Results 231 to 240 of about 238,773 (337)
Regulation of bile acids and their receptor FXR in metabolic diseases. [PDF]
Front NutrLi Y, Wang L, Yi Q, Luo L, Xiong Y.
europepmc +1 more source
Cancer Communications, EarlyView.Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu +12 more
wiley +1 more source
Bile acids and incretins as modulators of obesity-associated atherosclerosis. [PDF]
Front Cardiovasc MedKirsch A +3 more
europepmc +1 more source
Ubiquitination in cancer: mechanisms and therapeutic opportunities
Cancer Communications, EarlyView.Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu +7 more
wiley +1 more source
Bile acids enhance fat metabolism and skeletal muscle development in Zhijiang duck by modulating gut microbiota. [PDF]
Poult SciChen L +5 more
europepmc +1 more source
Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives
Chemistry &Biodiversity, EarlyView.ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos +8 more
wiley +1 more source
The association of serum total bile acids and deep venous thrombosis. [PDF]
Thromb JLi B +9 more
europepmc +1 more source