A four-component modified Biginelli reaction: A novel approach for C-2 functionalized dihydropyrimidines. [PDF]
Narkhede H, Dhake A, Balasubramaniyan V.
europepmc +1 more source
Efficient and Green Microwave-Assisted Multicomponent Biginelli Reaction for the Synthesis of Dihydropyrimidinones Catalyzed by Heteropolyanion-Based Ionic Liquids Under Solvent-Free Conditions [PDF]
An efficient and green route for the synthesis of dihydropyrimidinones via microwave-assisted Biginelli reaction catalyzed by 3 mol% of heteropolyanion-based ionic liquids under solvent-free conditions has been reported.
Zhikai Chen (651674) +8 more
core +1 more source
Methyl 6-Methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate
Methyl 6-methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate has been synthesized via Biginelli reaction of 4-iodobenzaldehyde, methyl acetoacetate and thiourea, promoted by microwave irradiation in the presence of iodine under ...
Qingjian Liu, Ning Pan, Wenwen Zhang
doaj +1 more source
A Brønsted acidic ionic liquid anchored to magnetite nanoparticles as a novel recoverable heterogeneous catalyst for the Biginelli reaction. [PDF]
Oboudatian HS, Naeimi H, Moradian M.
europepmc +1 more source
Tungsten-substituted molybdophosphoric acid impregnated with kaolin: effective catalysts for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones via biginelli reaction. [PDF]
Aher DS +3 more
europepmc +1 more source
Synthesis Of Modified Biginelli Compounds [PDF]
The Biginelli reaction has been a distinguished reaction for many years. Their products, the Dihydropyrimidones have been shown to contain a vast array of bioactivity especially when they contain other known bioactive functional groups.
Collins, Michelle Sarah
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Cobalt Ferrite Nanoparticles: Highly Efficient Catalysts for the Biginelli Reaction [PDF]
This study introduces an efficient and sustainable catalytic system utilizing cobalt ferrite nanoparticles (CoFe2O4-NPs) for the synthesis of valuable 6-amino-2-oxo-4-phenyl (or 4-chlorophenyl)-1,2,3,4-tetrahydropyrimidine-5-carbonitrile derivatives ...
Emad M. El-Telbani +3 more
core +1 more source
An Environmentally Friendly Solvent-free Synthesis of 3,4-Dihydropyrimidinones using a p-Aminobenzene Sulfonic Acid Catalyzed Biginelli Reaction [PDF]
Anhydrous p-aminobenzene sulphonic acid mediated solvent-free protocol is described for the synthesis of dihydropyrimidinones by the cyclocondensation of aldehydes, β-ketoesters and urea/thiourea.
Wu, MS, Zhang, XZ, He, P
core +1 more source
The Biginelli reaction synthesizes dihydropyrimidones through a multi-component reaction. A β-ketoester, aldehyde, and urea or thiourea react in the presence of an acid catalyst to form these dihydropyrimidones.
Kumara Swamy Taviti +5 more
doaj +1 more source
Iron(II) triflate catalyzed synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones via the Biginelli reaction [PDF]
Dihydropyrimidinones and dihydropyrimidine thiones are biologically active compounds that have been of interest in the medicinal field. The most common synthetic route to these molecules is the Biginelli reaction, which involves a multicomponent ...
Lyth, Kyle A., David, Rem Quintin V.
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