Results 171 to 180 of about 3,427 (216)

Aminoheterocycles as synthons for combinatorial Biginelli reactions

Molecular Diversity, 2010
Chlorotrimethylsilane (TMSCl) has been utilized as an efficient promoter and water scavenger in the synthesis of diverse dihydropyrimidines via Biginelli type MCR-heterocyclization using aminoheterocycles. High yields and a simple workup of target compounds enable the facile generation of combinatorial libraries comprising more than 2,000 compounds of ...
Sergey V, Ryabukhin, Andrey S, Plaskon, Sergey Yu, Boron, Dmitriy M, Volochnyuk, Andrey A, Tolmachev   +4 more
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Recent progress in asymmetric Biginelli reaction

Molecular Diversity, 2013
The Biginelli reaction, which involves the interaction of ethyl acetoacetate, urea, and an appropriate aryl aldehyde, was first discovered by Pietro Biginelli about 120 years ago. The Biginelli products (3,4-dihydropyrimidin-2(1H)-ones) are interesting materials due to their significant pharmacological and structural profiles.
Majid M, Heravi, Shima, Asadi, Boshra Malekzadeh, Lashkariani   +2 more
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Tandem Hydroformylation-Biginelli Reaction

Synlett, 2013
The combination of a tandem process with a multicomponent reaction is a new approach to high atom-economic synthesis. A tandem hydroformylation–Biginelli reaction sequence has been developed leading to a variety of functionalized 4-alkyl-substituted 3,4-dihydropyrimidin-2(1H)-ones.
Fuchs, Daniela, Nasr-Esfahani, Mahboobeh, Diab, Lisa, Smejkal, Tomas, Breit, Bernhard   +4 more
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The Biginelli Reaction

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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Organosilane sulfonated graphene oxide in the Biginelli and Biginelli-like reactions

New Journal of Chemistry, 2016
The acid functionalized SSi-GO was used as a highly active, selective and reusable catalyst to improve the formation of pyrimidinones.
Javad Safari, Soheila Gandomi-Ravandi, Samira Ashiri   +2 more
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Biginelli Reaction: A Green Perspective

Current Organic Chemistry, 2012
The Biginelli Reaction is a one-pot acid catalysed cyclocondensation of -keto ester, urea and aromatic aldehyde which leads to the synthesis of functionalised 3,4-dihydro-2(H)-pyrimidinones (DHPMs). This three-component reaction for the synthesis of dihydro- pyrimidinone and corresponding dihydropyrimidinethiones has now been known for more than a ...
Siva S. Panda, Pankaj Khanna, Leena Khanna   +2 more
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The Biginelli Reaction Is a Urea-Catalyzed Organocatalytic Multicomponent Reaction

The Journal of Organic Chemistry, 2015
The recently developed artificial force induced reaction (AFIR) method was applied to search systematically all possible multicomponent pathways for the Biginelli reaction mechanism. The most favorable pathway starts with the condensation of the urea and benzaldehyde, followed by the addition of ethyl acetoacetate.
Maneeporn, Puripat, Romain, Ramozzi, Miho, Hatanaka, Waraporn, Parasuk, Vudhichai, Parasuk, Keiji, Morokuma   +5 more
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New catalysts of Biginelli reaction

Russian Journal of Organic Chemistry, 2007
A synthesis was developed of new imidazole derivatives catalyzing three-component condensation of ethyl acetoacetate, aromatic aldehydes, and urea(or thiourea) by Biginelli reaction.
F. Makaev, E. Styngach, V. Muntyanu, S. Pogrebnoi, Z. Rybkovskaya, A. Barba   +5 more
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2-Acylthioacetamides in the Biginelli Reaction

Chemistry of Heterocyclic Compounds, 2014
We have demonstrated for the first time a Biginelli reaction of 2-acylthioacetamides with aromatic aldehydes and ureas or thioureas, leading to N-Ar1-4-Ar2-6-R1-1-R2-2-oxo(thioxo)-1,2,3,4-tetrahydro-pyrimidine-5-carbothioamides. The regioselectivity of this process matched the concept of hard/soft Lewis acids and bases.
M. N. Kurmach, A. B. Ryabitskiy, V. N. Britsun   +2 more
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ChemInform Abstract: Biginelli Reaction

ChemInform, 2008
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Anil Saini, Sanjay Kumar, Jagir S. Sandhu   +2 more
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