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Towards the clinical use of peripheral bile acids: Recommendations to limit their preanalytical and analytical sources of variability. [PDF]
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Stero-Bile Acids and Bile Sterols
The Journal of Biochemistry, 1961Abstract Cholesterol-4- 14 C was injected intraperitoneally into carp (Family Cyprinidae) and radioactive 5α-cyprinol, 5α- cholestane-3α,7α,12α,26,27-pentol that is the chief constituent of carp bile, was isolated from the gall bladder. This bile alcohol was characterized as the sulfate ester.
TARO KAZUNO +2 more
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Gastroenterology Clinics of North America, 1999
Bile acids undergo a unique enterohepatic circulation, which allows them to be efficiently reused with minimal loss. With the cloning of key bile acid transporter genes in the liver and intestine, clinicians now have a detailed understanding of how the different components in the enterohepatic circulation operate.
R J, Bahar, A, Stolz
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Bile acids undergo a unique enterohepatic circulation, which allows them to be efficiently reused with minimal loss. With the cloning of key bile acid transporter genes in the liver and intestine, clinicians now have a detailed understanding of how the different components in the enterohepatic circulation operate.
R J, Bahar, A, Stolz
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Annual Review of Physiology, 1983
Cholesterol is the obligatory precursor of bile acids, and the liver is the sole source and site of bile acid formation (1). In the transformation of choles terol to bile acids, the cyclopentanophenanthrene nucleus is first believed to undergo modifications followed by oxidation and cleavage of the choles terol side-chain.
G, Salen, S, Shefer
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Cholesterol is the obligatory precursor of bile acids, and the liver is the sole source and site of bile acid formation (1). In the transformation of choles terol to bile acids, the cyclopentanophenanthrene nucleus is first believed to undergo modifications followed by oxidation and cleavage of the choles terol side-chain.
G, Salen, S, Shefer
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Current Opinion in Lipidology, 1995
The sodium-dependent bile acid transporters and sodium-independent organic anion transporters are integral membrane glycoproteins that function in the enterohepatic circulation of bile acids. The recent cloning and expression of different classes of bile acid transporters have provided insights into their structure and molecular mechanism.
P A, Dawson, P, Oelkers
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The sodium-dependent bile acid transporters and sodium-independent organic anion transporters are integral membrane glycoproteins that function in the enterohepatic circulation of bile acids. The recent cloning and expression of different classes of bile acid transporters have provided insights into their structure and molecular mechanism.
P A, Dawson, P, Oelkers
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Annual Review of Biochemistry, 1975
INTRODUCTION 233 FORMATION OF BILE ACIDS 234 5fl Bile Acids 234 5~ Bile Acids 236 7c~ Hydroxylation of Cholesterol 237 12o~ Hydroxylation 238 26 Hydroxylation 238 Oxidation of 5fl-Chole~tane-3c~,7~t,12~,26-tetrol 239 METABOLISM OF BILE ACIDS 239 Conju,qation with Glycine and Taurine 240 Esterification with Sulfute and Glucuronic ...
H, Danielsson, J, Sjövall
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INTRODUCTION 233 FORMATION OF BILE ACIDS 234 5fl Bile Acids 234 5~ Bile Acids 236 7c~ Hydroxylation of Cholesterol 237 12o~ Hydroxylation 238 26 Hydroxylation 238 Oxidation of 5fl-Chole~tane-3c~,7~t,12~,26-tetrol 239 METABOLISM OF BILE ACIDS 239 Conju,qation with Glycine and Taurine 240 Esterification with Sulfute and Glucuronic ...
H, Danielsson, J, Sjövall
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The Journal of Clinical Pharmacology, 1990
The bile acid sequestrants, cholestyramine and colestipol, are the drugs of choice for the treatment of patients with hypercholesterolemia caused by increases in LDL‐cholesterol levels without concurrent hypertriglyceridemia (type IIA and type IIB hyperlipoproteinemia). Longitudinal clinical studies with these drugs have shown their ability to slow the
M, Ast, W H, Frishman
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The bile acid sequestrants, cholestyramine and colestipol, are the drugs of choice for the treatment of patients with hypercholesterolemia caused by increases in LDL‐cholesterol levels without concurrent hypertriglyceridemia (type IIA and type IIB hyperlipoproteinemia). Longitudinal clinical studies with these drugs have shown their ability to slow the
M, Ast, W H, Frishman
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Biochemistry, 1992
To conclude, the last several years have seen a resurgence of interest in the biosynthesis of bile acids. This focus has come about due to the central roles that these molecules play in cholesterol and fat metabolism and due to recent advances in their chemistry, biochemistry, and molecular biology.
D W, Russell, K D, Setchell
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To conclude, the last several years have seen a resurgence of interest in the biosynthesis of bile acids. This focus has come about due to the central roles that these molecules play in cholesterol and fat metabolism and due to recent advances in their chemistry, biochemistry, and molecular biology.
D W, Russell, K D, Setchell
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