Results 81 to 90 of about 3,427 (216)
An Improved Protocol for Biginelli Reaction
Green and Sustainable Chemistry, 2013 [Hmim][Tfa] was used as catalyst for the Biginelli reaction under microwave heating. Low catalyst loading, reduced reaction time and operational simplicity are the main highlights of this protocol. The proposed protocol was found active in the synthesis of 30 different biologically active compounds.
openaire +2 more sources
A modular, one-pot, four-component synthesis of polysubstituted 1,3-oxazolidines [PDF]
, 2005 4 pages, 1 figure, 1 table, 1 scheme.-- PMID: 15675866 [PubMed].-- Printed version published Feb 4, 2005.Supporting information available: Spectroscopic and analytical data for compounds 3c-j.-- Available at: http://pubs.acs.org/doi/suppl/10.1021 ...
García-Tellado, Fernando +4 more
core +1 more source
ChemMedChem, Volume 20, Issue 11, June 2, 2025.Antitubercular evaluation of a novel library of isoniazid‐dihydropyrimidinone molecular hybrids (8a–8n) discloses a potent compound with MIC = 0.39μg mL−1 against M. tuberculosis mc26230. Cytotoxicity, stability, and in silico studies, including molecular docking and ADME/T (absorption, distribution, metabolism, excretion, and toxicity) analysis ...
Gobind Kumar +10 more
wiley +1 more source
Cinchona-Derived Picolinamides: Effective Organocatalysts for Stereoselective Imine Hydrosilylation [PDF]
, 2014 Picolinamide-cinchona organocatalysts for the successful enantioselective reduction of ketomines were developed. For the first time, a new type of chiral Lewis base, a cationic species, is reported to efficiently organocatalyze the addition of ...
Andrea, Genoni +3 more
core +1 more source
Catalysis With Deep Eutectic Solvents: Challenges and Opportunities
ChemCatChem, Volume 17, Issue 11, June 6, 2025.Deep eutectic solvents (DESs) are emerging as sustainable alternatives in catalysis, offering tunable properties for diverse chemical transformations. This review explores the dual role of DESs as solvents and catalysts, highlighting advancements in organic chemistry, materials science, CO2 fixation, biomass valorization, polymer degradation, and ...
Eduardo Guzmán
wiley +1 more source
Journal of Chemistry, 2013 A simple and efficient method for the one-pot Biginelli condensation reaction of aldehydes, β-dicarbonyl compounds, and urea or thiourea employing [DABCO](SO3H)2Cl2 as a novel ionic liquid catalyst is described.
Firouzeh Nemati, Sara G. Alizadeh
doaj +1 more source
Recent Advances in Biocatalytic Promiscuity: Hydrolase-Catalyzed Reactions for Nonconventional Transformations [PDF]
, 2015 Financial support from the Spanish Ministerio de Economía y Competitividad (CTQ2013-44153-P) is grateful acknowledged. M.L.-I.
Gotor Fernández, Vicente +1 more
core +2 more sources
Dihydropyrimidinone Based Chromones as New α‐Glucosidase Inhibitors
ChemistrySelect, Volume 10, Issue 21, June 4, 2025.1‐(2,4‐Dihydroxyphenyl)ethanone functions as a fundamental precursor in the synthesis of dihydropyrimidinone conjugates that incorporate both chromone and triazole moieties. Docking analyses are performed on 15 synthetic compounds. In silico investigations confirm high binding affinity, with docking energies of −10.7 kcal/mol for compound 5a and −10.9 ...
Kumara Swamy Taviti +6 more
wiley +1 more source
Capture–Collapse Heterocyclization:1,3-Diazepanes by C–N Reductive Elimination from Rhodacyclopentanones [PDF]
, 2016 Rhodacyclopentanones derived from carbonylative C–C activation of cyclopropyl ureas can be “captured” by pendant nucleophiles prior to “collapse” to 1,3-diazepanes.
Bower, John +2 more
core +6 more sources
ChemistrySelect, Volume 10, Issue 22, June 11, 2025.A library of novel organochalcogen‐DHPM‐triazole hybrids was developed using a rapid, simple, and ultrasound‐assisted method. Additionally, all compounds underwent comprehensive theoretical, photophysical, and electrochemical characterization, providing relevant insights for future biological applications.
Amanda R. Azevedo +4 more
wiley +1 more source