Results 91 to 100 of about 27,992 (288)

Adenocarcinoma in Caroli's Disease Treated by Liver Transplantation [PDF]

open access: yes, 1993
Caroli's disease is characterized by congenital cystic dilatation of the intrahepatic bile ducts.
Balsells, J.   +6 more
core   +3 more sources

Autocrine GDF10 Inhibits Hepatic Stellate Cell Activation via BMPR2/ALK3 Receptor to Prevent Liver Fibrosis

open access: yesAdvanced Science, EarlyView.
Liver fibrosis is a growing global health burden with no specific treatment. HSC activation is the predominant driver of liver fibrogenesis and the current focus in antifibrotic drug discovery. This study identifies autocrine GDF10 activates BMPR2/ALK3‐SMAD1/5/8‐SMAD7 pathway to counteract the TGF‐β‐SMAD2/3 pathway in HSCs, thereby inhibiting HSC ...
Yinliang Zhang   +16 more
wiley   +1 more source

Congenital dilatation of the intrahepatic bile ducts with cholangiocarcinoma [PDF]

open access: yesJournal of Clinical Pathology, 1972
Intrahepatic cholangiocarcinomas were found at necropsy in two previously reported cases of congenital dilatation of the intrahepatic bile ducts. The nature of the developmental abnormality is discussed and compared with other forms of biliary dilatation. Slow-flowing bile for many years probably leads to cholangiocarcinoma.
R. R. Millis   +2 more
openaire   +3 more sources

Generation of a High‐Precision Whole Liver Panorama and Cross‐Scale 3D Pathological Analysis for Hepatic Fibrosis

open access: yesAdvanced Science, EarlyView.
Using the MOSTtechnology and whole‐liver Nissl staining method, a multi‐structural 3D pathological panorama of liver fibrosis is obtained. The damaged sinusoids, steatotic hepatocytes, and collagen deposition are all concentrated in pericentral areas.
Xiaochuan Zhang   +13 more
wiley   +1 more source

Unclassified Diffuse Ductal Cholangiocarcinoma; Report of a Case

open access: yesCase Reports in Surgery, 2014
Cholangiocarcinoma (CCA) is the second most common malignant tumor of the liver. It is simply classified as intrahepatic and extrahepatic CCA (including perihilar and distal extra hepatic CCA) according to the anatomic localization.
Ünal Aydın   +6 more
doaj   +1 more source

Emergencies in neonatal management: jaundice and biliary atresia [PDF]

open access: yes, 2016
Biliary atresia is a severe and progressive inflammatory process of unknown cause, which initially involves the extrahepatic bile ducts but which quickly proceeds towards the intrahepatic bile tree leading rapidly to biliary cirrhosis. Biliary atresia is
Clemente, Maria Grazia   +1 more
core  

Liver resections: complications and survival outcome [PDF]

open access: yes, 2007
none1noToday, liver resection represents one of the most effective therapies in the treatment of defined liver diseases, particularly for hepatocellular carcinomas, liver metastases and tumors originating from the bile ducts.
Grazi, Gian Luca
core   +1 more source

Multiple cholangiocarcinomas in the intrahepatic and extrahepatic biliary tree due to dichloromethane exposure: a case report

open access: yesSurgical Case Reports, 2020
Background An outbreak of cholangiocarcinoma in Japan has led to widespread concern among workers in printing plants. In March 2013, the Japanese Ministry of Health, Labour and Welfare, confirmed a causal relationship between cholangiocarcinoma and long ...
Daisuke Ogawa   +9 more
doaj   +1 more source

Radiological imaging findings of the hepatic tuberculosis

open access: yesMedicine Science, 2021
This study aims to investigate the radiological findings of hepatic tuberculosis. Imaging findings of 8 patients diagnosed with biopsy-proven hepatic tuberculosis from January 2015 to March 2021 were retrospectively reviewed. The diagnosis of these cases
Mustafa Koc
doaj   +1 more source

Gut Microbiota-derived Bile Acids Promote Gamma-secretase Activity Through Interactions with Nicastrin Subunits [PDF]

open access: yesarXiv, 2023
Alzheimer's disease (AD) has emerged as a progressively pervasive neurodegenerative disorder worldwide. Bile acids, synthesized in the liver and modified by the gut microbiota, play pivotal roles in diverse physiological processes, and their dysregulation in individuals with AD has been well-documented.
arxiv  

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