Results 111 to 120 of about 3,427 (216)

Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation. [PDF]

open access: yesMolecules, 2022
Malek R   +12 more
europepmc   +1 more source

Biginelli multicomponent reactions

open access: yes, 2015
Biginelli reaction is one of the most remarkable examples of MCRs discovered in 1893 and proof of its importance is the high number of articles reported in the last decade covering this field. This strategy allows the synthesis of important building blocks and versatile synthons such as 3,4-dihydropyrimidin-2-(1H)-one derivatives (DHPMs), which are ...
Marqués-López, Eugenia   +1 more
openaire   +1 more source

Ethyl (E)-4-(2,4-Dimethoxyphenyl)-6-(2,4-dimethoxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

open access: yesMolbank, 2017
A new compound belonging to the “heterostilbene” derivative, namely ethyl (E)-4-(2,4-dimethoxyphenyl)-6-(2,4-dimethoxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (2), has been successfully synthesized as an unprecedented side product of the ...
Hery Suwito   +6 more
doaj   +1 more source

Synthesis of arylpiridines with us on bifuntional catalysts Me/SiO2-SO3H (Me= Au, Ir, Pt) [PDF]

open access: yes, 2016
Se estudió la reacción multicomponente de Hantzsch para la obtención de compuestos derivados de la familia 2-arilpiridinas, usando catalizadores bifuncionales tipo Me/SiO2-SO3H (Me = Au, Pt, Ir). Los catalizadores se caracterizaron por distintas técnicas
Martinez, José   +4 more
core  

Methyl 6-Methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate

open access: yesMolbank, 2009
Methyl 6-methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate has been synthesized via Biginelli reaction of 4-iodobenzaldehyde, methyl acetoacetate and thiourea, promoted by microwave irradiation in the presence of iodine under ...
Qingjian Liu, Ning Pan, Wenwen Zhang
doaj   +1 more source

Synthesis, Leishmanicidal and Cytotoxic Activity of Triclosan-Chalcone, Triclosan-Chromone and Triclosan-Coumarin Hybrids [PDF]

open access: yes, 2014
Twelve hybrids derived from triclosan were obtained via Williamson etherification of O-triclosan alkyl bromide plus chalcone and O-coumarin or O-chromone alkyl bromide plus triclosan, respectively.
Carda, Miguel   +7 more
core   +2 more sources

Reações multicomponentes de Biginelli e de Mannich nas aulas de química orgânica experimental: uma abordagem didática de conceitos da química verde

open access: yesQuímica Nova, 2012
The introduction of Mannich and Biginelli multicomponent reactions in a practical Organic Chemistry course is presented in this article. Procedures described in the literature were adapted for use under the simple conditions available in undergraduate ...
Marcelo Volpatto Marques   +2 more
doaj   +1 more source

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