Results 261 to 270 of about 138,323 (307)
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Zeitschrift für allgemeine Mikrobiologie, 1982
AbstractThrough the isolation and identification of a wide variety of degradation products formed from bile acids by microorganisms, a unified scheme for the complete degradation of bile acids to carbon dioxide and water has been proposed and discussed.
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AbstractThrough the isolation and identification of a wide variety of degradation products formed from bile acids by microorganisms, a unified scheme for the complete degradation of bile acids to carbon dioxide and water has been proposed and discussed.
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Biochemistry, 1992
To conclude, the last several years have seen a resurgence of interest in the biosynthesis of bile acids. This focus has come about due to the central roles that these molecules play in cholesterol and fat metabolism and due to recent advances in their chemistry, biochemistry, and molecular biology.
D W, Russell, K D, Setchell
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To conclude, the last several years have seen a resurgence of interest in the biosynthesis of bile acids. This focus has come about due to the central roles that these molecules play in cholesterol and fat metabolism and due to recent advances in their chemistry, biochemistry, and molecular biology.
D W, Russell, K D, Setchell
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Current Opinion in Lipidology, 1995
The sodium-dependent bile acid transporters and sodium-independent organic anion transporters are integral membrane glycoproteins that function in the enterohepatic circulation of bile acids. The recent cloning and expression of different classes of bile acid transporters have provided insights into their structure and molecular mechanism.
P A, Dawson, P, Oelkers
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The sodium-dependent bile acid transporters and sodium-independent organic anion transporters are integral membrane glycoproteins that function in the enterohepatic circulation of bile acids. The recent cloning and expression of different classes of bile acid transporters have provided insights into their structure and molecular mechanism.
P A, Dawson, P, Oelkers
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Archives of Internal Medicine, 1972
In 1967 a conference, largely organized by Leon Schiff, MD, was held in Cincinnati. Many of the investigators active in the field of bile acid metabolism presented their work. The proceedings of that conference, subsequently published in book form, 1 contained most of the information available at that time on the biochemistry and physiology of bile ...
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In 1967 a conference, largely organized by Leon Schiff, MD, was held in Cincinnati. Many of the investigators active in the field of bile acid metabolism presented their work. The proceedings of that conference, subsequently published in book form, 1 contained most of the information available at that time on the biochemistry and physiology of bile ...
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Hepatology, 1999
Uptake of drugs by bile acid carriers could account for the selectivity of drug actions in the gut and liver. We have previously shown that conjugation of xenobiotics with bile acids facilitates their transfer to hepatocytes and ileal enterocytes.
E, Petzinger +4 more
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Uptake of drugs by bile acid carriers could account for the selectivity of drug actions in the gut and liver. We have previously shown that conjugation of xenobiotics with bile acids facilitates their transfer to hepatocytes and ileal enterocytes.
E, Petzinger +4 more
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Species differences in bile acids II. Bile acid metabolism
Journal of Applied Toxicology, 2018AbstractOne of the mechanisms of drug‐induced liver injury (DILI) involves alterations in bile acid (BA) homeostasis and elimination, which encompass several metabolic pathways including hydroxylation, amidation, sulfation, glucuronidation and glutathione conjugation.
Rhishikesh Thakare +4 more
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Journal of Chromatography B: Biomedical Sciences and Applications, 1995
A review of the methods available for the separation of bile acids is presented, highlighting the most recent developments. The major chromatographic techniques (TLC, GC, HPLC) and combined detection systems for the determination of bile acids are critically evaluated and their advantages and disadvantages discussed.
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A review of the methods available for the separation of bile acids is presented, highlighting the most recent developments. The major chromatographic techniques (TLC, GC, HPLC) and combined detection systems for the determination of bile acids are critically evaluated and their advantages and disadvantages discussed.
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Bile acids. LIV—Mass spectra of conjugated bile acids
Biological Mass Spectrometry, 1978The electron impact mass spectra of conjugated bile acids, their 5alpha-analogs and methyl esters of glyco conjugates were determined by direct insertion into the ion source and their fragmentation patterns were found to be basically similar to those of methyl esters of the free bile acids. The conjugates are additionally characterized by a significant
R, Shaw, W H, Elliott
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Clinica Chimica Acta
As a large and structurally diverse family of small molecules, bile acids play a crucial role in regulating lipid, glucose, and energy metabolism. In the human body, bile acids share a similar chemical structure with many isomers, exhibit little difference in polarity, and possess various physiological activities.
Zhenhua Liu, Chongge You
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As a large and structurally diverse family of small molecules, bile acids play a crucial role in regulating lipid, glucose, and energy metabolism. In the human body, bile acids share a similar chemical structure with many isomers, exhibit little difference in polarity, and possess various physiological activities.
Zhenhua Liu, Chongge You
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Digestive Diseases, 1998
Bile acids normally undergo enterohepatic circulation. When this circulation is interrupted, bile acids enter the colon in increased concentrations. Here, they produce Cl<sup>–</sup> secretion by a calcium- and cyclic AMP-dependent mechanism, resulting in diarrhea.
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Bile acids normally undergo enterohepatic circulation. When this circulation is interrupted, bile acids enter the colon in increased concentrations. Here, they produce Cl<sup>–</sup> secretion by a calcium- and cyclic AMP-dependent mechanism, resulting in diarrhea.
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