Results 101 to 110 of about 2,041,750 (198)

Ex vivo evaluation of the effect of dihydropyrimidine derivatives on serum NGAL levels in women with urinary tract infections: a comparative study with healthy women

Bulletin of Pharmaceutical Sciences. Assiut University
The results showed that the (NGAL) in female patients increased to (230.52 ± 42.25 pg/mL) compared to healthy patients, which was (188.01 ± 33.20 pg/mL), with a statistically significant difference at a probability level of P ≤ 0.05. A ROC curve analysis
Mohammed Mahal, Osama Ibrahim
doaj   +1 more source

P(HEMA)-SO₃H catalyzed Biginelli reaction

Dihidropirimidinonlar (DHPM)'ler farmasötik ve medikal kimyada çok önemli bileşiklerdir. Dihidropirimidinonların sentezi için en yaygın kullanılan yöntem, Biginelli reaksiyonu olarak bilinen, etil asetoasetat, aril aldehit ve üre (veya tiyoüre)’ nin ...
Berthe, Mamadou Lamine
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Highly Enantioselective Biginelli Reaction of Aliphatic Aldehydes Catalyzed by Chiral Phosphoric Acids

, 2017
Several chiral phosphoric acids were evaluated as organocatalysts for the enantioselective Biginelli reaction of aliphatic aldehydes. With a chiral phosphoric acid derived from 3,3′-bis(3,5-di-tert-butyl-4-methoxyphenyl)-1,1′-binaphthalene-2,2′-diol, and
Zhenhua Gao, Hui Zhong, Yongbiao Guo, Chuanpin Zou, Huilan Yu, Xiangyan Meng, Guilan Huang, Xiaoqin Ding, Hui Tang   +8 more
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Design, synthesis and biological Evaluation of novel chromones having 3,4-dihydropyrimidin-2(1H)-one core at C-8 in combination with triazoles: New α-glucosidase inhibitors and anti-bacterial agents

European Journal of Medicinal Chemistry Reports
The Biginelli reaction synthesizes dihydropyrimidones through a multi-component reaction. A β-ketoester, aldehyde, and urea or thiourea react in the presence of an acid catalyst to form these dihydropyrimidones.
Kumara Swamy Taviti, T.B. Patrudu, Nagalakshmi Jeedimalla, Naresh Kumar Katari, Satyanarayana Yatam, Rambabu Gundla   +5 more
doaj   +1 more source

An Environmentally Friendly Solvent-free Synthesis of 3,4-Dihydropyrimidinones using a p-Aminobenzene Sulfonic Acid Catalyzed Biginelli Reaction [PDF]

, 2015
Anhydrous p-aminobenzene sulphonic acid mediated solvent-free protocol is described for the synthesis of dihydropyrimidinones by the cyclocondensation of aldehydes, β-ketoesters and urea/thiourea.
Wu, MS, Zhang, XZ, He, P
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Biginelli reaction catalyzed by ‘Ionic liquid- ethylene glycol’ protected copper nanoparticles at room temperature^a.

, 2012
Biginelli reaction catalyzed by ‘Ionic liquid- ethylene glycol’ protected copper nanoparticles at room temperaturea.
Subho Mozumdar (141584), Amit Saxena (76487), Ajeet Kumar (141578), Arnab De (141581), Manika Dewan (141577)   +4 more
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Synthesis Of Modified Biginelli Compounds

, 2018
The Biginelli reaction has been a distinguished reaction for many years. Their products, the Dihydropyrimidones have been shown to contain a vast array of bioactivity especially when they contain other known bioactive functional groups.
Collins, Michelle Sarah
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Biginelli Reaction: Compilation of Eco-Friendly Approaches for Synthesis of Functionalized 3,4-dihydro-2(H) pyrimidinone (DHPMs)

: The Biginelli reaction is a multicomponent chemical reaction that synthesises 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) from a β-keto ester, an aryl aldehyde, and urea, as described by Pietro Biginelli in 1891.
Priyanka Sharma, Sourav Handique
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Cobalt Ferrite Nanoparticles: Highly Efficient Catalysts for the Biginelli Reaction

This study introduces an efficient and sustainable catalytic system utilizing cobalt ferrite nanoparticles (CoFe2O4-NPs) for the synthesis of valuable 6-amino-2-oxo-4-phenyl (or 4-chlorophenyl)-1,2,3,4-tetrahydropyrimidine-5-carbonitrile derivatives ...
Emad M. El-Telbani, Imam Saheb Syed, Waleed M. Alamier, Ayyob M. Bakry   +3 more
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Iron(II) triflate catalyzed synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones via the Biginelli reaction

Dihydropyrimidinones and dihydropyrimidine thiones are biologically active compounds that have been of interest in the medicinal field. The most common synthetic route to these molecules is the Biginelli reaction, which involves a multicomponent ...
Lyth, Kyle A., David, Rem Quintin V.
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