Results 51 to 60 of about 19,462 (277)
Where does the lactate come from? A rare cause of reversible inhibition of mitochondrial respiration [PDF]
, 2010 Biguanide poisoning is associated with lactic acidosis. The exact mechanism of biguanide-induced lactic acidosis is not well understood. In the previous issue of Critical Care, Protti and colleagues demonstrated that biguanide-induced lactic acidosis may
Levy, Bruno +2 more
core +2 more sources
Annals of Gastroenterological Surgery, EarlyView.This meta‐analysis compared olanexidine gluconate (OLG) with conventional antiseptics on surgical site infections (SSIs) in gastroenterological surgery. OLG significantly reduced overall SSIs without statistical heterogeneity. Abstract Aim To compare the preventative effect of the new antiseptic olanexidine gluconate (OLG) with conventional antiseptics
Akihisa Matsuda +4 more
wiley +1 more source
Zur Kenntniss des Biguanids [PDF]
Berichte der deutschen chemischen Gesellschaft, 1892 n ...
Bamberger, E.-U.-G., Dieckmann, W.
openaire +2 more sources
Early drug use of dapagliflozin prescribed by general practitioners and diabetologists in Germany. [PDF]
, 2016 OBJECTIVES: Dapagliflozin is an inhibitor of the human sodium-glucose co-transporter 2 (SGLT2) that has been shown to improve glycaemic control in patients with type 2 diabetes mellitus (T2DM).
Hammar, Niklas +3 more
core +1 more source
Hydrogel‐Based Smart Materials for Wound Healing and Sensing
Aggregate, EarlyView.The graphical abstract illustrates the role of hydrogel‐based flexible materials in advancing biomedical applications, including wound healing, point‐of‐care diagnostics, smart patches, and wearable devices. Hydrogels are particularly promising in modern wound care due to their high‐water content, flexibility, and biocompatibility.
Thi Kim Ngan Duong +11 more
wiley +1 more source
Canadian Journal of Infectious Diseases and Medical Microbiology, 2013 Fungal osteomyelitis is rare in immunocompetent patients and is often difficult to cure, even with optimal medical and surgical management. The authors present two cases of fungal osteomyelitis in which the common swimming pool cleaner, polyhexamethylene
Genevieve Walls +4 more
doaj +1 more source
Biguanide iridium(III) complexes with potent antimicrobial activity [PDF]
, 2018 We have synthesized novel organoiridium(III) antimicrobial complexes containing a chelated biguanide, including the antidiabetic drug metformin. These 16- and 18-electron complexes were characterized by NMR, ESI-MS, elemental analysis, and X-ray ...
Chen, Feng +8 more
core +2 more sources
Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies
Chemistry &Biodiversity, EarlyView.Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang +8 more
wiley +1 more source
Biguanide-, imine-, and guanidine-based networks as catalysts for transesterification of vegetable oil [PDF]
, 2010 Polycationic systems based on poly(hexamethylene biguanide) (PHMBG), branched polyethyleneimine (PEI) and poly(N-vinylguanidine) (PVG) have been evaluated as heterogeneous catalysts for the transesterification of sunflower oil by methanol.
Alvarez, Michael +4 more
core +1 more source
Insulin and Metformin are Associated With Reduced Risk of Amyotrophic Lateral Sclerosis
Chronic Diseases and Translational Medicine, EarlyView.Human insulin heterodimer (A). Human insulin heterodimer (dark blue) docked within center of Cx43 channel (B) Abstract Background Type 2 diabetes (T2D), but not type 1, protected against amyotrophic lateral sclerosis (ALS). In T2D serum insulin is normal or elevated in the early stages.
Steven Lehrer, Peter H. Rheinstein
wiley +1 more source