Results 71 to 80 of about 19,462 (277)

Reaction of Biguanides and Related Compounds. II. Reaction of Biguanides with Benzil

open access: yesChemical and Pharmaceutical Bulletin, 1972
Heating of 1-substituted biguanide with benzil in ethanol was found to give 2-substituted guanidilidene-5, 5-diphenylhydantoin, which was easily converted into 1, 1-diphenyl-1-substituted biguanidoacetic acid by hydrolysis with hydrochloric acid. The structureand the formation mechanism of 2-substituted guanidilidene-5, 5-diphenylhydantoin was also ...
Yoko Kojima   +3 more
openaire   +3 more sources

Scedosporium prolificans Septic Arthritis [PDF]

open access: yes, 2017
Scedosporium prolificans is an emerging fungal pathogen that can cause significant morbidity, and even mortality, in both immunocompromised and immunocompetent patients.
Frankenhoff, Jessica A.   +2 more
core   +1 more source

The Effect of Various Irrigants on Mixed Biofilms in Dentinal Tubules: A Confocal Laser Scanning Microscopy Study

open access: yesMicroscopy Research and Technique, EarlyView.
This study evaluated the disinfection efficacy of various irrigation solutions against mixed biofilms in dentinal tubules. The findings of CLSM analysis and viable bacterial sampling revealed that combined irrigation solutions were significantly more effective than single solutions, supporting their use as the preferred approach in clinical practice ...
Dide Tekinarslan   +4 more
wiley   +1 more source

BrazIliaN Type 1 & 2 DiabetEs Disease Registry (BINDER): longitudinal, real-world study of diabetes mellitus control in Brazil

open access: yesFrontiers in Clinical Diabetes and Healthcare, 2022
IntroductionThis study aimed at assessing the patterns of care and glycemic control of patients with diabetes (DM) in real life during a follow-up of 2 years in the public and private health sectors in Brazil.MethodsBINDER was an observational study of ...
Bianca de Almeida-Pititto   +3 more
doaj   +1 more source

The pathogenesis of Acanthamoeba infections: current status and future implications [PDF]

open access: yes, 2004
Acanthamoeba are opportunistic protozoan parasites that can cause painful, visionthreatening keratitis. However the pathogenesis and pathophysiology of Acanthamoeba keratitis remain incompletely understood. Most cases of Acanthamoeba keratitis develop
Khan, Naveed Ahmed
core  

Metformin reverses periodontal destruction caused by experimental periodontitis by inhibiting interleukin‐1β activity

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis is a destructive disease that affects periodontal tissue. While current research focuses on disease management, research on tissue repair remains limited. Metformin, a first‐line medication for diabetes treatment, has positive effects on bone health in nondiabetic patients.
Zhao Wang   +10 more
wiley   +1 more source

Bilateral Acanthamoeba keratitis [PDF]

open access: yes, 2012
Acanthamoeba keratitis is a rare eye infection commonly misdiagnosed as herpes simplex or fungal keratitis. Failure to include it in the differential diagnosis in any contact lens wearer with the typical features of an eye infection, results in a ...
Cachia Markham, Mark, Mercieca, Franco
core  

Does microbicide use in consumer products promote antimicrobial resistance? A critical review and recommendations for a cohesive approach to risk assessment [PDF]

open access: yes, 2013
The increasing use of microbicides in consumer products is raising concerns related to enhanced microbicide resistance in bacteria and potential cross resistance to antibiotics.
Bloomfield, Sally   +12 more
core   +3 more sources

Gramicidin and chlorhexidine encapsulated in bicontinuous microemulsions: Antimicrobial activity performance and their impact on self‐assembly

open access: yesJournal of Surfactants and Detergents, EarlyView.
Interaction of gramicidin D (gD) and chlorhexidine (CH) with the surfactant monolayers of bicontinuous microemulsions. Abstract The utility of bicontinuous microemulsions (BMEs) as carriers of the antimicrobial peptide (AMP) gramicidin D and antiseptic chlorhexidine was investigated for possible topical delivery to chronic wounds.
Douglas G. Hayes   +6 more
wiley   +1 more source

Liver uptake of Biguanides in rats

open access: yesBiomedicine & Pharmacotherapy, 2011
Metformin is an oral antihyperglycaemic agent widely used in the management of non-insulin-dependent diabetes mellitus. The liver is the primary target, metformin being taken up into human and rat hepatocytes via an active transport mechanism. The present study was designed to compare hepatic uptake of two biguanides, metformin and phenformin, in vitro
Setsuko Komuro   +3 more
openaire   +3 more sources

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