Results 121 to 130 of about 88,892 (310)

A Machine Learning Model for Predicting Posthepatectomy Liver Failure After Hepatectomy With Extrahepatic Bile Duct Resection for Perihilar Cholangiocarcinoma: With and Without Indocyanine Green

Annals of Gastroenterological Surgery, EarlyView.
Using machine learning‐based decision tree models, patients with perihilar cholangiocarcinoma undergoing major hepatectomy with extrahepatic bile duct resection were stratified according to the risk of posthepatectomy liver failure. Separate models were developed with and without indocyanine green data, enabling clinically interpretable preoperative ...
Yuki Homma, Hiroki Ohya, Ryusei Matsuyama, Isamu Hosokawa, Tsukasa Takayashiki, Yusuke Ome, Shuichiro Uemura, Ryota Higuchi, Goro Honda, Eiryo Kawakami, Masayuki Ohtsuka, Itaru Endo   +11 more
wiley   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Magnetic resonance cholangio-pancreatography

Sakarya Tıp Dergisi, 2012
Magnetic resonance cholangiopancreatography (MRCP) is a noninvasive technique for evaluating the intrahepatic and extrahepatic bile ducts and the pancreatic duct.
Mustafa Kara, Yasemin Gündüz
doaj   +1 more source

An immunohistochemical study of the diagnostic value of TREM-1 as marker for fatal sepsis cases [PDF]

, 2019
Triggering receptor expressed on myeloid cells-1 (TREM-1) is produced and up-regulated by exposure of myeloid cells to lipopolysaccharides or other components of either bacterial or fungal origin, which causes it to be strongly expressed on phagocytes ...
Bolino, G., Fineschi, V., Frati, P., Maiese, A., Mastracchio, A.   +4 more
core   +1 more source

Effect of Broad‐Spectrum Antibiotic Prophylaxis on Post‐Pancreatoduodenectomy Infectious Complications: Nationwide Inpatient Database Study in Japan

Annals of Gastroenterological Surgery, EarlyView.
Using a nationwide Japanese inpatient database, we evaluated whether broad‐spectrum antibiotic prophylaxis improves postoperative outcomes after pancreatoduodenectomy compared with narrow‐spectrum antibiotics. In propensity score–weighted analyses of 45 099 patients, broad‐spectrum prophylaxis was associated with significantly lower rates of intra ...
Hiroki Kitagawa, Shotaro Aso, Yuki Hirano, Kenichiro Uemura, Keita Kouzu, Satoru Matsuda, Hiroki Matsui, Kiyohide Fushimi, Junichi Sasaki, Yuko Kitagawa, Hideo Yasunaga   +10 more
wiley   +1 more source

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

Hepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat, Kieran Hawthorne, Kenneth D. R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider, for Childhood Liver Disease Research Network (ChiLDReN)   +22 more
wiley   +1 more source

Optimizing the fluorescent visualization with Indocyanine green during laparoscopic cholecystectomy

Клиническая практика
BACKGROUND: The prevention of damaging the bile ducts during surgical interventions in patients with calculous cholecystitis remains a topical problem in modern abdominal surgery. The incidence of damaging the bile ducts reaches 0.4–2%, while in cases of
Mikhail V. Kosachenko, Alexander M. Leonovich, Aleksei E. Klimov, Anna V. Burlakova   +3 more
doaj   +1 more source

Mixed adenoneuroendocrine carcinoma of the extrahepatic bile duct: a case report

Journal of International Medical Research, 2019
Background The concept of mixed adenoneuroendocrine carcinoma (MANEC) was introduced in the 2010 World Health Organization classification of digestive neuroendocrine neoplasms. Bile duct invasion by MANEC is exceptionally rare. We herein report a case of
Hai-Wen Zhang, Kai Kou, Jun Qi, En-Bo Xie, Meng Wang, Yan Li, Guo-Yue Lv, Guang-Yi Wang   +7 more
doaj   +1 more source

Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology [PDF]

, 2013
Cholangiocytes are epithelial cells lining the biliary epithelium. Cholangiocytes play several key roles in the modification of ductal bile and are also the target cells in chronic cholestatic liver diseases (i.e., cholangiopathies) such as PSC, PBC ...
Alvaro, Domenico, Carpino, G, Franchitto, Antonio, Gaudio, Eugenio, Mancinelli, Romina, Onori, Paolo, Renzi, Anastasia   +6 more
core   +1 more source

Reappraisal of Real‐World Management of Acute Cholecystitis in Elderly Patients Based on the Adherence to Tokyo Guidelines 2018 (TG18): A Multicenter Study on Anzu HPB Surgical Meeting

Annals of Gastroenterological Surgery, EarlyView.
This multicenter retrospective study analyzes real‐world management of acute cholecystitis in patients aged ≥ 70 years across five institutions, focusing on adherence and intentional deviation from TG18 recommendations. By classifying treatment strategies as TG18‐accordant, more aggressive, or more conservative, we reappraise current practice patterns.
Yuta Kobayashi, Shojiro Hata, Ryo Oikawa, Tetsuya Nakazato, Hiroki Sakata, Hirokazu Yamaguchi, Yutaka Suzuki, Yoshihiro Sakamoto   +7 more
wiley   +1 more source