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Urinary Bile Alcohols in Liver Dysfunction
Clinica Chimica Acta, 1987Bile alcohols are polyhydroxy steroids chemically related to bile acids and have long been regarded as major constituents of bile of primitive vertebrates [l]. Interest in bile alcohols increased when these compounds were found in both healthy and diseased humans as intermediates and side products of the normal pathway in bile acid biosynthesis [2,3 ...
Takahiko Hoshita +2 more
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Identification of bile alcohols in normal rabbit bile
Steroids, 1978Rabbit bile was examined for bile alcohols. Using combined gas chromatography-mass spectrometry, 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha, 25,26-pentol, 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha, 25--tetrol, 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha,24 beta-tetrol, 24-methyl-25-homo-5 beta-cholane-3 alpha, 7 alpha, 12 alpha, 24-tetrol, and 5 ...
M, Murata, T, Kuramoto, T, Hoshita
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Metabolism of bile alcohols in the perfused rabbit liver — C26 bile alcohols
Steroids, 1977The metabolism of a C26 bile alcohol (I, 24-nor-5beta-cho-lestane-3alpha, 7alpha,25-triol) was studied in the isolated perfused rabbit liver. The new bile alcohol and bile acid metabolites secreted into the bile were isolated and identified by a combination of TLC, GLC and GLC-MS.
B I, Cohen +4 more
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Isolation, quantitation, and identification of bile alcohols
Analytical Biochemistry, 1976A method was developed for the isolation, quantitation, and identification of new bile alcohols from bile. The compounds were formed from labeled bile alcohol precursors by the isolated perfused rabbit liver. The proposed method employs solvent extraction of free bile alcohols from the bile followed by qualitative and quantitative analysis of the ...
T, Kuramoto, B I, Cohen, E H, Mosbach
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Preparation of [3β-3H] labeled bile acids and bile alcohols
Steroids, 1979[3beta-3H]-bile acids and bile alcohols may be useful for metabolic studies in man and animals because the 3-position is invulnerable to bacterial attack. A number of tritium labeled bile acids and bile alcohols were prepared by selective oxidation of the hydroxyl group at carbon-3 followed by reduction with NaBT4. In each case, the bile acids and bile
B, Dayal +4 more
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Stero-bile acids and bile sterols. LVII. Chromatography of bile alcohols
Steroids, 1964Abstract This paper describes the column, paper and thin layer Chromatographic characteristics of 40 different bile alcohols that were synthesized or isolated from bile in this laboratory. Bile alcohols differing not only in number, character and position of polar groups but also in A/B ring junction and in length of the side chain are separable by ...
Taro Kazuno, Takahiko Hoshita
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Chemistry and Metabolism of Bile Alcohols and Higher Bile Acids
1968Publisher Summary This chapter discusses the chemistry and metabolism of bile alcohols and higher bile acids. The bile acids, occurring in the bile of mammals, birds, some snakes, and most bony fish are all mono-, di-or trihydroxy derivatives of the cholanoic acid.
T, Hoshita, T, Kazuno
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