Results 91 to 100 of about 1,953 (199)

Highly Enantioselective Biginelli Reaction of Aliphatic Aldehydes Catalyzed by Chiral Phosphoric Acids [PDF]

, 2017
Several chiral phosphoric acids were evaluated as organocatalysts for the enantioselective Biginelli reaction of aliphatic aldehydes. With a chiral phosphoric acid derived from 3,3′-bis(3,5-di-tert-butyl-4-methoxyphenyl)-1,1′-binaphthalene-2,2′-diol, and
Zhenhua Gao, Hui Zhong, Yongbiao Guo, Chuanpin Zou, Huilan Yu, Xiangyan Meng, Guilan Huang, Xiaoqin Ding, Hui Tang   +8 more
core   +1 more source

Green and Efficient Synthesis of Dihydropyrimidinone Analogues via Hpa-Clay Catalyzed Biginelli Reaction

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry
This study introduces an environmentally sustainable approach for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs), via the Biginelli reaction. A heterogeneous catalyst, Heteropolyacid-Clay (HPA-Clay), is developed by immobilizing H5PV2W10O40 on ...
Nuzhat Rehman, Ayaz Mahmood Dar, Raja Feroz Ahmad Haji, Sharief-ud-din Khan, Deepak Pareek, Saleem Farooq, Bashir Ahmad Dar   +6 more
doaj   +1 more source

P(HEMA)-SO₃H catalyzed Biginelli reaction [PDF]

Dihidropirimidinonlar (DHPM)'ler farmasötik ve medikal kimyada çok önemli bileşiklerdir. Dihidropirimidinonların sentezi için en yaygın kullanılan yöntem, Biginelli reaksiyonu olarak bilinen, etil asetoasetat, aril aldehit ve üre (veya tiyoüre)’ nin ...
Berthe, Mamadou Lamine
core  

Ethyl (E)-4-(2,4-Dimethoxyphenyl)-6-(2,4-dimethoxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Molbank, 2017
A new compound belonging to the “heterostilbene” derivative, namely ethyl (E)-4-(2,4-dimethoxyphenyl)-6-(2,4-dimethoxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (2), has been successfully synthesized as an unprecedented side product of the ...
Hery Suwito, Lutfan Zulianto, Kautsar Ul Haq, Erwanto Erwanto, Abdulloh Abdulloh, Alfinda Novi Kristanti, Indriani Indriani   +6 more
doaj   +1 more source

A revision of the biginelli reaction under solid acid catalysis. Solvent-free synthesis of dihydropyrimidines over montmorillonite KSF [PDF]

, 1999
The reaction of aldehydes, β-dicarbonyl compounds and urea (Biginelli reaction) has been performed over solid acid catalysis, under solventless conditions or in water affording dihydropyrimidines in good yield and ...
Maggi R., Sartori G., Bigi F., Carloni S., Frullanti B.   +4 more
core   +1 more source

Skeletal rearrangement in Biginelli reaction for the synthesis of chromenoquinoline fused spirohydantoins and their in silico cytotoxicity study

Scientific Reports
Although Biginelli reaction is known to generate dihydropyrimidinones having wide arrays of phramacological properties, herein we report an unprecedented skeletal rearrangement in Biginelli reaction to synthesize pharmacologically versatile imidazolidine-
Mezhubeinuo, Hemanta Bordoloi, Anurag Pratim Saikia, Ghanashyam Bez   +3 more
doaj   +1 more source

Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones)

E-Journal of Chemistry, 2011
Trifluoroacetic acid (TFA) is introduced as an effective catalyst for promotion of Biginelli reaction. 3,4-Dihydropyrimidin-2(1H)-one (-thione) derivatives (DHPMs) were simply and efficiently prepared using TFA catalyzed one-pot, three-component ...
Mohammad R. Mohammadizadeh, Neda Firoozi
doaj   +1 more source

Biginelli Reaction Mediated Synthesis of Antimicrobial Pyrimidine Derivatives and Their Therapeutic Properties. [PDF]

Molecules, 2021
Marinescu M.
europepmc   +1 more source

The Three-Component Biginelli Reaction: A Combined Experimental and Theoretical Mechanistic Investigation [PDF]

, 2015
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Biginelli reactions have been monitored by direct infusion electrospray ionization mass spectrometry (ESI-MS) and key ...
Antunes, OAC, da Penha, ET, De Souza, ROMA, Esteves, PM, Milagre, HMS, Eberlin, MN, Garden, SJ   +6 more
core   +1 more source

Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca²⁺ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation. [PDF]

Molecules, 2022
Malek R, Simakov A, Davis A, Maj M, Bernard PJ, Wnorowski A, Martin H, Marco-Contelles J, Chabchoub F, Dallemagne P, Rochais C, Jozwiak K, Ismaili L.   +12 more
europepmc   +1 more source