Bile pigments in pulmonary and vascular disease [PDF]
Frontiers in Pharmacology, 2012 The bile pigments, biliverdin and bilirubin, are endogenously-derived substances generated during enzymatic heme degradation. These compounds have been shown to act as chemical antioxidants in vitro. Bilirubin formed in tissues circulates in the serum,
Stefan W. Ryter
doaj +5 more sources
Bile pigments in emergency and critical care medicine [PDF]
European Journal of Medical Research, 2022 Bile pigments, such as bilirubin and biliverdin, are end products of the heme degradation pathway in mammals and are widely known for their cytotoxic effects.
Mizuki Seya +4 more
doaj +2 more sources
Effect of bile pigments on the compromised gut barrier function in a rat model of bile duct ligation. [PDF]
PLoS ONE, 2014 BACKGROUND: Studies have shown that the absence of bile in the gut lumen, either by bile duct ligation or bile diversion, induces mucosal injury. However, the mechanism remains elusive. In this study, the role of bile pigments in gut barrier function was
Kangkang Zhou +7 more
doaj +2 more sources
Evaluating the beneficial and detrimental effects of bile pigments in early and later life [PDF]
Frontiers in Pharmacology, 2012 The heme degradation pathway has been conserved throughout phylogeny and allows for the removal of a pro-oxidant and the generation of unique molecules including bile pigment with important cellular functions.
Phyllis A. Dennery
doaj +2 more sources
Quantification of Biliverdin, Bilirubin and Bilirubin Glucuronide in Micro-Samples of Animal Blood [PDF]
BiosensorsCirculating bile pigments are routinely measured in human and veterinary medicine, toxicology, pharmacology, and biomedical studies, as they are consolidated biomarkers of liver dysfunction and hemolysis and emerging biomarkers of biological responses to
Paola Sist +4 more
doaj +2 more sources
Predominance of Biliverdin over Bilirubin in Human Seminal Plasma [PDF]
BiomoleculesBiliverdin (BV) and bilirubin (BR) are established endogenous antioxidants and immune modulators in other organ systems; however, their roles in the male genital tract remain undefined.
Nina Hojnik +4 more
doaj +2 more sources
Distal renal tubular acidosis secondary to hyperbilirubinemia [PDF]
European Journal of Case Reports in Internal MedicineIntroduction: Bile cast nephropathy (BCN) is a rare and often overlooked cause of acute kidney injury (AKI), usually seen in the context of severe hyperbilirubinemia.
Fawzi Srour +5 more
doaj +2 more sources
The role of bile pigments in health and disease: effects on cell signaling, cytotoxicity and cytoprotection [PDF]
Frontiers in Pharmacology, 2012 Jaime eKapitulnik, Mahin D Maines
doaj +2 more sources
Liver histopathology in dogs with naturally acquired Babesia rossi infection [PDF]
Frontiers in Veterinary ScienceIntroductionIn sub-Saharan Africa, canine babesiosis, the most significant tick-borne disease in dogs, is primarily caused by the highly virulent intra-erythrocytic protozoan Babesia rossi, transmitted by ixodid ticks.
Heidi Horrell +3 more
doaj +2 more sources
Butterfly Wing Translucence Enables Enhanced Visual Signaling
Insects, 2023 The light reflected by the dorsal side of butterfly wings often functions as a signal for, e.g., mate choice, thermoregulation, and/or predator deterrence, while the ventral wing reflections are generally used for crypsis and camouflage. Here, we propose
Doekele G. Stavenga +2 more
doaj +1 more source