Combined Fluorometric Analysis of Biliverdin and Bilirubin by the Recombinant Protein HUG [PDF]
MethodsXBiliverdin is a secondary metabolite of heme catabolism. It is formed by the reaction catalyzed by heme oxygenase, which converts the heme group contained in proteins such as hemoglobin, myoglobin, cytochromes, and catalase into biliverdin, iron (II) and
Sabina Passamonti +2 more
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Predominance of Biliverdin over Bilirubin in Human Seminal Plasma [PDF]
BiomoleculesBiliverdin (BV) and bilirubin (BR) are established endogenous antioxidants and immune modulators in other organ systems; however, their roles in the male genital tract remain undefined.
Nina Hojnik +4 more
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Quantification of Biliverdin, Bilirubin and Bilirubin Glucuronide in Micro-Samples of Animal Blood [PDF]
BiosensorsCirculating bile pigments are routinely measured in human and veterinary medicine, toxicology, pharmacology, and biomedical studies, as they are consolidated biomarkers of liver dysfunction and hemolysis and emerging biomarkers of biological responses to
Paola Sist +4 more
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Proteomic analysis of Biliverdin protected cerebral ischemia–reperfusion injury in rats
Scientific Reports, 2023 Biliverdin, a heme metabolite, has been previously reported to alleviate cerebral ischemic reperfusion injury (CIRI). However, the alterations of brain proteome profiles underlying this treatment remain elusive.
Wenya Bai +5 more
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Biliverdin Inhibits Activation of NF-κB: Reversal of Inhibition by Human Biliverdin Reductase [PDF]
International Journal of Cancer, 2007 AbstracthBVR functions in the cell as a reductase and as a kinase. In the first capacity, it reduces biliverdin, the product of HO activity, to the effective intracellular antioxidant, bilirubin; as a dual‐specificity kinase (S/T/Y) it activates the MAPK and IGF/IRK receptor signal transduction pathways. NF‐κB and the MAPK pathway are activated by ROS,
Peter E M Gibbs, Mahin D Maines
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Eggshell Biliverdin as an Antioxidant Maternal Effect [PDF]
BioEssays, 2020 AbstractIn this essay, the hypothesis that biliverdin pigment plays an antioxidant role in the avian eggshell is proposed. Due to its ability to scavenge free radical species and to reduce mutation, biliverdin potentially counteracts the oxidative action of pathogens that penetrate the eggshell and/or protects the shell membrane from oxidation, thus ...
Judith Morales
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Integrated transcriptomic and metabolomic analysis reveals mechanisms of eggshell color variation in Pekin ducks [PDF]
Poultry ScienceGreen-shelled eggs are widely recognized for their high quality, nutritional value, and superior shell strength, making them highly attractive to consumers.
Longxin Wang +5 more
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Direct antioxidant properties of bilirubin andbiliverdin. Is there a role for biliverdin reductase? [PDF]
Frontiers in Pharmacology, 2012 Reactive oxygen species (ROS) and signaling events are involved in the pathogenesis of endothelial dysfunction and represent a major contribution to vascular regulation. Molecular signaling is highly dependent on reactive oxygen species. But depending on
Thomas eJansen, Andreas eDaiber
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Live-cell tracking of biliverdin trafficking reveals metabolic exchange between plastids and peroxisomes [PDF]
Biology OpenMone Shibata +3 more
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EXCLI Journal : Experimental and Clinical Sciences, 2021 Biliverdin reductase, biliverdin and bilirubin are known as important components of cellular signaling pathways that play major roles in cell proliferation and apoptosis, although their physiological relevance is still under evaluation.
Seyedeh Zahra Shahrokhi +2 more
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