Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives
ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos+8 more
wiley +1 more source
Balance between bile acid conjugation and hydrolysis activity can alter outcomes of gut inflammation. [PDF]
Fu Y+9 more
europepmc +1 more source
Nobiletin Enhances Skeletal Muscle Mass and Modulates Bile Acid Composition in Diet-Induced Obese Mice. [PDF]
Koh YC+6 more
europepmc +1 more source
The preparation of the unconjugated acids of ox‐bile
Samuel Barnett Schryver
openalex +2 more sources
Lipid Metabolism and Immune Function: Chemical Tools for Insights into T‐Cell Biology
This review explores how lipids regulate immune responses, particularly in T‐cell function. Advances in metabolomics and proteomics provide insights into lipid‐mediated immunity. Fluorescent lipids enable single‐cell analysis of lipid uptake and metabolism.
Luuk Reinalda+2 more
wiley +1 more source
Circulating bile acid profiles characteristics and the potential predictive role in clear cell renal cell carcinoma progression. [PDF]
Wang QC+12 more
europepmc +1 more source
Diagnostic and clinical relevance of targeted metabolomic analysis of serum bile acid profiles in acute pancreatitis. [PDF]
Guo C, Yong W, Yao B, Song L, Liang L.
europepmc +1 more source
Cutting‐Edge Aptasensing Approaches for Electrochemical Detection of Exosomes Utilizing MXenes
This work notably summarizes research on 2D MXenes/MXene's‐hybrid‐based nanoplatforms patterned with aptamers as an alternative to antibodies affording highly sensitive and robust biosensing of exosomes as well as their efficient isolation. The exosomes are highlighted as a valuable source of biomarkers and with the immobilization approaches of ...
Andrej Vikartovský+5 more
wiley +1 more source