Results 21 to 30 of about 20,102 (177)
Biliverdin regulates NR2E3 and zebrafish retinal photoreceptor development
Scientific Reports, 2022 NR2E3 is an orphan nuclear receptor whose loss-of-function causes abnormal retinal photoreceptor development and degeneration. However, despite that many nuclear receptors are regulated by binding of small molecule ligands, biological small molecule ...
Blaine Connor +5 more
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Enzymological and structural characterization of Arabidopsis thaliana heme oxygenase‐1
FEBS Open Bio, 2022 Arabidopsis thaliana heme oxygenase‐1 (AtHO‐1), a metabolic enzyme in the heme degradation pathway, serves as a prototype for study of the bilin‐related functions in plants.
Jia Wang +6 more
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Molecules, 2023 In this work we review research activities on a few of the most relevant structural aspects of bilirubin (BR) and biliverdin (BV). Special attention is paid to the exocyclic C=C bonds being in mostly Z rather than E configurations, and to the overall ...
Giovanna Longhi +6 more
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Biliverdin Reductase-A Deficiency Brighten and Sensitize Biliverdin-binding Chromoproteins
Cell Structure and Function, 2020 Tissue absorbance, light scattering, and autofluorescence are significantly lower in the near-infrared (NIR) range than in the visible range. Because of these advantages, NIR fluorescent proteins (FPs) are in high demand for in vivo imaging. Nevertheless, application of NIR FPs such as iRFP is still limited due to their dimness in mammalian cells.
Sumiyama, Kenta +5 more
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Biliverdin incorporation into the cyanobacteriochrome SPI1085g3 from Spirulina
Frontiers in Microbiology, 2022 Cyanobacteriochromes (CBCRs) bind linear tetrapyrrole chromophores, mostly phycocyanobilin (PCB), and exhibit considerable spectral diversity with a high potential for biotechnological applications.
Xian-Jun Wu +8 more
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Scalable production of biliverdin IXα by
BMC Biotechnology, 2012 Background Biliverdin IXα is produced when heme undergoes reductive ring cleavage at the α-methene bridge catalyzed by heme oxygenase. It is subsequently reduced by biliverdin reductase to bilirubin IXα which is a potent endogenous antioxidant ...
Chen Dong +4 more
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Poultry Science, 2022 : Eggshell color is the most intuitive external feature that affects consumer acceptance. Different eggshell colors are mainly determined by protoporphyrin IX and biliverdin content. The selection of eggshell color by the human eye with an eggshell color
Lingsen Zeng +4 more
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Cryo-EM structures of mitochondrial ABC transporter ABCB10 in apo and biliverdin-bound form
Nature Communications, 2023 ABCB10, a member of ABC transporter superfamily that locates in the inner membrane of mitochondria, plays crucial roles in hemoglobin synthesis, antioxidative stress and stabilization of the iron transporter mitoferrin-1.
Sheng Cao +7 more
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The Role of Bilirubin and the Other “Yellow Players” in Neurodegenerative Diseases
Antioxidants, 2020 Bilirubin is a yellow endogenous derivate of the heme catabolism. Since the 1980s, it has been recognized as one of the most potent antioxidants in nature, able to counteract 10,000× higher intracellular concentrations of H2O2.
Sri Jayanti +3 more
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Journal of Biological Engineering, 2019 Background Biliverdin, a prospective recyclable antioxidant and one of the most important precursors for optogenetics, has received growing attention. Biliverdin is currently produced by oxidation of bilirubin from mammalian bile using chemicals. However,
Jiho Seok +4 more
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