Results 41 to 50 of about 23,131 (216)

Interactions between Biliverdin, Oxidative Damage, and Spleen Morphology after Simulated Aggressive Encounters in Veiled Chameleons. [PDF]

open access: yesPLoS ONE, 2015
Stressors frequently increase oxidative damage--unless organisms simultaneously mount effective antioxidant responses. One putative mitigative mechanism is the use of biliverdin, an antioxidant produced in the spleen during erythrocyte degradation.
Michael W Butler, Russell A Ligon
doaj   +1 more source

A new molecular mechanism supports that blue-greenish egg color evolved independently across chicken breeds

open access: yesPoultry Science, 2022
: Chicken blue-greenish coloration (BGC) was known as a classic Mendel trait caused by a retrovirus (EAV-HP) insertion in the SLCO1B3 gene. Lueyang black-boned chicken (LBC) BGC is light and varies continuously, implying that LBC BGC may be controlled by
Qiu Chen, Zhepeng Wang
doaj   +1 more source

Cycling the Wagons for Biliverdin Reductase [PDF]

open access: yesJournal of Biological Chemistry, 2009
This letter was prompted by our reading of the article by Maghzal et al. (1). Bilirubin (BR) is a major physiologic antioxidant cytoprotectant. Tissue levels are only in nanomolar concentrations, because high levels are neurotoxic, yet BR protects against micromolar levels of oxidants because of a cycle wherein biliverdin (BV) generated by BR ...
Thomas W, Sedlak, Solomon H, Snyder
openaire   +2 more sources

Near Infrared Photoswitching by Direct Excitation—A Next Frontier

open access: yesAngewandte Chemie International Edition, EarlyView.
Molecular photoswitches finally enter the spectral realm of near‐infrared for their direct excitation. This minireview summarizes the current state‐of‐the‐art, the design principles for achieving such low‐energy light responsiveness, and the unique applications that are unlocked by it.
Diptiprava Sahoo   +2 more
wiley   +1 more source

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung   +12 more
wiley   +1 more source

Biliverdin reductase-A protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment

open access: yes, 2011
Biliverdin reductase-A is a pleiotropic enzyme involved not only in the reduction of biliverdin-IX-alpha into bilirubin-IX-alpha, but also in the regulation of glucose metabolism and cell growth secondary to its serine/threonine/tyrosine kinase activity.
CENINI G   +22 more
core   +1 more source

Transforming Growth Factor‐β (TGF‐β)–Dependent Iron Homeostasis and Altered TGF‐β Responsiveness in FLVCR1‐Deficient CD4 T Cells

open access: yesBarrier Immunity, EarlyView.
Negative feedback resulting from continuous TGFβRI expression in FLVCR1‐deficient CD4 T cells. Unlike in normal CD4 T cells, TGF‐βRI is not degraded upon activation in FLVCR1‐deficient CD4 T cells. Sustained receptor expression results in increased TGF‐β, leading to dysregulated iron homeostasis, impaired cell proliferation, and enhanced cell death ...
Amber L. Siglin   +3 more
wiley   +1 more source

Identification of biliverdin IXα by mass spectrometry.

open access: yes, 2022
(A) extracted-ion chromatogram (EIC) of organic extract of purified spike protein identifies a prominent peak with an elution time of 9.185 min. (B) MS analysis of the peak in panel a identifies a major ion species with an m/z of 583.2551 consistent to ...
Qiuluan Chen (5492768)   +13 more
core   +1 more source

Biliverdin–copper complex at physiological pH [PDF]

open access: yesDalton Transactions, 2019
In physiological settings, biliverdin and Cu 2+ build a paramagnetic complex with formal structure: radical cation/Cu 1+ or radical anion/Cu 3+ .
Milena S. Dimitrijević   +8 more
openaire   +10 more sources

Proteomic Analysis of ARF1‐ and ARF3‐Proximal Proteins at the Trans‐Golgi Network

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Despite its fundamental importance, the molecular mechanisms of post‐Golgi transport remain incompletely understood. Carrier formation of post‐Golgi transport depends on ARF3 and ARF1, very close paralogs; the former localizes on the trans‐Golgi network (TGN) whereas the latter localizes on TGN and cis‐Golgi.
Taisei Uehara   +3 more
wiley   +1 more source

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