Using metrics and sustainability considerations to evaluate the use of bio-based and non-renewable Brønsted acidic ionic liquids to catalyse Fischer esterification reactions [PDF]
, 2013 Background Ionic liquids have found uses in many applications, one of which is the joint solvation and catalysis of chemical transformations. Suitable Brønsted acidic ionic liquids can be formed by combining lactams with sulphonic acids. This work weighs
AC Cole +51 more
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Biginelli multicomponent reactions
, 2015 Biginelli reaction is one of the most remarkable examples of MCRs discovered in 1893 and proof of its importance is the high number of articles reported in the last decade covering this field. This strategy allows the synthesis of important building blocks and versatile synthons such as 3,4-dihydropyrimidin-2-(1H)-one derivatives (DHPMs), which are ...
Marqués-López, Eugenia +1 more
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An unexpected Ireland–Claisen rearrangement cascade during the synthesis of the tricyclic core of Curcusone C: Mechanistic elucidation by trial-and-error and automatic artificial force-induced reaction (AFIR) computations [PDF]
, 2019 In the course of a total synthesis effort directed toward the natural product curcusone C, the Stoltz group discovered an unexpected thermal rearrangement of a divinylcyclopropane to the product of a formal Cope/1,3-sigmatropic shift sequence.
Houk, K. N. +6 more
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E-Journal of Chemistry, 2011 Trifluoroacetic acid (TFA) is introduced as an effective catalyst for promotion of Biginelli reaction. 3,4-Dihydropyrimidin-2(1H)-one (-thione) derivatives (DHPMs) were simply and efficiently prepared using TFA catalyzed one-pot, three-component ...
Mohammad R. Mohammadizadeh, Neda Firoozi
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Molbank, 2017 A new compound belonging to the “heterostilbene” derivative, namely ethyl (E)-4-(2,4-dimethoxyphenyl)-6-(2,4-dimethoxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (2), has been successfully synthesized as an unprecedented side product of the ...
Hery Suwito +6 more
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Advances in Biginelli reaction: A comprehensive review [PDF]
, 2023 Aravind Chandravarkar +2 more
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Biginelli Reaction Mediated Synthesis of Antimicrobial Pyrimidine Derivatives and Their Therapeutic Properties. [PDF]
Molecules, 2021 Marinescu M.
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Application of Deep Eutectic Solvents in Promiscuous Lipase-Catalysed Aldol Reactions [PDF]
, 2016 Financial support to this work was provided by the Spanish Ministerio de Economía y Competitividad (MEC) (CTQ2013-44153-P) and the Gobierno del Principado de Asturias (FC-15- GRUPIN14-002).
González Martínez, Daniel +2 more
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Development of chiral phosphoric acids based on ferrocene-bridged paracyclophane frameworks [PDF]
, 2013 International audienceThis work deals with the development of a new family of planar chiral phosphoric acids, based on a ferrocenophane/paracyclophane scaffold.
Betzer, Jean-François +7 more
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A four-component modified Biginelli reaction: A novel approach for C-2 functionalized dihydropyrimidines. [PDF]
Turk J Chem, 2021 Narkhede H, Dhake A, Balasubramaniyan V.
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