Results 71 to 80 of about 2,761 (194)

Effects of specific inhibitors on biflavonoid-induced migration of KUM6 cells.

, 2015
(A) Procyanidin A2, (B) procyanidin B1, and (C) morelloflavone. Inhibitors were used at 25 μM, 50 nM, 1 μM, 25 μM, and 100 μM for LY294002, Gö6983, U-73343, nordihydroguaiaretic acid, and azathioprine, respectively.
Katsunori Kuge (836430), Shunya Sahara (836432), Koichi Nakaoji (836434), Kazuhiko Hamada (836435), Katsuto Tamai (365004), Kosuke Fujita (836429), Yukiko Takenaka (836436), Takao Tanahashi (504831), Yasufumi Kaneda (80818), Akito Maeda (836437), Noriyasu Ozawa (836431), Kaori Zaiki (836433)   +11 more
core   +1 more source

A Novel Biflavonoid from

Natural Product Communications, 2016
An investigation of the leaves of Rhus leptodictya led to the isolation of the new biflavonoid: 5,5″,6″,7,8-pentahydroxy-2,2″-bis( p -hydroxyphenyl)-4 H ,4″ H 3,7″-bichromene-4,4″-dione the structure of which was established by NMR spectroscopy and mass ...
Tshifhiwa Matamela, Ivan R. Green, Fanyana M. Mtunzi   +2 more
doaj   +1 more source

Nanoenabled Phytochemical Mining: Gold Nanoparticle‐Mediated Recovery of Low‐Polar Secondary Metabolites From Plant Extract

Small Structures, Volume 7, Issue 3, March 2026.
Green‐synthesized gold nanoparticles serve as tunable nanoadsorbents for selectively enriching low‐polarity secondary metabolites from Hypericum perforatum extracts. Structure‐ and polarity‐dependent interactions, optimized by solvent composition and incubation time, enable efficient recovery of phloroglucinols and xanthones for phytochemical ...
Matam Pradeep, Suman Kalyan Sahoo, Dibyendu Mondal, Gregory Franklin   +3 more
wiley   +1 more source

The biflavonoid amentoflavone inhibits neovascularization preventing the activity of proangiogenic vascular endothelial growth factors

, 2011
The proangiogenic members of VEGF family and related receptors play a central role in the modulation of pathological angiogenesis. Recent insights indicate that, due to the strict biochemical and functional relationship between VEGFs and related ...
Lund Frank Walter, Lepore Laura, Augusto Orlandi, Pisano, Claudio, De Falco, S, Pisano Claudio, Dal Piaz, F, Roepstorff Peter, Ponticelli, Salvatore, Tudisco Luisa, De Falco Sandro, Salvatore Ponticelli, Nunziatina De Tommasi, Frederik Wendelboe Lund, De Falco, Sandro, Ponticelli Salvatore, Pisano, C, Fabrizio Dal Piaz, Roepstorff, Peter, Marcellini, M, Tudisco, L, Roepstorff, P, Sandro De Falco, Tudisco, Laura, DAL PIAZ, FABRIZIO, Tarallo Valeria, Laura Lepore, Laura Tudisco, Peter Roepstorff, Tarallo, Valeria, De Tommasi, N, Lepore, Laura, Lepore, L, ORLANDI, AUGUSTO, Lund, F, Claudio Pisano, De Falco, S., Ponticelli, S, Tarallo, V, Valeria Tarallo, DE TOMMASI, Nunziatina, Orlandi, A, Marcella Marcellini, Marcellini, Marcella, Marcellini Maria, Lund, Frederik Wendelboe, Orlandi Augusto   +46 more
core   +1 more source

A NEW BIFLAVONOID FROM LONICERA SEMPERVIRENS

Zagazig Journal of Pharmaceutical Sciences, 2005
Phytochemical investigation of both the chloroform and ethyl acetate extracts of Lonicera sempervirens led to the isolation of seven compounds identified as betulin 1, a new flavonoid compound named (lonisemperin) scutellarein-(6-O-3')-acacetin 2 ...
Mona Zaghloul
doaj   +1 more source

Design, Synthesis, and Evaluation of Bis‐Chalcones and Bis‐Flavones as Selective COX‐2 Inhibitors

Chemical Biology &Drug Design, Volume 107, Issue 3, March 2026.
Novel bis‐chalcones were successfully synthesized and demonstrated COX‐2 selective inhibition and the ability to inhibit PGE2 production in whole human blood. Notably, a monomeric chalcone with a similar substitution pattern exhibited even greater activity, providing valuable insights to guide the future design and optimization of flavonoid‐based COX‐2
Rui Pereira, Marisa Freitas, Alberto N. Araújo, Vera L. M. Silva, Eduarda Fernandes   +4 more
wiley   +1 more source

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy, Sivaraman Arumugam, Robin Charles Antony Arulraj, Anne Wincy Jacob Thomas, Henrique D. M. Coutinho   +4 more
wiley   +1 more source

Cytotoxic activity and molecular docking of a novel biflavonoid isolated from Jacaranda acutifolia (Bignoniaceae)

, 2015
A novel biflavonoid [kaempferol (6→8″) apigenin] was isolated from the leaves of Jacaranda acutifolia. The structure was elucidated based on chemical evidence, 1D and 2D spectroscopic analyses as well as spectrometric techniques.
Nada M. Mostafa (829252), Omayma A. Eldahshan (829254), Abdel Nasser B. Singab (613621), Mohamed L. Ashour (829253)   +3 more
core   +1 more source

Characterisation of the biflavonoid hinokiflavone as a pre-mRNA splicing modulator that inhibits SENP [PDF]

, 2017
We have identified the plant biflavonoid hinokiflavone as an inhibitor of splicing in vitro and modulator of alternative splicing in cells. Chemical synthesis confirms hinokiflavone is the active molecule.
Richard Hartley, Lewis J King, Triin Tammsalu, Hay, Ronald T, Hartley, Richard C, Ursula Ryder, Pawellek, Andrea, Helmi Kreinin, Andrea Pawellek, Ronald T Hay, Tony Ly, Lamond, Angus; id_orcid, Kreinin, Helmi, Lamond, Angus I., Hay, Ronald T., Lamond, Angus I, Tammsalu, Triin, Ryder, Ursula, Ly, Tony, King, Lewis J, Ronald T. Hay, Angus I. Lamond, Angus I Lamond, Richard C Hartley, Hartley, Richard, Lewis J. King, King, Lewis J.   +26 more
core   +1 more source

A Review on Ginkgo biloba: Nutritional Profile, Toxicity, and Its Therapeutic Potential in Stroke Management

eFood, Volume 7, Issue 1, February 2026.
Stroke is a neurological impairment caused by vascular injury of the central nervous system, and globally, stroke is ranked as the second most common cause of death and disability. Numerous risk factors, disease processes, and mechanisms can contribute to stroke, which is not a single disease. G.
Ali Ikram, Farhang Hameed Awlqadr, Hamna Tayyab, Mamoona Shehzadi, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Ahmadullah Zahir   +6 more
wiley   +1 more source