Results 91 to 100 of about 27,992 (288)
Adenocarcinoma in Caroli's Disease Treated by Liver Transplantation [PDF]
Caroli's disease is characterized by congenital cystic dilatation of the intrahepatic bile ducts.
Balsells, J.+6 more
core +3 more sources
Liver fibrosis is a growing global health burden with no specific treatment. HSC activation is the predominant driver of liver fibrogenesis and the current focus in antifibrotic drug discovery. This study identifies autocrine GDF10 activates BMPR2/ALK3‐SMAD1/5/8‐SMAD7 pathway to counteract the TGF‐β‐SMAD2/3 pathway in HSCs, thereby inhibiting HSC ...
Yinliang Zhang+16 more
wiley +1 more source
Congenital dilatation of the intrahepatic bile ducts with cholangiocarcinoma [PDF]
Intrahepatic cholangiocarcinomas were found at necropsy in two previously reported cases of congenital dilatation of the intrahepatic bile ducts. The nature of the developmental abnormality is discussed and compared with other forms of biliary dilatation. Slow-flowing bile for many years probably leads to cholangiocarcinoma.
R. R. Millis+2 more
openaire +3 more sources
Using the MOSTtechnology and whole‐liver Nissl staining method, a multi‐structural 3D pathological panorama of liver fibrosis is obtained. The damaged sinusoids, steatotic hepatocytes, and collagen deposition are all concentrated in pericentral areas.
Xiaochuan Zhang+13 more
wiley +1 more source
Unclassified Diffuse Ductal Cholangiocarcinoma; Report of a Case
Cholangiocarcinoma (CCA) is the second most common malignant tumor of the liver. It is simply classified as intrahepatic and extrahepatic CCA (including perihilar and distal extra hepatic CCA) according to the anatomic localization.
Ünal Aydın+6 more
doaj +1 more source
Emergencies in neonatal management: jaundice and biliary atresia [PDF]
Biliary atresia is a severe and progressive inflammatory process of unknown cause, which initially involves the extrahepatic bile ducts but which quickly proceeds towards the intrahepatic bile tree leading rapidly to biliary cirrhosis. Biliary atresia is
Clemente, Maria Grazia+1 more
core
Liver resections: complications and survival outcome [PDF]
none1noToday, liver resection represents one of the most effective therapies in the treatment of defined liver diseases, particularly for hepatocellular carcinomas, liver metastases and tumors originating from the bile ducts.
Grazi, Gian Luca
core +1 more source
Background An outbreak of cholangiocarcinoma in Japan has led to widespread concern among workers in printing plants. In March 2013, the Japanese Ministry of Health, Labour and Welfare, confirmed a causal relationship between cholangiocarcinoma and long ...
Daisuke Ogawa+9 more
doaj +1 more source
Radiological imaging findings of the hepatic tuberculosis
This study aims to investigate the radiological findings of hepatic tuberculosis. Imaging findings of 8 patients diagnosed with biopsy-proven hepatic tuberculosis from January 2015 to March 2021 were retrospectively reviewed. The diagnosis of these cases
Mustafa Koc
doaj +1 more source
Gut Microbiota-derived Bile Acids Promote Gamma-secretase Activity Through Interactions with Nicastrin Subunits [PDF]
Alzheimer's disease (AD) has emerged as a progressively pervasive neurodegenerative disorder worldwide. Bile acids, synthesized in the liver and modified by the gut microbiota, play pivotal roles in diverse physiological processes, and their dysregulation in individuals with AD has been well-documented.
arxiv