Results 91 to 100 of about 2,041,750 (198)

Biginelli Reaction Mediated Synthesis of Antimicrobial Pyrimidine Derivatives and Their Therapeutic Properties. [PDF]

Molecules, 2021
Marinescu M.
europepmc   +1 more source

Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones)

E-Journal of Chemistry, 2011
Trifluoroacetic acid (TFA) is introduced as an effective catalyst for promotion of Biginelli reaction. 3,4-Dihydropyrimidin-2(1H)-one (-thione) derivatives (DHPMs) were simply and efficiently prepared using TFA catalyzed one-pot, three-component ...
Mohammad R. Mohammadizadeh, Neda Firoozi
doaj   +1 more source

Facts, Presumptions, and Myths on the Solvent-Free and Catalyst-Free Biginelli Reaction. What is Catalysis for?

, 2016
The current manuscript describes the role and importance of catalysis and solvent effects for the Biginelli multicomponent reaction. The overwhelming number of new catalysts and conditions recently published for the Biginelli synthesis, including in some
Aline L. de Oliveira (1589941), Heibbe C. B. de Oliveira (1358022), Tatiani B. Lima (1819279), Roberto Y. Souza (1819282), Haline G. O. Alvim (1819276), Fabricio M. Silva (1819285), Brenno A. D. Neto (1589932), Fabio C. Gozzo (104392), Wender A. da Silva (1795975)   +8 more
core   +1 more source

Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca²⁺ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation. [PDF]

Molecules, 2022
Malek R, Simakov A, Davis A, Maj M, Bernard PJ, Wnorowski A, Martin H, Marco-Contelles J, Chabchoub F, Dallemagne P, Rochais C, Jozwiak K, Ismaili L.   +12 more
europepmc   +1 more source

Investigation of the Biginelli reaction mechanism

, 2019
As reações multicomponentes receberam grande atenção na síntese orgânica e química medicinal, pois permitem o design de novas moléculas e produtos farmacêuticos, em especial, com grande complexidade estrutural e excelentes rendimentos.
Tejero, Tatiane Nicola
core  

Synthesis of diverse dihydropyrimidine-related scaffolds by fluorous benzaldehyde-based Biginelli reaction and post-condensation modifications

Beilstein Journal of Organic Chemistry, 2011
Dihydropyrimidinones and dihydropyrimidinethiones generated from the Biginelli reactions of perfluorooctanesulfonyl-attached benzaldehydes are used as common intermediates for post-condensation modifications such as cycloaddition, Liebeskind–Srogl ...
Bruno Piqani, Wei Zhang
doaj   +1 more source

A Brønsted acidic ionic liquid anchored to magnetite nanoparticles as a novel recoverable heterogeneous catalyst for the Biginelli reaction. [PDF]

RSC Adv, 2021
Oboudatian HS, Naeimi H, Moradian M.
europepmc   +1 more source

Post-polymerization modification via the Biginelli reaction to prepare water-soluble polymer adhesives

, 2017
A copolymer precursor containing the β-ketoester moiety has been modified through the Biginelli reaction to get several water-soluble adhesives which are comparable to commercial glues.
Zilin Wang, Yuan Zhao, Yongsan Li, Guoqiang Liu, Ying Yu, Xing Wang, Lei Tao, Lei Yang, Yen Wei   +8 more
core   +1 more source

Tungsten-substituted molybdophosphoric acid impregnated with kaolin: effective catalysts for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones via biginelli reaction. [PDF]

RSC Adv, 2021
Aher DS, Khillare KR, Chavan LD, Shankarwar SG.   +3 more
europepmc   +1 more source

O,S,Se-containing Biginelli products based on cyclic β-ketosulfone and their postfunctionalization

Beilstein Journal of Organic Chemistry
A one-pot three-component Biginelli synthesis of dihydropyrimidinones/thiones/selenones via acetic acid or solvent-free Yb(OTf)3-catalyzed tandem reaction of β-ketosulfone (dihydro-2H-thiopyran-3(4H)-one-1,1-dioxide), an appropriate urea, and ...
Kateryna V. Dil, Vitalii A. Palchykov
doaj   +1 more source