Results 211 to 220 of about 391,701 (312)

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

ACT001 alleviates MASLD through gut microbiota-bile acid-FXR axis in mice. [PDF]

Ann Med
Niu B, Liu J, Zhou H, Chu W, Wu X, Zhou Y, Chen Z, Liu Y, Mi Y, Li P.   +9 more
europepmc   +1 more source

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source

Secondary Bile Acid Derivatives Are Contributors to the Fecal Bile Acid Pool and Associated With Bile Acid-Modulating Nutrients. [PDF]

J Nutr
Wolf PG, Welsh C, Binion B, Dai H, Oliveira ML, Hamm A, Goldberg S, Buobu PS, Schering T, Vergis S, Kessee N, Gomez SL, Yazici C, Maienschein-Cline M, Byrd DA, Gaskins HR, Ridlon JM, Mutlu E, Greening C, Tussing-Humphreys L.   +19 more
europepmc   +1 more source

Expression of bile acid receptor TGR5 in gastric adenocarcinoma

, 2012
Weibiao Cao, Wei Tian, Jie Hong, Dan Li, Rosemarie Tavares, Lelia Noble, Steven F. Moss, Murray B. Resnick   +7 more
openalex   +2 more sources

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Formylated Bile Acid-Steroid Conjugates: Synthesis, Antifungal Properties, and <i>In Silico</i> Studies. [PDF]

ACS Omega
Hajdaś G, Kułaga D, Koenig H, Starzyk J, Maliugin V, Pospieszny T.   +5 more
europepmc   +1 more source

Intestinal bile acid absorption [PDF]

, 1993
Girbig, Frank, Gutjahr, Ulrike, Jouvenal, Karin, Kowalewski, Simone, Kramer, Werner, Müller, Günter, Tripier, Dominique, Wess, Günther   +7 more
core  

Hydroxyl/bile acid exchange. A new mechanism for the uphill transport of cholate by basolateral liver plasma membrane vesicles.

, 1986
Bennett L. Blitzer, C Terzakis, Kenneth A. Scott   +2 more
openalex   +1 more source

Drug poisonings following bariatric surgery: Case series report

British Journal of Clinical Pharmacology, EarlyView.
Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari, Fannie LaJeunesse‐Trempe, Stephen Morley, Caroline Copeland   +3 more
wiley   +1 more source