Results 81 to 90 of about 2,041,750 (198)

Sustainable Biginelli chemistry: Indian contributions to green multicomponent synthesis

Discover Chemistry
The Biginelli Reaction is a one-pot acid-catalysed cyclo-condensation procedure that combines urea, β-ketoester, and aromatic aldehydes to create functionalised DHPMs. For more than a century, this three-component reaction has been recognised as a method
Rajni, Sahil, Neera Raghav, Anjaneyulu Bendi, G. B. Dharma Rao   +4 more
doaj   +1 more source

Synthesis of bioactive heterocycles using reusable heterogeneous catalyst HClO4–SiO2 under solvent-free conditions

Green Chemistry Letters and Reviews, 2018
We are reporting a simple, efficient and green protocol for the synthesis of chromenes and dihydropyrimidines (products of Knoevenagel and Biginelli reaction, respectively) by the use of silica-supported perchloric acid (HClO4–SiO2) as an effective ...
Leimajam Vartima Chanu, Thokchom Prasanta Singh, Laishram Ronibala Devi, Okram Mukherjee Singh   +3 more
doaj   +1 more source

Highly Efficient Synthesis of Substituted 3,4-Dihydropyrimidin-2-(1H)-ones (DHPMs) Catalyzed by Hf(OTf)₄: Mechanistic Insights into Reaction Pathways under Metal Lewis Acid Catalysis and Solvent-Free Conditions

Molecules, 2019
In our studies on the catalytic activity of Group IVB transition metal Lewis acids, Hf(OTf)4 was identified as a highly potent catalyst for „one-pot, three-component„ Biginelli reaction.
Rui Kong, Shuai-Bo Han, Jing-Ying Wei, Xiao-Chong Peng, Zhen-Biao Xie, Shan-Shan Gong, Qi Sun   +6 more
doaj   +1 more source

Solvent free one pot synthesis of novel naphtho[1,8-gh] quinazoline-7,10-dione derivatives with CuCl2

Bulletin of the Chemical Society of Ethiopia, 2018
The Biginelli-type reaction of phenalen-1,3-dione with urea, and benzaldehyde derivatives in the presence of CuCl2 as a catalyst for the synthesis of naphtho[1,8-gh]quinazoline-7,10-diones in solvent free condition are reviewed.
M. K. Mohammadi
doaj   +1 more source

Methyl 6-Methyl-1-(4-methylphenyl)-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Molbank, 2012
Methyl 6-methyl-1-(4-methylphenyl)-2-oxo-4-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylate has been synthesized via the modified Biginelli reaction from benzaldehyde, p-tolylurea, and methyl acetoacetate, promoted with microwave irradiation and ...
Haiping Wang, Qing Chen, Qingjian Liu
doaj   +1 more source

Lanthanide Triflate Catalyzed Biginelli Reaction. One-Pot Synthesis of Dihydropyrimidinones under Solvent-Free Conditions

, 2016
Lanthanide Triflate Catalyzed Biginelli Reaction.
Limin Wang (87511), Min Yang (146229), Yun Ma (119475), Changtao Qian (2641480)   +3 more
core   +1 more source

Green and Efficient Synthesis of Dihydropyrimidinone Analogues via Hpa-Clay Catalyzed Biginelli Reaction

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry
This study introduces an environmentally sustainable approach for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs), via the Biginelli reaction. A heterogeneous catalyst, Heteropolyacid-Clay (HPA-Clay), is developed by immobilizing H5PV2W10O40 on ...
Nuzhat Rehman, Ayaz Mahmood Dar, Raja Feroz Ahmad Haji, Sharief-ud-din Khan, Deepak Pareek, Saleem Farooq, Bashir Ahmad Dar   +6 more
doaj   +1 more source

Ethyl (E)-4-(2,4-Dimethoxyphenyl)-6-(2,4-dimethoxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Molbank, 2017
A new compound belonging to the “heterostilbene” derivative, namely ethyl (E)-4-(2,4-dimethoxyphenyl)-6-(2,4-dimethoxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (2), has been successfully synthesized as an unprecedented side product of the ...
Hery Suwito, Lutfan Zulianto, Kautsar Ul Haq, Erwanto Erwanto, Abdulloh Abdulloh, Alfinda Novi Kristanti, Indriani Indriani   +6 more
doaj   +1 more source

Pivalic acid assisted Biginelli reaction for synthesis of dihydropyrimidinones and dihydrothiopyrimidinones [PDF]

, 2020
677-681Herein is provided an alternate, simple, multigram scale, efficient route for Biginelli reaction for synthesis of dihydropyrimidinones using urea, ethylacetatoacetate, and benzaldehyde with pivalic ...
Mhaldar, Shashank N, Chodankar, Anika Arjun, Gawas, Anushri Laxman, Anvekar, Tushar S, Salgaonkar, Lalitprabha N, Vernekar, Shruti Sagun, Vaz, Teotone, Kadam, Hari K, Gaonkar, Saurabh Sudan   +8 more
core  

Unprecedented linear products by a mechanochemically activated Biginelli reaction using lawsone

International audienceThe Biginelli reaction, a crucial multicomponent reaction, was investigated involving 2-hydroxy-1,4-naphthoquinone (lawsone), p-substituted benzaldehydes, and ureas. Surprisingly, the classic Biginelli cyclized DHPM was not observed
Carbonnière, Philippe, Vendier, Laure, Bijani, Christian, Robert, Anne, Baltas, Michel, Sotiropoulos, Jean-Marc, Koumpoura, Christina, L   +6 more
core   +1 more source