   +7 more
core   +1 more source

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