Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation. [PDF]
Malek R +12 more
europepmc +1 more source
Biginelli multicomponent reactions
Biginelli reaction is one of the most remarkable examples of MCRs discovered in 1893 and proof of its importance is the high number of articles reported in the last decade covering this field. This strategy allows the synthesis of important building blocks and versatile synthons such as 3,4-dihydropyrimidin-2-(1H)-one derivatives (DHPMs), which are ...
Marqués-López, Eugenia +1 more
openaire +1 more source
A new compound belonging to the “heterostilbene” derivative, namely ethyl (E)-4-(2,4-dimethoxyphenyl)-6-(2,4-dimethoxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (2), has been successfully synthesized as an unprecedented side product of the ...
Hery Suwito +6 more
doaj +1 more source
A four-component modified Biginelli reaction: A novel approach for C-2 functionalized dihydropyrimidines. [PDF]
Narkhede H, Dhake A, Balasubramaniyan V.
europepmc +1 more source
Synthesis of arylpiridines with us on bifuntional catalysts Me/SiO2-SO3H (Me= Au, Ir, Pt) [PDF]
Se estudió la reacción multicomponente de Hantzsch para la obtención de compuestos derivados de la familia 2-arilpiridinas, usando catalizadores bifuncionales tipo Me/SiO2-SO3H (Me = Au, Pt, Ir). Los catalizadores se caracterizaron por distintas técnicas
Martinez, José +4 more
core
Methyl 6-Methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate
Methyl 6-methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate has been synthesized via Biginelli reaction of 4-iodobenzaldehyde, methyl acetoacetate and thiourea, promoted by microwave irradiation in the presence of iodine under ...
Qingjian Liu, Ning Pan, Wenwen Zhang
doaj +1 more source
Synthesis, Leishmanicidal and Cytotoxic Activity of Triclosan-Chalcone, Triclosan-Chromone and Triclosan-Coumarin Hybrids [PDF]
Twelve hybrids derived from triclosan were obtained via Williamson etherification of O-triclosan alkyl bromide plus chalcone and O-coumarin or O-chromone alkyl bromide plus triclosan, respectively.
Carda, Miguel +7 more
core +2 more sources
The introduction of Mannich and Biginelli multicomponent reactions in a practical Organic Chemistry course is presented in this article. Procedures described in the literature were adapted for use under the simple conditions available in undergraduate ...
Marcelo Volpatto Marques +2 more
doaj +1 more source
A Brønsted acidic ionic liquid anchored to magnetite nanoparticles as a novel recoverable heterogeneous catalyst for the Biginelli reaction. [PDF]
Oboudatian HS, Naeimi H, Moradian M.
europepmc +1 more source
Tungsten-substituted molybdophosphoric acid impregnated with kaolin: effective catalysts for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones via biginelli reaction. [PDF]
Aher DS +3 more
europepmc +1 more source

