The urine and feces of a patient with the rare inherited lipid storage disease, sitosterolemia and xanthomatosis, were analyzed. Substantial quantities of C26-bile alcohol, 26 (or 27)-nor-5 beta-cholestane-3 alpha,7 alpha,12 alpha,24S,25 xi-pentol along ...
B Dayal +5 more
doaj +1 more source
Effect of Intraduodenal Bile and Na-Taurodeoxycholate on Exocrine Pancreatic Secretion and on Plasma Levels of Secretin, Pancreatic Polypeptide, and Gastrin in Man [PDF]
The effect of intraduodenally administered cattle bile (CB) and Na-taurodeoxycholate (TDC) on basal pancreatic secretion and plasma levels of secretin, pancreatic polypeptide (PP), and gastrin were investigated on two separate days in 10 fasting ...
Fiedler, F. +6 more
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Optimal protection of stabilised dry live bacteria from bile toxicity in oral dosage forms by bile acid adsorbent resins [PDF]
We previously found that dried live bacteria of a vaccine strain can be temporarily sensitive to bile acids and suggested that Bile Adsorbing Resins (BAR) can be used in oral vaccine tablets to protect dried bacteria from intestinal bile. Here, we report
Slater, Nigel K.H. +10 more
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New synthetic bile acid analogue agonists of FXR and TGR5 receptors: Analytical methodologies for the study of their physico-chemical properties, pharmacokinetic activity and metabolism. [PDF]
This thesis reports an integrated analytical approach for the study of physicochemical and biological properties of new synthetic bile acid (BA) analogues agonists of FXR and TGR5 receptors.
Colliva, Carolina <1981>
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Bile acids: analysis in biological fluids and tissues
The formation of bile acids/bile alcohols is of major importance for the maintenance of cholesterol homeostasis. Besides their functions in lipid absorption, bile acids/bile alcohols are regulatory molecules for a number of metabolic processes.
J. Sjovall +4 more
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Bile Acid Derivatives as Enantiodifferentiating Host Molecules in Inclusion Processes
A review on the use of bile acids as hosts for molecular recognition and enantioresolution is presented. The optical resolution of different classes of organic derivatives, i.e., lactones, aliphatic alcohols, sulfoxides, epoxides, ketones, cyclic ...
Giancarlo Fantin +5 more
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The effect of liver warm ischaemia reperfusion injury and modulation on bile composition evaluated by magnetic resonance spectroscopy [PDF]
Orthotopic liver transplantation has become the preferred treatment for a variety of end-stage liver disease. As competency and survival rates increase, so does increasing demand, which puts greater strain on a static donor pool.
Hafez, T
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Biliary secretion of bile salts in mammals is mediated in part by the liver-specific ATP-dependent canalicular membrane protein Bsep/Spgp, a member of the ATP-binding cassette superfamily.
John H. Henson +7 more
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Modern Methods of Bile Acid Analysis by Mass Spectrometry: A View into the Metabolome
The advent of the “omics” revolution has reawakened an interest in the mass spectrometric analysis of bile acids, particularly in the related fields of lipidomics and metabolomics.
Yuqin Wang, William Griffiths
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Phylogenetic vision of bile acids Visión filogenética de los ácidos biliares. [PDF]
Bile acids are the most important solutes of bile: they are essential in cholesterol degradation, solubilization and excretion; they are determinants of bile flow and secretion; and their role is crucial in the intestinal absorption of lipids and lipid ...
Reyes Reyes, Consuelo
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