Results 21 to 30 of about 7,496 (209)
Frontiers in Marine Science, 2015 Biliverdin and bilirubin are breakdown products of normal heme catabolism, caused by the body's clearance of aged red blood cells which contain hemoglobin.
Sandra Barca +2 more
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Redox Biology, 2021 Background & aims: Plasma concentrations of bilirubin, a product of heme catabolism formed by biliverdin reductase A (BVRA), inversely associate with the risk of metabolic diseases including hepatic steatosis and diabetes mellitus in humans ...
Weiyu Chen +8 more
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CAQ Corner: Immune‐mediated complications
, 2022 Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley +1 more source
Direct antioxidant properties of bilirubin andbiliverdin. Is there a role for biliverdin reductase?
Frontiers in Pharmacology, 2012 Reactive oxygen species (ROS) and signaling events are involved in the pathogenesis of endothelial dysfunction and represent a major contribution to vascular regulation. Molecular signaling is highly dependent on reactive oxygen species. But depending on
Thomas eJansen, Andreas eDaiber
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Targeting Heme Oxygenase-1 in the Arterial Response to Injury and Disease
Antioxidants, 2020 Heme oxygenase-1 (HO-1) catalyzes the degradation of heme into carbon monoxide (CO), iron, and biliverdin, which is rapidly metabolized to bilirubin. The activation of vascular smooth muscle cells (SMCs) plays a critical role in mediating the aberrant ...
William Durante
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The limited prognostic value of liver histology in children with biliary atresia
Annals of Hepatology, 2015 Background and rationale for the study. The aim of the study was to determine the prognostic value of histopathological findings with special care to the severity of liver fibrosis at the moment of hepatopor-toenterostomy (HPE) in children with biliary ...
Piotr Czubkowski +5 more
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Okayama Igakkai Zasshi (Journal of Okayama Medical Association), 1978 Norio Nakamura
openaire +3 more sources
BMC Research Notes, 2017 Background Dubin–Johnson syndrome and intrahepatic cholestasis of pregnancy are rare chronic liver disorders. Dubin–Johnson syndrome may manifest as conjugated hyperbilirubinemia, darkly pigmented liver, presence of abnormal pigment in the parenchyma of ...
Grace Angeline Malarnangai Kularatnam +10 more
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Go Green: The Antiinflammatory Effects of Biliverdin Reductase
Frontiers in Pharmacology, 2012 Biliverdin (BV) has emerged as a cytoprotective and important anti-inflammatory molecule. Conversion of BV to bilirubin (BR) is catalyzed by biliverdin reductase (BVR) and is required for the downstream signaling and nuclear localization of BVR.
Barbara eWegiel, Leo eOtterbein
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Annals of Hepatology, 2005 Since the excretion of potentially toxic cholephilic organic anions (COAs) produced by the fetus, such as bile acids and biliary pigments, cannot be performed by the fetal liver alone, the placenta and the maternal liver must play a key role ...
José J.G. Marín +4 more
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