Results 1 to 10 of about 276,357 (160)
Developing an Enzyme-Assisted Derivatization Method for Analysis of C27 Bile Alcohols and Acids by Electrospray Ionization-Mass Spectrometry [PDF]
Molecules, 2019 Enzyme-assisted derivatization for sterol analysis (EADSA) is a technology designed to enhance sensitivity and specificity for sterol analysis using electrospray ionization⁻mass spectrometry.
Jonas Abdel-Khalik +4 more
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Monitoring Atypical Metabolite Biomarkers in Patients with Bile Acid Synthesis Disorders by a Novel Targeted Tandem Mass Spectrometry Assay [PDF]
MetabolitesBackground/Objectives: Bile acid synthesis disorders (BASDs) represent a distinct category of progressive familiar cholestatic liver disease. A novel targeted mass spectrometry assay was developed for the accurate measurement of the major urinary ...
Kenneth D. R. Setchell +3 more
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Journal of Lipid Research, 1987 Urinary excretion of bile alcohols and bile acids in patients with complete extrahepatic cholestasis before and after the release by external biliary drainage was studied.
H Ichimiya, J Yanagisawa, F Nakayama
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Identification of bile alcohols in rat bile.
Journal of Lipid Research, 1989 Bile alcohols in rat bile were analyzed by gas-liquid chromatography-mass spectrometry. Six bile alcohols were newly identified as minor constituents in addition to 5 beta-cholestane-3 alpha,7 alpha,12 alpha,26-tetrol, major bile alcohol of rat bile. The
T Hiraoka +7 more
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Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2)[S]
Journal of Lipid Research, 2012 The apical Na+-dependent bile salt transporter (ASBT/SLC10A2) is essential for maintaining the enterohepatic circulation of bile salts. It is not known when Slc10a2 evolved as a bile salt transporter or how it adapted to substantial changes in bile salt ...
Daniël A. Lionarons +2 more
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Journal of Lipid Research, 1987 Large quantities of C27 bile alcohols hydroxylated at C-25 are excreted in the bile and urine of patients with cerebrotendinous xanthomatosis, a lipid storage disease that results from defective bile acid synthesis.
A K Batta +4 more
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Bile salts of vertebrates: structural variation and possible evolutionary significance[S]
Journal of Lipid Research, 2010 Biliary bile salt composition of 677 vertebrate species (103 fish, 130 reptiles, 271 birds, 173 mammals) was determined. Bile salts were of three types: C27 bile alcohols, C27 bile acids, or C24 bile acids, with default hydroxylation at C-3 and C-7.
Alan F. Hofmann +2 more
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Capillary gas-liquid chromatographic separation of bile alcohols.
Journal of Lipid Research, 1992 Gas-liquid chromatographic separation of C23, C24, C25, C26, and C27 bile alcohols with either 3 alpha, 7 alpha-dihydroxylated or 3 alpha, 7 alpha, 12 alpha-trihydroxylated ring system on two capillary columns, CP-Sil-19 CB and CP-Sil-5 CB, is described.
AK Batta +4 more
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Journal of Lipid Research, 2010 TGR5 is a G protein-coupled receptor that is activated by bile acids, resulting in an increase in cAMP levels and the subsequent modulation of energy expenditure in brown adipose tissue and muscle.
Yusuke Iguchi +5 more
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Identification of 5 beta-cholestane-3 alpha,7 alpha,12 alpha,24,25,26-hexol in human urine
Journal of Lipid Research, 1987 A new bile alcohol, 5 beta-cholestanehexol, was identified in the urine of healthy humans as the glucuronide. The bile alcohol glucuronide fraction was isolated by an ion exchange chromatography on piperidinohydroxypropyl Sephadex LH-20.
T Hiraoka +4 more
doaj +1 more source